Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TIMP4
  • Mouse genes Timp4
  • Rat genes Timp4
  • Zfish genes timp4.1,timp4.2,timp4.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Timp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	timp4.1	IPI	ZFIN:ZDB-GENE-070817-3	Zfish	PMID:31816958
Molecular Function	GO:0005515	protein binding	timp4.1	IPI	ZFIN:ZDB-GENE-070817-2	Zfish	PMID:31816958
Cellular Component	GO:0005615	extracellular space	Timp4	IDA		Rat	PMID:12707244|RGD:2290461
Cellular Component	GO:0030017	sarcomere	Timp4	IDA		Rat	PMID:12707244|RGD:2290461
Biological Process	GO:0007417	central nervous system development	Timp4	IEP		Rat	PMID:11044612|RGD:2290466
Biological Process	GO:0007219	Notch signaling pathway	Timp4	IDA		Mouse	PMID:23117660
Biological Process	GO:0042698	ovulation cycle	Timp4	IEP		Rat	PMID:12493716|RGD:1302332
Biological Process	GO:0034097	response to cytokine	Timp4	IEP		Rat	PMID:10435007|RGD:2290469
Biological Process	GO:0009725	response to hormone	Timp4	IEP		Rat	PMID:17275272|RGD:2290459
Biological Process	GO:0032496	response to lipopolysaccharide	Timp4	IEP		Rat	PMID:16880766|RGD:2290456
Biological Process	GO:0043434	response to peptide hormone	Timp4	IEP		Rat	PMID:17707437|RGD:2290457
Biological Process	GO:0009410	response to xenobiotic stimulus	Timp4	IEP		Rat	PMID:11851355|RGD:2290464

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern