Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TM6SF1
  • Mouse genes Tm6sf1
  • Rat genes Tm6sf1
  • Zfish genes tm6sf2a,tm6sf2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tm6sf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005765	lysosomal membrane	Tm6sf1	IDA		Mouse	MGI:MGI:5619893|PMID:25422095
Biological Process	GO:0055088	lipid homeostasis	tm6sf2b	IGI	ZFIN:ZDB-MRPHLNO-170719-1,ZFIN:ZDB-MRPHLNO-170719-2	Zfish	PMID:28027591
Biological Process	GO:0055088	lipid homeostasis	tm6sf2b	IMP	ZFIN:ZDB-MRPHLNO-170719-2	Zfish	PMID:28027591
Biological Process	GO:0055088	lipid homeostasis	tm6sf2b	IMP	ZFIN:ZDB-CRISPR-180321-1	Zfish	PMID:28027591
Biological Process	GO:0055088	lipid homeostasis	tm6sf2b	IMP	ZFIN:ZDB-CRISPR-180509-1	Zfish	PMID:28027591
Biological Process	GO:0055088	lipid homeostasis	tm6sf2b	IGI	ZFIN:ZDB-GENO-111222-39	Zfish	PMID:28027591
Biological Process	GO:1905897	regulation of response to endoplasmic reticulum stress	tm6sf2b	IGI	ZFIN:ZDB-MRPHLNO-170719-1,ZFIN:ZDB-MRPHLNO-170719-2	Zfish	PMID:28027591
Biological Process	GO:1905897	regulation of response to endoplasmic reticulum stress	tm6sf2b	IGI	ZFIN:ZDB-GENO-111222-39	Zfish	PMID:28027591
Biological Process	GO:1905897	regulation of response to endoplasmic reticulum stress	tm6sf2b	IMP	ZFIN:ZDB-MRPHLNO-170719-2	Zfish	PMID:28027591

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern