Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMEM259
  • Mouse genes Tmem259
  • Rat genes Tmem259
  • Zfish genes tmem259
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmem259

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Tmem259	IPI	UniProtKB:Q8BFZ9	Mouse	MGI:MGI:5648655|PMID:25977983
Cellular Component	GO:0005783	endoplasmic reticulum	Tmem259	IDA		Mouse	MGI:MGI:5648655|PMID:25977983
Biological Process	GO:1901215	negative regulation of neuron death	Tmem259	IMP		Mouse	MGI:MGI:5648655|PMID:25977983
Biological Process	GO:1904294	positive regulation of ERAD pathway	Tmem259	IDA		Mouse	MGI:MGI:5648655|PMID:25977983
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Tmem259	IMP		Mouse	MGI:MGI:5648655|PMID:25977983

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern