Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TMSB4X,TMSB4Y
  • Mouse genes Tmsb4x
  • Rat genes LOC120095326
  • Zfish genes tmsb4x
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tmsb4x

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003785	actin monomer binding	TMSB4X	IDA		Human	PMID:1447300
Molecular Function	GO:0003785	actin monomer binding	TMSB4X	IDA		Human	PMID:1999398
Molecular Function	GO:0019899	enzyme binding	TMSB4X	IPI	UniProtKB:P06576	Human	PMID:21106936
Molecular Function	GO:0019899	enzyme binding	TMSB4X	IPI	UniProtKB:P25705	Human	PMID:21106936
Molecular Function	GO:0005515	protein binding	TMSB4Y	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:P40692	Human	PMID:17967441
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:P40692	Human	PMID:20706999
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:Q8IUC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:Q8TAS1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:Q9ULX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:Q9Y2V7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TMSB4X	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tmsb4x	IPI	UniProtKB:Q8WWQ8	Mouse	MGI:MGI:5512835|PMID:18519035
Molecular Function	GO:0005515	protein binding	Tmsb4x	IPI	PR:O55222	Mouse	PMID:15565145
Molecular Function	GO:0005515	protein binding	Tmsb4x	IPI	PR:Q99JW4	Mouse	PMID:15565145
Molecular Function	GO:0003723	RNA binding	TMSB4X	HDA		Human	PMID:22658674
Cellular Component	GO:0005737	cytoplasm	TMSB4X	IDA		Human	PMID:21343177
Cellular Component	GO:0005829	cytosol	TMSB4X	IDA		Human	PMID:1447300
Cellular Component	GO:0005829	cytosol	Tmsb4x	IDA		Mouse	PMID:15565145
Cellular Component	GO:0005576	extracellular region	TMSB4X	HDA		Human	PMID:27068509
Cellular Component	GO:0005634	nucleus	TMSB4X	IDA		Human	PMID:21343177
Cellular Component	GO:0005634	nucleus	Tmsb4x	IDA		Mouse	PMID:15565145
Biological Process	GO:0036302	atrioventricular canal development	tmsb4x	IMP	ZFIN:ZDB-MRPHLNO-140620-8	Zfish	PMID:24732964
Biological Process	GO:0003181	atrioventricular valve morphogenesis	tmsb4x	IMP	ZFIN:ZDB-MRPHLNO-140620-8	Zfish	PMID:24732964
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	TMSB4X	IMP		Human	PMID:21343177
Biological Process	GO:0001947	heart looping	tmsb4x	IMP	ZFIN:ZDB-MRPHLNO-140620-8	Zfish	PMID:24732964
Biological Process	GO:0032717	negative regulation of interleukin-8 production	TMSB4X	IDA		Human	PMID:21343177
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	TMSB4X	IMP		Human	PMID:21343177
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	TMSB4X	IMP		Human	PMID:21343177
Biological Process	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	TMSB4X	IDA		Human	PMID:21343177
Biological Process	GO:2001171	positive regulation of ATP biosynthetic process	TMSB4X	IDA		Human	PMID:21106936
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	TMSB4X	IDA		Human	PMID:21106936
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	TMSB4X	IGI	UniProtKB:P00747:PRO_0000028057	Human	PMID:21106936
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	TMSB4X	IGI	UniProtKB:P06576	Human	PMID:21106936
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	TMSB4X	IGI	UniProtKB:P25705	Human	PMID:21106936
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	TMSB4X	IDA		Human	PMID:21106936
Biological Process	GO:1905273	positive regulation of proton-transporting ATP synthase activity, rotational mechanism	TMSB4X	IDA		Human	PMID:21106936
Biological Process	GO:0048793	pronephros development	tmsb4x	IMP	ZFIN:ZDB-GENO-220922-1	Zfish	PMID:32750455
Biological Process	GO:0030334	regulation of cell migration	Tmsb4x	IDA		Mouse	PMID:15565145
Biological Process	GO:0050727	regulation of inflammatory response	TMSB4X	IMP		Human	PMID:21343177
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	TMSB4X	IGI	UniProtKB:Q04206	Human	PMID:21343177
Biological Process	GO:0042989	sequestering of actin monomers	TMSB4X	IDA		Human	PMID:1447300
Biological Process	GO:0042989	sequestering of actin monomers	TMSB4X	IDA		Human	PMID:1999398
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	TMSB4X	IMP		Human	PMID:21343177

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern