Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tlr2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TLR2
- Mouse genes Tlr2
- Rat genes Tlr2
- Zfish genes tlr2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tlr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	TLR2	IDA		Human	PMID:22198949
Molecular Function	GO:0001540	amyloid-beta binding	Tlr2	IDA		Mouse	MGI:MGI:5307186\|PMID:22198949
Molecular Function	GO:0042498	diacyl lipopeptide binding	Tlr2	IDA		Mouse	PMID:17889651
Molecular Function	GO:0042498	diacyl lipopeptide binding	Tlr2	IDA		Mouse	PMID:19931471
Molecular Function	GO:0042802	identical protein binding	TLR2	IPI	UniProtKB:O60603	Human	PMID:23155421
Molecular Function	GO:0071723	lipopeptide binding	Tlr2	IMP		Rat	PMID:18353287\|RGD:5684896
Molecular Function	GO:0001530	lipopolysaccharide binding	TLR2	IDA		Human	PMID:11274165
Molecular Function	GO:0070891	lipoteichoic acid binding	Tlr2	IDA		Mouse	PMID:19931471
Molecular Function	GO:0038187	pattern recognition receptor activity	TLR2	IDA		Human	PMID:10384090
Molecular Function	GO:0042834	peptidoglycan binding	TLR2	IDA		Human	PMID:11986301
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q9H0E2	Human	PMID:11441107
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P9WK61	Human	PMID:12594264
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q15654	Human	PMID:15657077
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q9BXR5	Human	PMID:15728506
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q99836	Human	PMID:16293622
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P9WGU1	Human	PMID:16622205
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P08571,UniProtKB:P16671,UniProtKB:Q9Y2C9	Human	PMID:16880211
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P08571,UniProtKB:Q15399	Human	PMID:16880211
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P9WIF5	Human	PMID:17095513
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P00533	Human	PMID:17126326
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q99836	Human	PMID:17126326
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P61073	Human	PMID:18765807
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P58753	Human	PMID:19509286
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q7D8M9	Human	PMID:19880448
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q9Y2C9	Human	PMID:20067962
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:C3PTT6	Human	PMID:20802527
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P61073	Human	PMID:20802527
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q15399	Human	PMID:23155421
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q9BXR5	Human	PMID:23155421
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q9Y2C9	Human	PMID:23155421
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q676U5	Human	PMID:23376921
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:Q99836	Human	PMID:29990310
Molecular Function	GO:0005515	protein binding	TLR2	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Tlr2	IPI	UniProtKB:Q99JY1	Mouse	MGI:MGI:4943396\|PMID:17322885
Molecular Function	GO:0005515	protein binding	Tlr2	IPI	UniProtKB:P22366	Mouse	MGI:MGI:3639312\|PMID:16832055
Molecular Function	GO:0005515	protein binding	Tlr2	IPI	UniProtKB:P22366	Mouse	MGI:MGI:6202827\|PMID:29990310
Molecular Function	GO:0005515	protein binding	Tlr2	IPI	UniProtKB:Q8K1L5	Mouse	MGI:MGI:6094454\|PMID:27805901
Molecular Function	GO:0005515	protein binding	Tlr2	IPI	PR:Q9EPW9	Mouse	PMID:19931471
Molecular Function	GO:0005515	protein binding	Tlr2	IPI	RGD:735043	Rat	PMID:19144836\|RGD:2312510
Molecular Function	GO:0044877	protein-containing complex binding	TLR2	IPI	ComplexPortal:CPX-1134	Human	PMID:22198949
Molecular Function	GO:0044877	protein-containing complex binding	Tlr2	IPI	ComplexPortal:CPX-1134	Mouse	MGI:MGI:5307186\|PMID:22198949
Molecular Function	GO:0035325	Toll-like receptor binding	TLR2	IPI	UniProtKB:Q15399\|UniProtKB:Q9Y2C9	Human	PMID:16880211
Molecular Function	GO:0042497	triacyl lipopeptide binding	TLR2	IDA		Human	PMID:17889651
Molecular Function	GO:0042497	triacyl lipopeptide binding	Tlr2	IDA		Mouse	PMID:17889651
Cellular Component	GO:0044297	cell body	Tlr2	IDA		Rat	PMID:21971760\|RGD:7241097
Cellular Component	GO:0042995	cell projection	Tlr2	IDA		Rat	PMID:21971760\|RGD:7241097
Cellular Component	GO:0009986	cell surface	TLR2	IDA		Human	PMID:12443841
Cellular Component	GO:0009986	cell surface	Tlr2	IDA		Rat	PMID:21765618\|RGD:7241098
Cellular Component	GO:0005737	cytoplasm	TLR2	IDA		Human	PMID:19740627
Cellular Component	GO:0009897	external side of plasma membrane	Tlr2	IDA		Mouse	PMID:15220916
Cellular Component	GO:0005794	Golgi apparatus	TLR2	IDA		Human	PMID:16880211
Cellular Component	GO:0045121	membrane raft	TLR2	IDA		Human	PMID:16880211
Cellular Component	GO:0005886	plasma membrane	TLR2	IDA		Human	PMID:11274165
Cellular Component	GO:0005886	plasma membrane	TLR2	IDA		Human	PMID:19740627
Cellular Component	GO:0005886	plasma membrane	TLR2	IDA		Human	PMID:19509287
Cellular Component	GO:0005886	plasma membrane	Tlr2	IDA		Mouse	PMID:12719478
Cellular Component	GO:0043235	receptor complex	TLR2	IPI		Human	PMID:23155421
Cellular Component	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex	TLR2	IPI		Human	PMID:17889651
Cellular Component	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex	TLR2	IDA		Human	PMID:17889651
Cellular Component	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex	TLR2	IPI		Human	PMID:23155421
Cellular Component	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex	Tlr2	IPI	PR:Q9EPW9	Mouse	PMID:19931471
Biological Process	GO:0002253	activation of immune response	tlr2	IMP	ZFIN:ZDB-MRPHLNO-151201-1	Zfish	PMID:26208853
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:12719478
Biological Process	GO:0071221	cellular response to bacterial lipopeptide	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0071726	cellular response to diacyl bacterial lipopeptide	TLR2	IDA		Human	PMID:19931471
Biological Process	GO:0071726	cellular response to diacyl bacterial lipopeptide	TLR2	IDA		Human	PMID:16880211
Biological Process	GO:0071223	cellular response to lipoteichoic acid	TLR2	IDA		Human	PMID:12594207
Biological Process	GO:0071223	cellular response to lipoteichoic acid	TLR2	IMP		Human	PMID:26649771
Biological Process	GO:0071223	cellular response to lipoteichoic acid	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0071224	cellular response to peptidoglycan	Tlr2	IMP		Mouse	PMID:16949315
Biological Process	GO:0071727	cellular response to triacyl bacterial lipopeptide	TLR2	IDA		Human	PMID:19931471
Biological Process	GO:0071727	cellular response to triacyl bacterial lipopeptide	TLR2	IDA		Human	PMID:16880211
Biological Process	GO:0071346	cellular response to type II interferon	TLR2	IDA		Human	PMID:11672593
Biological Process	GO:0032289	central nervous system myelin formation	Tlr2	IDA		Rat	PMID:21971760\|RGD:7241097
Biological Process	GO:0032602	chemokine production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0006952	defense response	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:12091878
Biological Process	GO:0050830	defense response to Gram-positive bacterium	TLR2	IDA		Human	PMID:11521063
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:19139201
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0051607	defense response to virus	TLR2	IEP		Human	PMID:32634389
Biological Process	GO:0042496	detection of diacyl bacterial lipopeptide	TLR2	IDA		Human	PMID:19931471
Biological Process	GO:0042495	detection of triacyl bacterial lipopeptide	TLR2	IDA		Human	PMID:19931471
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:22033934
Biological Process	GO:0007252	I-kappaB phosphorylation	TLR2	IDA		Human	PMID:19740627
Biological Process	GO:0006955	immune response	tlr2	IMP	ZFIN:ZDB-GENO-201105-12	Zfish	PMID:31747871
Biological Process	GO:0006955	immune response	tlr2	IMP	ZFIN:ZDB-GENO-201104-1	Zfish	PMID:31747871
Biological Process	GO:0006954	inflammatory response	Tlr2	IDA		Rat	PMID:16154916\|RGD:4889539
Biological Process	GO:0032620	interleukin-17 production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0032635	interleukin-6 production	Tlr2	IDA		Mouse	PMID:18261938
Biological Process	GO:0032635	interleukin-6 production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0032635	interleukin-6 production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0007612	learning	Tlr2	IGI	UniProtKB:P05067,UniProtKB:P49768	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0050900	leukocyte migration	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:17114491
Biological Process	GO:0006691	leukotriene metabolic process	Tlr2	IDA		Rat	PMID:21765618\|RGD:7241098
Biological Process	GO:0010934	macrophage cytokine production	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0010934	macrophage cytokine production	Tlr2	IDA		Mouse	PMID:18261938
Biological Process	GO:0010934	macrophage cytokine production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0010934	macrophage cytokine production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0014005	microglia development	Tlr2	IGI	UniProtKB:P05067,UniProtKB:P49768	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0001774	microglial cell activation	Tlr2	IDA		Rat	PMID:16973131\|RGD:1643119
Biological Process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	Tlr2	IGI	MGI:MGI:108005	Mouse	PMID:12719478
Biological Process	GO:0030837	negative regulation of actin filament polymerization	Tlr2	IGI	ComplexPortal:CPX-1134	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0008285	negative regulation of cell population proliferation	Tlr2	IDA		Rat	PMID:21971760\|RGD:7241097
Biological Process	GO:0032695	negative regulation of interleukin-12 production	Tlr2	IMP		Mouse	PMID:16949315
Biological Process	GO:0032700	negative regulation of interleukin-17 production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0050765	negative regulation of phagocytosis	Tlr2	IMP		Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0050765	negative regulation of phagocytosis	Tlr2	IGI	UniProtKB:P05067,UniProtKB:P49768	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0051964	negative regulation of synapse assembly	Tlr2	IGI	UniProtKB:P05067,UniProtKB:P49768	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:1990266	neutrophil migration	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:17114491
Biological Process	GO:0038061	NIK/NF-kappaB signaling	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:22033934
Biological Process	GO:0006809	nitric oxide biosynthetic process	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0006809	nitric oxide biosynthetic process	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0046209	nitric oxide metabolic process	Tlr2	IDA		Rat	PMID:16973131\|RGD:1643119
Biological Process	GO:1903974	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	TLR2	IDA		Human	PMID:11672593
Biological Process	GO:0032722	positive regulation of chemokine production	TLR2	IDA		Human	PMID:19740627
Biological Process	GO:0032722	positive regulation of chemokine production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0001819	positive regulation of cytokine production	Tlr2	IGI	MGI:MGI:2157947	Mouse	PMID:19770268
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:22033934
Biological Process	GO:0010628	positive regulation of gene expression	TLR2	IMP		Human	PMID:23817958
Biological Process	GO:0010628	positive regulation of gene expression	TLR2	IMP		Human	PMID:26649771
Biological Process	GO:0050729	positive regulation of inflammatory response	TLR2	IGI	RNAcentral:URS000006FDD4_9606	Human	PMID:28078022
Biological Process	GO:0050729	positive regulation of inflammatory response	Tlr2	IGI	ComplexPortal:CPX-1134	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0032728	positive regulation of interferon-beta production	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Tlr2	IGI	ComplexPortal:CPX-1134	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0032733	positive regulation of interleukin-10 production	Tlr2	IDA		Rat	PMID:22653369\|RGD:7241093
Biological Process	GO:0032735	positive regulation of interleukin-12 production	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0032741	positive regulation of interleukin-18 production	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0032755	positive regulation of interleukin-6 production	TLR2	IDA		Human	PMID:19740627
Biological Process	GO:0032755	positive regulation of interleukin-6 production	TLR2	IGI	RNAcentral:URS000006FDD4_9606	Human	PMID:28078022
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tlr2	IDA		Mouse	PMID:18261938
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TLR2	IDA		Human	PMID:17128265
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TLR2	IDA		Human	PMID:19740627
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TLR2	IGI	ComplexPortal:CPX-1134	Human	PMID:22198949
Biological Process	GO:0002687	positive regulation of leukocyte migration	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:17114491
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Tlr2	IDA		Mouse	PMID:18261938
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:1904466	positive regulation of matrix metallopeptidase secretion	TLR2	IGI	RNAcentral:URS000006FDD4_9606	Human	PMID:28078022
Biological Process	GO:1902624	positive regulation of neutrophil migration	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:17114491
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TLR2	IDA		Human	PMID:12594207
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TLR2	IDA		Human	PMID:21618349
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TLR2	IDA		Human	PMID:19740627
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:22033934
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	Tlr2	IDA		Rat	PMID:21971760\|RGD:7241097
Biological Process	GO:0034123	positive regulation of toll-like receptor signaling pathway	TLR2	IDA		Human	PMID:17128265
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IGI	ComplexPortal:CPX-1134	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IGI	UniProtKB:P05067,UniProtKB:P49768	Mouse	MGI:MGI:5307186\|PMID:22198949
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IDA		Mouse	MGI:MGI:4456948\|PMID:15356140
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:12719478
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	TLR2	IMP		Human	PMID:16601243
Biological Process	GO:1904417	positive regulation of xenophagy	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:22033934
Biological Process	GO:0002730	regulation of dendritic cell cytokine production	Tlr2	IDA		Mouse	PMID:19047410
Biological Process	GO:0032493	response to bacterial lipoprotein	Tlr2	IDA		Rat	PMID:16973131\|RGD:1643119
Biological Process	GO:0009617	response to bacterium	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:17114491
Biological Process	GO:0070542	response to fatty acid	Tlr2	IDA		Rat	PMID:19144836\|RGD:2312510
Biological Process	GO:0001666	response to hypoxia	Tlr2	IEP		Rat	PMID:15535030\|RGD:2312731
Biological Process	GO:0032868	response to insulin	Tlr2	IEP		Rat	PMID:16740310\|RGD:2312491
Biological Process	GO:0032496	response to lipopolysaccharide	Tlr2	IEP		Rat	PMID:11028557\|RGD:2312734
Biological Process	GO:0002238	response to molecule of fungal origin	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:12719478
Biological Process	GO:0032494	response to peptidoglycan	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:17114491
Biological Process	GO:0032494	response to peptidoglycan	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0032570	response to progesterone	Tlr2	IEP		Rat	PMID:18316784\|RGD:2312713
Biological Process	GO:0009636	response to toxic substance	Tlr2	IEP		Rat	PMID:15535030\|RGD:2312731
Biological Process	GO:0002224	toll-like receptor signaling pathway	TLR2	IDA		Human	PMID:16893894
Biological Process	GO:0002224	toll-like receptor signaling pathway	Tlr2	IDA		Rat	PMID:16973131\|RGD:1643119
Biological Process	GO:0002224	toll-like receptor signaling pathway	Tlr2	IMP		Rat	PMID:18353287\|RGD:5684896
Biological Process	GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	TLR2	IDA		Human	PMID:23626692
Biological Process	GO:0032640	tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:11067888
Biological Process	GO:0032640	tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:16239543
Biological Process	GO:0032640	tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2178675	Mouse	PMID:10549626
Biological Process	GO:0032640	tumor necrosis factor production	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:15690042
Biological Process	GO:0098792	xenophagy	Tlr2	IMP	MGI:MGI:2674036	Mouse	PMID:22033934

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.