Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TKFC
  • Mouse genes Tkfc
  • Rat genes Tkfc
  • Zfish genes tkfc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tkfc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034012	FAD-AMP lyase (cyclizing) activity	TKFC	IDA		Human	PMID:16289032
Molecular Function	GO:0004371	glycerone kinase activity	TKFC	IDA		Human	PMID:16289032
Molecular Function	GO:0004371	glycerone kinase activity	TKFC	IDA		Human	PMID:32004446
Molecular Function	GO:0004371	glycerone kinase activity	TKFC	IDA		Human	PMID:4688871
Molecular Function	GO:0005515	protein binding	TKFC	IPI	UniProtKB:Q9BYX4	Human	PMID:17600090
Molecular Function	GO:0005515	protein binding	TKFC	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Tkfc	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0050354	triokinase activity	TKFC	IDA		Human	PMID:32004446
Molecular Function	GO:0050354	triokinase activity	TKFC	IDA		Human	PMID:4688871
Molecular Function	GO:0050354	triokinase activity	Tkfc	IDA		Mouse	PMID:18429748
Molecular Function	GO:0050354	triokinase activity	Tkfc	IDA		Mouse	PMID:15652177
Molecular Function	GO:0050354	triokinase activity	Tkfc	IDA		Rat	PMID:8166629|RGD:152025524
Cellular Component	GO:0005829	cytosol	Tkfc	IDA		Rat	PMID:8166629|RGD:152025524
Cellular Component	GO:0070062	extracellular exosome	TKFC	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TKFC	HDA		Human	PMID:23533145
Cellular Component	GO:0005634	nucleus	TKFC	HDA		Human	PMID:21630459
Biological Process	GO:0005975	carbohydrate metabolic process	TKFC	IDA		Human	PMID:16289032
Biological Process	GO:0005975	carbohydrate metabolic process	TKFC	IDA		Human	PMID:4688871
Biological Process	GO:0046835	carbohydrate phosphorylation	TKFC	IDA		Human	PMID:4688871
Biological Process	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	Tkfc	IMP	MGI:MGI:6471029	Mouse	PMID:32818435
Biological Process	GO:0039534	negative regulation of MDA-5 signaling pathway	TKFC	IDA		Human	PMID:17600090
Biological Process	GO:0045088	regulation of innate immune response	TKFC	IDA		Human	PMID:16289032

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern