Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM216
  • Mouse genes Tmem216
  • Rat genes Tmem216
  • Zfish genes tmem216
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem216

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TMEM216	IPI	UniProtKB:Q6UX40	Human	PMID:26595381
Cellular Component	GO:0035869	ciliary transition zone	Tmem216	IMP		Mouse	MGI:MGI:5288576|PMID:21725307
Cellular Component	GO:0005929	cilium	TMEM216	IDA		Human	PMID:22282472
Cellular Component	GO:0036038	MKS complex	Tmem216	IDA		Mouse	MGI:MGI:5288576|PMID:21725307
Biological Process	GO:0060271	cilium assembly	TMEM216	IMP		Human	PMID:22282472
Biological Process	GO:0060271	cilium assembly	Tmem216	IMP		Mouse	MGI:MGI:5288576|PMID:21725307
Biological Process	GO:0060271	cilium assembly	tmem216	IMP		Zfish	PMID:22282472|ZFIN:ZDB-PUB-200522-20
Biological Process	GO:0060027	convergent extension involved in gastrulation	tmem216	IGI	ZFIN:ZDB-MRPHLNO-120111-8,ZFIN:ZDB-MRPHLNO-120111-9	Zfish	PMID:22152675

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern