Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM119
  • Mouse genes Tmem119
  • Rat genes Tmem119
  • Zfish genes tmem119a,tmem119b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem119

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Tmem119	IPI	PR:Q08775	Mouse	PMID:21239498
Molecular Function	GO:0005515	protein binding	Tmem119	IPI	PR:P70340	Mouse	PMID:21239498
Molecular Function	GO:0005515	protein binding	Tmem119	IPI	PR:P97454	Mouse	PMID:21239498
Cellular Component	GO:0005783	endoplasmic reticulum	Tmem119	IDA		Mouse	PMID:21239498
Cellular Component	GO:0005886	plasma membrane	TMEM119	IDA		Human	PMID:20025746
Cellular Component	GO:0005886	plasma membrane	Tmem119	IDA		Mouse	MGI:MGI:4418582|PMID:20025746
Biological Process	GO:0001958	endochondral ossification	Tmem119	IMP		Mouse	MGI:MGI:5543589|PMID:22416756
Biological Process	GO:0045779	negative regulation of bone resorption	Tmem119	IMP		Mouse	MGI:MGI:5543589|PMID:22416756
Biological Process	GO:0010832	negative regulation of myotube differentiation	Tmem119	IDA		Mouse	MGI:MGI:6294241|PMID:22579779
Biological Process	GO:0001649	osteoblast differentiation	Tmem119	IMP		Mouse	PMID:21239498
Biological Process	GO:0001649	osteoblast differentiation	Tmem119	IDA		Mouse	PMID:21239498
Biological Process	GO:1903012	positive regulation of bone development	Tmem119	IMP		Mouse	MGI:MGI:5700277|PMID:26207632
Biological Process	GO:0030501	positive regulation of bone mineralization	TMEM119	IDA		Human	PMID:20025746
Biological Process	GO:0030501	positive regulation of bone mineralization	Tmem119	IMP		Mouse	MGI:MGI:4418582|PMID:20025746
Biological Process	GO:0030501	positive regulation of bone mineralization	Tmem119	IMP		Mouse	MGI:MGI:5700277|PMID:26207632
Biological Process	GO:0010628	positive regulation of gene expression	Tmem119	IMP		Mouse	MGI:MGI:5543589|PMID:22416756
Biological Process	GO:0010628	positive regulation of gene expression	Tmem119	IDA		Mouse	MGI:MGI:6294241|PMID:22579779
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	TMEM119	IDA		Human	PMID:20025746
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Tmem119	IMP		Mouse	MGI:MGI:5543589|PMID:22416756
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Tmem119	IMP		Mouse	MGI:MGI:4418582|PMID:20025746
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Tmem119	IDA		Mouse	MGI:MGI:6294241|PMID:22579779
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	TMEM119	IDA		Human	PMID:20025746
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	Tmem119	IDA		Mouse	MGI:MGI:4418582|PMID:20025746
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Tmem119	IDA		Mouse	MGI:MGI:6294241|PMID:22579779
Biological Process	GO:0048515	spermatid differentiation	Tmem119	IMP		Mouse	MGI:MGI:5700277|PMID:26207632
Biological Process	GO:0007283	spermatogenesis	Tmem119	IMP		Mouse	MGI:MGI:5700277|PMID:26207632

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern