Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNC
  • Mouse genes Tnc
  • Rat genes Tnc
  • Zfish genes tnca,tncb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNC	IPI	UniProtKB:P20908	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	TNC	IPI	UniProtKB:O00206	Human	PMID:29150600
Molecular Function	GO:0045545	syndecan binding	TNC	IDA		Human	PMID:8769660
Cellular Component	GO:0005604	basement membrane	Tnc	IDA		Mouse	PMID:7687262
Cellular Component	GO:0005604	basement membrane	Tnc	IDA		Mouse	PMID:18950615
Cellular Component	GO:0005604	basement membrane	Tnc	IDA		Mouse	PMID:9013311
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	IDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TNC	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tnc	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tnc	IDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tnc	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tnc	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0031012	extracellular matrix	Tnc	IDA		Rat	PMID:7519614|RGD:634489
Cellular Component	GO:0005576	extracellular region	TNC	HDA		Human	PMID:27068509
Cellular Component	GO:0005576	extracellular region	Tnc	IDA		Mouse	PMID:8856503
Cellular Component	GO:0005615	extracellular space	TNC	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	TNC	HDA		Human	PMID:20551380
Cellular Component	GO:0005925	focal adhesion	TNC	HDA		Human	PMID:21423176
Cellular Component	GO:0005614	interstitial matrix	Tnc	IDA		Mouse	PMID:11767049
Cellular Component	GO:0016020	membrane	TNC	HDA		Human	PMID:16210410
Cellular Component	GO:0098966	perisynaptic extracellular matrix	Tnc	IDA		Mouse	PMID:16452087
Cellular Component	GO:0098966	perisynaptic extracellular matrix	Tnc	EXP		Mouse	PMID:16452087
Cellular Component	GO:0090733	tenascin complex	Tnc	IPI		Mouse	MGI:MGI:3028459|PMID:14709716
Biological Process	GO:0007411	axon guidance	tncb	IMP	ZFIN:ZDB-MRPHLNO-101025-5	Zfish	PMID:12867507
Biological Process	GO:0014814	axon regeneration at neuromuscular junction	tncb	IMP	ZFIN:ZDB-MRPHLNO-110729-6	Zfish	PMID:21443931
Biological Process	GO:0007413	axonal fasciculation	tncb	IMP	ZFIN:ZDB-MRPHLNO-051111-1	Zfish	PMID:16110513
Biological Process	GO:0007413	axonal fasciculation	tncb	IMP	ZFIN:ZDB-MRPHLNO-051111-2	Zfish	PMID:16110513
Biological Process	GO:0060447	bud outgrowth involved in lung branching	Tnc	IMP		Rat	PMID:16928692|RGD:4889612
Biological Process	GO:0071799	cellular response to prostaglandin D stimulus	Tnc	IEP		Rat	PMID:10502285|RGD:4889620
Biological Process	GO:0071300	cellular response to retinoic acid	Tnc	IEP		Rat	PMID:10502285|RGD:4889620
Biological Process	GO:0071305	cellular response to vitamin D	Tnc	IEP		Rat	PMID:10502285|RGD:4889620
Biological Process	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	Tnc	IMP	MGI:MGI:2148540	Mouse	PMID:18950615
Biological Process	GO:0007498	mesoderm development	tncb	IEP		Zfish	PMID:8568519
Biological Process	GO:0002009	morphogenesis of an epithelium	Tnc	IMP		Mouse	MGI:MGI:3832136|PMID:18950615
Biological Process	GO:0030517	negative regulation of axon extension	tncb	IMP		Zfish	PMID:16110513
Biological Process	GO:0007162	negative regulation of cell adhesion	Tnc	IDA		Rat	PMID:7519614|RGD:634489
Biological Process	GO:0001755	neural crest cell migration	tncb	IEP		Zfish	PMID:8568519
Biological Process	GO:0007528	neuromuscular junction development	Tnc	IMP	MGI:MGI:2148540	Mouse	PMID:9593587
Biological Process	GO:0031175	neuron projection development	Tnc	IMP		Rat	PMID:19403822|RGD:4889608
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Tnc	IEP		Rat	PMID:12971948|RGD:4889616
Biological Process	GO:0021554	optic nerve development	tncb	IMP	ZFIN:ZDB-MRPHLNO-101025-5	Zfish	PMID:12867507
Biological Process	GO:0001649	osteoblast differentiation	TNC	HDA		Human	PMID:16210410
Biological Process	GO:0014012	peripheral nervous system axon regeneration	Tnc	IMP	MGI:MGI:2388370	Mouse	PMID:16262655
Biological Process	GO:0048680	positive regulation of axon regeneration	tncb	IMP	ZFIN:ZDB-MRPHLNO-110729-6	Zfish	PMID:21443931
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tnc	IDA		Mouse	PMID:19690384
Biological Process	GO:0010628	positive regulation of gene expression	Tnc	IMP		Mouse	MGI:MGI:4359548|PMID:19690384
Biological Process	GO:0010628	positive regulation of gene expression	Tnc	IDA		Mouse	PMID:19690384
Biological Process	GO:0045887	positive regulation of synaptic assembly at neuromuscular junction	tncb	IMP	ZFIN:ZDB-MRPHLNO-110729-6	Zfish	PMID:21443931
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	Tnc	IMP	MGI:MGI:2148540	Mouse	PMID:18950615
Biological Process	GO:0030155	regulation of cell adhesion	TNC	IDA		Human	PMID:11731446
Biological Process	GO:0001558	regulation of cell growth	TNC	IDA		Human	PMID:11731446
Biological Process	GO:0050727	regulation of inflammatory response	Tnc	IMP		Mouse	MGI:MGI:6828675|PMID:10594729
Biological Process	GO:0045471	response to ethanol	Tnc	IEP		Rat	PMID:15565633|RGD:4889614
Biological Process	GO:0071774	response to fibroblast growth factor	Tnc	IEP		Rat	PMID:12060805|RGD:4889617
Biological Process	GO:0009612	response to mechanical stimulus	Tnc	IEP		Rat	PMID:19541731|RGD:4889601
Biological Process	GO:0009611	response to wounding	TNC	IDA		Human	PMID:16891397
Biological Process	GO:0009611	response to wounding	TNC	IEP		Human	PMID:16891397
Biological Process	GO:0042060	wound healing	Tnc	IEP		Rat	PMID:19541731|RGD:4889601

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern