Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TM7SF2
  • Mouse genes Tm7sf2
  • Rat genes Tm7sf2
  • Zfish genes tm7sf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tm7sf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050613	delta14-sterol reductase activity	TM7SF2	IDA		Human	PMID:16784888
Molecular Function	GO:0050613	delta14-sterol reductase activity	Tm7sf2	IMP		Mouse	MGI:MGI:3822946|PMID:18785926
Molecular Function	GO:0050613	delta14-sterol reductase activity	Tm7sf2	IDA		Rat	PMID:16784888|RGD:13825441
Molecular Function	GO:0005515	protein binding	TM7SF2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TM7SF2	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	TM7SF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Tm7sf2	IDA		Rat	PMID:16784888|RGD:13825441
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TM7SF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031090	organelle membrane	Tm7sf2	IDA		Mouse	MGI:MGI:3822946|PMID:18785926
Cellular Component	GO:0031090	organelle membrane	Tm7sf2	IDA		Rat	PMID:16784888|RGD:13825441
Cellular Component	GO:0043235	receptor complex	TM7SF2	IDA		Human	PMID:23382219
Biological Process	GO:0006695	cholesterol biosynthetic process	TM7SF2	IDA		Human	PMID:16784888
Biological Process	GO:0006695	cholesterol biosynthetic process	Tm7sf2	IDA		Mouse	MGI:MGI:3822946|PMID:18785926
Biological Process	GO:0006695	cholesterol biosynthetic process	Tm7sf2	IDA		Rat	PMID:16784888|RGD:13825441

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern