Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TIFA
  • Mouse genes Tifa
  • Rat genes Tifa
  • Zfish genes tifa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tifa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q12933	Human	PMID:11798190
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:P70196	Human	PMID:15047173
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q6ZNK6	Human	PMID:15047173
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O14641	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q12933	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9BXS5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9H190	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q5TAX3-1	Human	PMID:16643855
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O95379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:P32969	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q8N4T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q99757	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9BXS5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9UBU9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9Y4K3	Human	PMID:26068852
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O00560	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O14641	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9H190	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9Y4K3	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q96QP1	Human	PMID:30111836
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q8N4T4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q6ZNK6	Human	PMID:32101751
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:O60443	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:P32969	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:P57055	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9BXS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIFA	IPI	UniProtKB:Q9UBU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tifa	IPI	UniProtKB:P70196|UniProtKB:Q62406	Mouse	MGI:MGI:3687915|PMID:12566447
Molecular Function	GO:0005515	protein binding	Tifa	IPI	PR:P39429	Mouse	PMID:11798190
Cellular Component	GO:0005737	cytoplasm	TIFA	IDA		Human	PMID:22566686
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	TIFA	IDA		Human	PMID:26068852
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	TIFA	IDA		Human	PMID:28222186
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	TIFA	IDA		Human	PMID:28877472
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	TIFA	IDA		Human	PMID:30111836
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Tifa	IDA		Mouse	PMID:11798190
Biological Process	GO:0045087	innate immune response	TIFA	IDA		Human	PMID:26068852
Biological Process	GO:0045087	innate immune response	TIFA	IDA		Human	PMID:28222186
Biological Process	GO:0045087	innate immune response	TIFA	IDA		Human	PMID:28877472
Biological Process	GO:0045087	innate immune response	TIFA	IDA		Human	PMID:30111836
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TIFA	IDA		Human	PMID:26068852
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TIFA	IDA		Human	PMID:28222186
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TIFA	IDA		Human	PMID:28877472
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TIFA	IDA		Human	PMID:30111836
Biological Process	GO:0051260	protein homooligomerization	TIFA	IDA		Human	PMID:22566686

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern