Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMED10
  • Mouse genes Tmed10
  • Rat genes Tmed10
  • Zfish genes tmed10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmed10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q15363	Human	PMID:10359607
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q15363	Human	PMID:12237308
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:P17706-1	Human	PMID:16595549
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:P49768	Human	PMID:16641999
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q15363	Human	PMID:16641999
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q92542	Human	PMID:16641999
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q9NZ42	Human	PMID:16641999
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q15363	Human	PMID:18287528
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q15363	Human	PMID:20427317
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q8XAL7	Human	PMID:23434013
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:P49768	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q9UL25	Human	PMID:31455601
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:P01584	Human	PMID:32272059
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TMED10	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tmed10	IPI	UniProtKB:Q9R064	Rat	PMID:11739402|RGD:2317249
Molecular Function	GO:0008320	protein transmembrane transporter activity	TMED10	IMP		Human	PMID:32272059
Molecular Function	GO:0044877	protein-containing complex binding	Tmed10	IDA		Rat	PMID:10214941|RGD:2317280
Molecular Function	GO:0044877	protein-containing complex binding	Tmed10	IDA		Rat	PMID:11739402|RGD:2317249
Molecular Function	GO:0019905	syntaxin binding	TMED10	IPI	UniProtKB:Q9Z158	Human	PMID:21545355
Cellular Component	GO:0005801	cis-Golgi network	Tmed10	IDA		Rat	PMID:17101722|RGD:2317246
Cellular Component	GO:0030137	COPI-coated vesicle	Tmed10	IDA		Rat	PMID:10214941|RGD:2317280
Cellular Component	GO:0005783	endoplasmic reticulum	TMED10	IDA		Human	PMID:12237308
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	TMED10	IDA		Human	PMID:12237308
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	TMED10	IDA		Human	PMID:32272059
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Tmed10	IDA		Rat	PMID:9914165|RGD:2317252
Cellular Component	GO:0070765	gamma-secretase complex	TMED10	IDA		Human	PMID:16641999
Cellular Component	GO:0070765	gamma-secretase complex	Tmed10	IDA		Mouse	PMID:16641999
Cellular Component	GO:0070765	gamma-secretase complex	Tmed10	IDA		Rat	PMID:19754663|RGD:2317342
Cellular Component	GO:0005794	Golgi apparatus	TMED10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	TMED10	IDA		Human	PMID:12237308
Cellular Component	GO:0000139	Golgi membrane	Tmed10	IDA		Rat	PMID:31455601|RGD:38501078
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Tmed10	IDA		Rat	PMID:8663407|RGD:68840
Cellular Component	GO:0016020	membrane	Tmed10	IDA		Rat	PMID:8663407|RGD:68840
Cellular Component	GO:0005886	plasma membrane	Tmed10	IDA		Rat	PMID:18627576|RGD:8554072
Cellular Component	GO:0030667	secretory granule membrane	Tmed10	IDA		Mouse	MGI:MGI:3710424|PMID:17101722
Cellular Component	GO:0042589	zymogen granule membrane	Tmed10	IDA		Mouse	MGI:MGI:3710424|PMID:17101722
Cellular Component	GO:0042589	zymogen granule membrane	Tmed10	IDA		Rat	PMID:17101722|RGD:2317246
Cellular Component	GO:0042589	zymogen granule membrane	Tmed10	IDA		Rat	PMID:8663407|RGD:68840
Biological Process	GO:0035964	COPI-coated vesicle budding	TMED10	IDA		Human	PMID:10052452
Biological Process	GO:0106273	cytosol to ERGIC protein transport	TMED10	IMP		Human	PMID:32272059
Biological Process	GO:0007030	Golgi organization	Tmed10	IDA		Mouse	MGI:MGI:3526746|PMID:10660306
Biological Process	GO:0007030	Golgi organization	Tmed10	IMP		Rat	PMID:9914165|RGD:2317252
Biological Process	GO:0006886	intracellular protein transport	TMED10	IDA		Human	PMID:20427317
Biological Process	GO:0001822	kidney development	Tmed10	IEP		Rat	PMID:10893644|RGD:2317251
Biological Process	GO:1902960	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Tmed10	IMP		Mouse	PMID:16641999
Biological Process	GO:0032732	positive regulation of interleukin-1 production	TMED10	IMP		Human	PMID:32272059
Biological Process	GO:0032732	positive regulation of interleukin-1 production	Tmed10	IMP		Mouse	MGI:MGI:6442278|PMID:32272059
Biological Process	GO:0050714	positive regulation of protein secretion	TMED10	IMP		Human	PMID:32272059
Biological Process	GO:0050714	positive regulation of protein secretion	Tmed10	IMP		Mouse	MGI:MGI:6442278|PMID:32272059
Biological Process	GO:0106272	protein localization to ERGIC	TMED10	IMP		Human	PMID:32272059
Biological Process	GO:0045055	regulated exocytosis	Tmed10	IEP		Mouse	MGI:MGI:3710424|PMID:17101722
Biological Process	GO:0045055	regulated exocytosis	Tmed10	IEP		Rat	PMID:17101722|RGD:2317246
Biological Process	GO:1902003	regulation of amyloid-beta formation	TMED10	IMP		Human	PMID:16641999
Biological Process	GO:0043279	response to alkaloid	Tmed10	IEP		Rat	PMID:9288726|RGD:2317254
Biological Process	GO:0048199	vesicle targeting, to, from or within Golgi	Tmed10	IEP		Mouse	MGI:MGI:3710424|PMID:17101722
Biological Process	GO:0048199	vesicle targeting, to, from or within Golgi	Tmed10	IEP		Rat	PMID:17101722|RGD:2317246

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern