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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tlr5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tlr5
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005149interleukin-1 receptor bindingTLR5IPIUniProtKB:Q6IA17HumanPMID:12925853
Molecular FunctionGO:0005515protein bindingTLR5IPIUniProtKB:P05067:PRO_0000000092HumanPMID:30158114
Molecular FunctionGO:0005515protein bindingTLR5IPIUniProtKB:P05067:PRO_0000000093HumanPMID:30158114
Molecular FunctionGO:0005515protein bindingTlr5IPIUniProtKB:A0A0H3NMJ6|UniProtKB:Q56086MouseMGI:MGI:5444760|PMID:23101627
Molecular FunctionGO:0005515protein bindingtlr5bIDAZfishPMID:22344444
Cellular ComponentGO:0016020membraneTlr5IDARatPMID:20856884|RGD:5129496
Biological ProcessGO:0002253activation of immune responsetlr5aIMPZFIN:ZDB-MRPHLNO-100618-2ZfishPMID:26208853
Biological ProcessGO:0002253activation of immune responsetlr5bIMPZFIN:ZDB-MRPHLNO-100618-1ZfishPMID:26208853
Biological ProcessGO:0071222cellular response to lipopolysaccharideTlr5IEPRatPMID:21308757|RGD:5129495
Biological ProcessGO:0071260cellular response to mechanical stimulusTLR5IEPHumanPMID:19593445
Biological ProcessGO:0008584male gonad developmentTlr5IEPRatPMID:19703144|RGD:5129498
Biological ProcessGO:0032757positive regulation of interleukin-8 productionTLR5IDAHumanPMID:17128265
Biological ProcessGO:0045429positive regulation of nitric oxide biosynthetic processTlr5IDARatPMID:16973131|RGD:1643119
Biological ProcessGO:0034123positive regulation of toll-like receptor signaling pathwayTLR5IDAHumanPMID:17128265
Biological ProcessGO:0034146toll-like receptor 5 signaling pathwaytlr5bIDAZfishPMID:22344444
Biological ProcessGO:0002224toll-like receptor signaling pathwaytlr5aIGIZFIN:ZDB-GENE-040219-15ZfishPMID:29555749
Biological ProcessGO:0002224toll-like receptor signaling pathwaytlr5bIGIZFIN:ZDB-GENE-040219-14ZfishPMID:29555749

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory