Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TJP3
  • Mouse genes Tjp3
  • Rat genes Tjp3
  • Zfish genes tjp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tjp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TJP3	IPI	UniProtKB:Q9NPG3	Human	PMID:18823282
Molecular Function	GO:0005515	protein binding	TJP3	IPI	UniProtKB:K9N5R3	Human	PMID:33864728
Molecular Function	GO:0005515	protein binding	Tjp3	IPI	UniProtKB:O35054|UniProtKB:O54942|UniProtKB:O88551|UniProtKB:O88552|UniProtKB:Q9Z0G9|UniProtKB:Q9Z260|UniProtKB:Q9Z261|UniProtKB:Q9Z262	Mouse	MGI:MGI:1350677|PMID:10601346
Molecular Function	GO:0005515	protein binding	Tjp3	IPI	PR:P25322	Mouse	PMID:21411630
Cellular Component	GO:0016324	apical plasma membrane	Tjp3	IDA		Mouse	PMID:14622136
Cellular Component	GO:0005923	bicellular tight junction	TJP3	IDA		Human	PMID:18823282
Cellular Component	GO:0005923	bicellular tight junction	Tjp3	IDA		Mouse	PMID:17000770
Cellular Component	GO:0005923	bicellular tight junction	Tjp3	IDA		Mouse	PMID:14622136
Cellular Component	GO:0005923	bicellular tight junction	tjp3	IDA		Zfish	PMID:18275946
Cellular Component	GO:0030054	cell junction	TJP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005911	cell-cell junction	Tjp3	IDA		Mouse	MGI:MGI:6368095|PMID:25486565
Cellular Component	GO:0005911	cell-cell junction	Tjp3	IDA		Rat	PMID:25486565|RGD:14995318
Cellular Component	GO:0005829	cytosol	Tjp3	IDA		Mouse	MGI:MGI:6368095|PMID:25486565
Cellular Component	GO:0005654	nucleoplasm	TJP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TJP3	IDA		Human	PMID:18823282
Cellular Component	GO:0005634	nucleus	Tjp3	IDA		Mouse	MGI:MGI:6368095|PMID:25486565
Cellular Component	GO:0005886	plasma membrane	TJP3	IDA		Human	GO_REF:0000052
Biological Process	GO:0048871	multicellular organismal-level homeostasis	tjp3	IMP	ZFIN:ZDB-MRPHLNO-080623-2	Zfish	PMID:18275946
Biological Process	GO:0048871	multicellular organismal-level homeostasis	tjp3	IMP	ZFIN:ZDB-MRPHLNO-080623-1	Zfish	PMID:18275946
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	tjp3	IMP	ZFIN:ZDB-MRPHLNO-080623-2	Zfish	PMID:18275946
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	tjp3	IMP	ZFIN:ZDB-MRPHLNO-080623-1	Zfish	PMID:18275946
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	Tjp3	IGI	MGI:MGI:88313	Mouse	PMID:21411630

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern