Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TIMM8A
  • Mouse genes Timm8a1
  • Rat genes Timm8a1
  • Zfish genes timm8a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Timm8a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TIMM8A	IPI	UniProtKB:O60220	Human	PMID:11956200
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q9Y5L4	Human	PMID:11956200
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:O75886	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:O75886	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:O75886	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q969G5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q99856	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q9BXJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:P48643	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q53GS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TIMM8A	IPI	UniProtKB:Q8WUW1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Timm8a1	IPI	RGD:1564499	Rat	PMID:12745081|RGD:724770
Molecular Function	GO:0008270	zinc ion binding	Timm8a1	IDA		Rat	PMID:12745081|RGD:724770
Cellular Component	GO:0005758	mitochondrial intermembrane space	TIMM8A	IDA		Human	PMID:14726512
Cellular Component	GO:0042719	mitochondrial intermembrane space protein transporter complex	TIMM8A	IPI		Human	PMID:11956200
Cellular Component	GO:0005739	mitochondrion	TIMM8A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	TIMM8A	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	Timm8a1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Timm8a1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Timm8a1	IDA		Rat	PMID:12745081|RGD:724770
Biological Process	GO:0006626	protein targeting to mitochondrion	Timm8a1	IDA		Rat	PMID:12745081|RGD:724770

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern