Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMF1
  • Mouse genes Tmf1
  • Rat genes Tmf1
  • Zfish genes tmf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050681	nuclear androgen receptor binding	TMF1	IPI	UniProtKB:P10275	Human	PMID:10428808
Molecular Function	GO:0030374	nuclear receptor coactivator activity	TMF1	IDA		Human	PMID:10428808
Molecular Function	GO:0005515	protein binding	TMF1	IPI	UniProtKB:P04150	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	TMF1	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tmf1	IPI	UniProtKB:Q80ZI1	Mouse	MGI:MGI:5488886|PMID:16792503
Cellular Component	GO:0005783	endoplasmic reticulum	Tmf1	IDA		Mouse	PMID:23000399
Cellular Component	GO:0005794	Golgi apparatus	TMF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	Tmf1	IDA		Mouse	PMID:20691678
Cellular Component	GO:0005794	Golgi apparatus	Tmf1	IDA		Mouse	PMID:23000399
Biological Process	GO:0001675	acrosome assembly	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:20691678
Biological Process	GO:0001675	acrosome assembly	Tmf1	IMP	MGI:MGI:4867389	Mouse	PMID:20691678
Biological Process	GO:0030521	androgen receptor signaling pathway	TMF1	IDA		Human	PMID:10428808
Biological Process	GO:0006915	apoptotic process	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0071407	cellular response to organic cyclic compound	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:22531781
Biological Process	GO:0042742	defense response to bacterium	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:22553199
Biological Process	GO:1904019	epithelial cell apoptotic process	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0030317	flagellated sperm motility	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:20691678
Biological Process	GO:0030317	flagellated sperm motility	Tmf1	IMP	MGI:MGI:4867389	Mouse	PMID:20691678
Biological Process	GO:0033327	Leydig cell differentiation	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0032275	luteinizing hormone secretion	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0008584	male gonad development	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0008584	male gonad development	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:20691678
Biological Process	GO:0008584	male gonad development	Tmf1	IMP	MGI:MGI:4867389	Mouse	PMID:20691678
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0010629	negative regulation of gene expression	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:22553199
Biological Process	GO:0001819	positive regulation of cytokine production	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:22553199
Biological Process	GO:2000845	positive regulation of testosterone secretion	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TMF1	IDA		Human	PMID:10428808
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	Tmf1	IDA		Mouse	MGI:MGI:5488886|PMID:16792503
Biological Process	GO:0007286	spermatid development	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:23000399
Biological Process	GO:0007286	spermatid development	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:20691678
Biological Process	GO:0007286	spermatid development	Tmf1	IMP	MGI:MGI:4867389	Mouse	PMID:20691678
Biological Process	GO:0007289	spermatid nucleus differentiation	Tmf1	IMP	MGI:MGI:4867389	Mouse	PMID:20691678
Biological Process	GO:0007289	spermatid nucleus differentiation	Tmf1	IMP	MGI:MGI:4867392	Mouse	PMID:20691678

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern