Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM127
  • Mouse genes Tmem127
  • Rat genes RGD1565472,Tmem127
  • Zfish genes tmem127
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem127

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031267	small GTPase binding	TMEM127	IDA		Human	PMID:24334765
Cellular Component	GO:0005737	cytoplasm	TMEM127	IDA		Human	PMID:20154675
Cellular Component	GO:0005769	early endosome	TMEM127	IDA		Human	PMID:24334765
Cellular Component	GO:0005886	plasma membrane	TMEM127	IDA		Human	PMID:20154675
Biological Process	GO:0007032	endosome organization	Tmem127	IMP	MGI:MGI:5581337	Mouse	PMID:24334765
Biological Process	GO:0008285	negative regulation of cell population proliferation	TMEM127	IMP		Human	PMID:20154675
Biological Process	GO:0032007	negative regulation of TOR signaling	TMEM127	IMP		Human	PMID:20154675
Biological Process	GO:0032006	regulation of TOR signaling	Tmem127	IMP	MGI:MGI:5581337	Mouse	PMID:24334765

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern