Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM100
  • Mouse genes Tmem100
  • Rat genes Tmem100
  • Zfish genes tmem100a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem100

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q2TAC2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9BSE2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:O14863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:P15260	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:P20138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q4KMG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q6ZMZ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q86WV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q8N1F7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q8N3G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q96TC7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9BS91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9H7M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9H902	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9NRX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMEM100	IPI	UniProtKB:Q9Y624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tmem100	IPI	UniProtKB:Q704Y3|UniProtKB:Q8BLA8	Mouse	MGI:MGI:5621199|PMID:25640077
Molecular Function	GO:0005515	protein binding	Tmem100	IPI	UniProtKB:Q69ZR9	Mouse	PMID:31112734
Cellular Component	GO:0005783	endoplasmic reticulum	TMEM100	IDA		Human	PMID:22783020
Cellular Component	GO:0043204	perikaryon	TMEM100	IDA		Human	PMID:23485812
Cellular Component	GO:0043204	perikaryon	Tmem100	IDA		Mouse	MGI:MGI:5513063|PMID:23485812
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TMEM100	IDA		Human	PMID:22783020
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Tmem100	IDA		Mouse	PMID:22783020
Cellular Component	GO:0005886	plasma membrane	TMEM100	IDA		Human	PMID:23485812
Cellular Component	GO:0005886	plasma membrane	Tmem100	IDA		Mouse	MGI:MGI:5513063|PMID:23485812
Cellular Component	GO:0005886	plasma membrane	Tmem100	IDA		Mouse	MGI:MGI:5621199|PMID:25640077
Biological Process	GO:0001525	angiogenesis	Tmem100	IMP	MGI:MGI:5432905	Mouse	PMID:22783020
Biological Process	GO:0001525	angiogenesis	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:22783020
Biological Process	GO:0060842	arterial endothelial cell differentiation	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:22783020
Biological Process	GO:0060842	arterial endothelial cell differentiation	Tmem100	IMP	MGI:MGI:5432905	Mouse	PMID:22783020
Biological Process	GO:0030509	BMP signaling pathway	TMEM100	IDA		Human	PMID:22783020
Biological Process	GO:0071773	cellular response to BMP stimulus	TMEM100	IDA		Human	PMID:22783020
Biological Process	GO:0003197	endocardial cushion development	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:25318679
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:25318679
Biological Process	GO:0001701	in utero embryonic development	Tmem100	IMP	MGI:MGI:5432905	Mouse	PMID:22783020
Biological Process	GO:0001701	in utero embryonic development	Tmem100	IMP	MGI:MGI:4881485	Mouse	PMID:20848592
Biological Process	GO:0001701	in utero embryonic development	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:22783020
Biological Process	GO:0007219	Notch signaling pathway	Tmem100	IMP	MGI:MGI:5432905	Mouse	PMID:22783020
Biological Process	GO:0007219	Notch signaling pathway	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:22783020
Biological Process	GO:0045603	positive regulation of endothelial cell differentiation	Tmem100	IMP		Mouse	MGI:MGI:5432418|PMID:22783020
Biological Process	GO:2001214	positive regulation of vasculogenesis	Tmem100	IMP		Mouse	MGI:MGI:5432418|PMID:22783020
Biological Process	GO:0043491	protein kinase B signaling	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:22783020
Biological Process	GO:0043491	protein kinase B signaling	Tmem100	IMP	MGI:MGI:5432905	Mouse	PMID:22783020
Biological Process	GO:0050848	regulation of calcium-mediated signaling	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:25318679
Biological Process	GO:0051930	regulation of sensory perception of pain	Tmem100	IMP		Mouse	MGI:MGI:5621199|PMID:25640077
Biological Process	GO:0001570	vasculogenesis	Tmem100	IMP	MGI:MGI:5432905	Mouse	PMID:22783020
Biological Process	GO:0001570	vasculogenesis	Tmem100	IMP	MGI:MGI:5432904	Mouse	PMID:22783020

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern