Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNF
  • Mouse genes Tnf
  • Rat genes Tnf
  • Zfish genes tnfa,tnfb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	TNF	IDA		Human	PMID:10748004
Molecular Function	GO:0005125	cytokine activity	Tnf	IDA		Mouse	PMID:27830702
Molecular Function	GO:0005125	cytokine activity	Tnf	IDA		Mouse	PMID:11588035
Molecular Function	GO:0005125	cytokine activity	Tnf	IDA		Mouse	PMID:11894098
Molecular Function	GO:0038177	death receptor agonist activity	TNF	IDA		Human	PMID:10748004
Molecular Function	GO:0042802	identical protein binding	TNF	IDA		Human	PMID:14512626
Molecular Function	GO:0042802	identical protein binding	TNF	IPI	UniProtKB:P01375	Human	PMID:19838188
Molecular Function	GO:0042802	identical protein binding	TNF	IPI	UniProtKB:P01375	Human	PMID:23815148
Molecular Function	GO:0042802	identical protein binding	TNF	IPI	UniProtKB:P01375	Human	PMID:2922050
Molecular Function	GO:0002020	protease binding	TNF	IPI	UniProtKB:P78325	Human	PMID:12777399
Molecular Function	GO:0002020	protease binding	Tnf	IPI	UniProtKB:Q05910	Mouse	MGI:MGI:4942254|PMID:12135759
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8UYL3	Human	PMID:11878931
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:12887920
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P20333	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8UYL3	Human	PMID:17681535
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9DHW0	Human	PMID:19838188
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:20080539
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:20103630
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P26651	Human	PMID:21784977
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:22028622
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9Y6K9	Human	PMID:23032186
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9Y6K9	Human	PMID:23104095
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:23955153
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:24070898
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P20333	Human	PMID:24070898
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:25911380
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O88351	Human	PMID:26649818
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O89110	Human	PMID:26649818
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P25118	Human	PMID:26649818
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q3U0V2	Human	PMID:26649818
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q60769	Human	PMID:26649818
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q60855	Human	PMID:26649818
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P19438	Human	PMID:2848815
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9Y6K9	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O14863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O43300	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O75459	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P00387	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q15849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q16585	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q53GL0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q6NSX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q6PEW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q6UXG8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q6ZMZ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8IUN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8IYJ2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8N386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8N4L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8N6L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8WV48	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q92482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q96RD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9BXK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9H7M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:Q9HC36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNF	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tnf	IPI	UniProtKB:Q9QWL7	Mouse	MGI:MGI:3624581|PMID:16702408
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TNF	IDA		Human	PMID:17350185
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	TNF	IDA		Human	PMID:14512626
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	TNF	IPI	UniProtKB:P19438|UniProtKB:P20333	Human	PMID:9435233
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	Tnf	IDA		Mouse	PMID:11588035
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	Tnf	IPI	PR:P25118	Mouse	PMID:1645445
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	Tnf	IPI	PR:P25119	Mouse	PMID:1645445
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	Tnf	IDA		Rat	PMID:12376316|RGD:628388
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	Tnf	IPI	RGD:621237	Rat	PMID:20649583|RGD:5130976
Cellular Component	GO:0009986	cell surface	TNF	IDA		Human	PMID:18355445
Cellular Component	GO:0005737	cytoplasm	Tnf	IDA		Rat	PMID:15602748|RGD:1582142
Cellular Component	GO:0009897	external side of plasma membrane	Tnf	IDA		Mouse	MGI:MGI:3610792|PMID:16282525
Cellular Component	GO:0009897	external side of plasma membrane	Tnf	IDA		Mouse	PMID:21606376
Cellular Component	GO:0009897	external side of plasma membrane	Tnf	IDA		Rat	PMID:12622907|RGD:1598936
Cellular Component	GO:0005576	extracellular region	Tnf	IDA		Rat	PMID:12364855|RGD:152176658
Cellular Component	GO:0005615	extracellular space	TNF	IDA		Human	PMID:23552949
Cellular Component	GO:0005615	extracellular space	TNF	IDA		Human	PMID:10443688
Cellular Component	GO:0005615	extracellular space	TNF	IDA		Human	PMID:12594207
Cellular Component	GO:0005615	extracellular space	TNF	IDA		Human	PMID:18355445
Cellular Component	GO:0005615	extracellular space	TNF	IDA		Human	PMID:21323571
Cellular Component	GO:0005615	extracellular space	TNF	IDA		Human	PMID:3932069
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:27830702
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:24740015
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:12855817
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:11728336
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:10549626
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:11168643
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:12872135
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:15220916
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:14764707
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:25084278
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:16275384
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:10545106
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:15843532
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:18261938
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:16236719
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:11894098
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:10899905
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:17693256
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:23892723
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:1577194
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:16239543
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Mouse	PMID:18997793
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Rat	PMID:16269520|RGD:1580205
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Rat	PMID:16525716|RGD:14985246
Cellular Component	GO:0005615	extracellular space	Tnf	IDA		Rat	PMID:19472295|RGD:8693643
Cellular Component	GO:0005615	extracellular space	tnfa	IMP		Zfish	PMID:25416946
Cellular Component	GO:0005622	intracellular anatomical structure	Tnf	IDA		Mouse	PMID:19723499
Cellular Component	GO:0045121	membrane raft	TNF	IDA		Human	PMID:17010968
Cellular Component	GO:0045121	membrane raft	Tnf	IDA		Mouse	MGI:MGI:3828392|PMID:17010968
Cellular Component	GO:0043025	neuronal cell body	Tnf	IDA		Rat	PMID:11412877|RGD:13825263
Cellular Component	GO:0001891	phagocytic cup	Tnf	IDA		Mouse	MGI:MGI:3610792|PMID:16282525
Cellular Component	GO:0005886	plasma membrane	TNF	IDA		Human	PMID:18355445
Cellular Component	GO:0005886	plasma membrane	Tnf	IDA		Mouse	PMID:15155767
Cellular Component	GO:0055037	recycling endosome	Tnf	IDA		Mouse	MGI:MGI:3610792|PMID:16282525
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	TNF	IDA		Human	PMID:16723520
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	Tnf	IDA		Mouse	PMID:16183742
Biological Process	GO:0002526	acute inflammatory response	Tnf	IEP		Rat	PMID:24028507|RGD:10755447
Biological Process	GO:0009887	animal organ morphogenesis	Tnf	IMP	MGI:MGI:2149024	Mouse	PMID:8879212
Biological Process	GO:0140374	antiviral innate immune response	TNF	IDA		Human	PMID:11773383
Biological Process	GO:0006915	apoptotic process	Tnf	IDA		Rat	PMID:12077131|RGD:625484
Biological Process	GO:0097190	apoptotic signaling pathway	Tnf	IDA		Mouse	PMID:15629131
Biological Process	GO:0097190	apoptotic signaling pathway	Tnf	IDA		Mouse	PMID:8208546
Biological Process	GO:0006914	autophagy	tnfa	IMP	ZFIN:ZDB-MRPHLNO-110621-1	Zfish	PMID:27351838
Biological Process	GO:0019722	calcium-mediated signaling	Tnf	IDA		Rat	PMID:12077131|RGD:625484
Biological Process	GO:0001775	cell activation	Tnf	IDA		Rat	PMID:12626358|RGD:1580298
Biological Process	GO:0045123	cellular extravasation	Tnf	IDA		Mouse	PMID:10528208
Biological Process	GO:0071230	cellular response to amino acid stimulus	Tnf	IDA		Mouse	PMID:20548288
Biological Process	GO:1904646	cellular response to amyloid-beta	Tnf	IEP		Rat	PMID:19004508|RGD:13825252
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IMP		Mouse	MGI:MGI:7387167|PMID:29849090
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IDA		Mouse	PMID:20060382
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IDA		Mouse	PMID:19047410
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IDA		Mouse	PMID:21606371
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IEP		Rat	PMID:10959811|RGD:14994703
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IEP		Rat	PMID:15602748|RGD:1582142
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnf	IMP		Rat	PMID:17964727|RGD:14995441
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	Tnf	IEP		Rat	PMID:1580332|RGD:38508902
Biological Process	GO:0071316	cellular response to nicotine	TNF	IDA		Human	PMID:18676776
Biological Process	GO:0071407	cellular response to organic cyclic compound	TNF	IDA		Human	PMID:21147091
Biological Process	GO:0071300	cellular response to retinoic acid	Tnf	IEP		Rat	PMID:15602748|RGD:1582142
Biological Process	GO:0097237	cellular response to toxic substance	Tnf	IEP		Rat	PMID:9292703|RGD:14994704
Biological Process	GO:0071346	cellular response to type II interferon	Tnf	IMP		Mouse	MGI:MGI:7387167|PMID:29849090
Biological Process	GO:0071346	cellular response to type II interferon	Tnf	IEP		Rat	PMID:16525716|RGD:14985246
Biological Process	GO:0002439	chronic inflammatory response to antigenic stimulus	TNF	IMP		Human	PMID:14512626
Biological Process	GO:0007623	circadian rhythm	Tnf	IEP		Rat	PMID:9483199|RGD:11552588
Biological Process	GO:0030866	cortical actin cytoskeleton organization	TNF	IDA		Human	PMID:25816133
Biological Process	GO:0006952	defense response	Tnf	IMP	MGI:MGI:1861040	Mouse	PMID:8395024
Biological Process	GO:0006952	defense response	Tnf	IMP	MGI:MGI:1860250	Mouse	PMID:9223320
Biological Process	GO:0042742	defense response to bacterium	Tnf	IDA		Mouse	PMID:10899905
Biological Process	GO:0042742	defense response to bacterium	tnfa	IDA		Zfish	PMID:29572872
Biological Process	GO:0042742	defense response to bacterium	tnfb	IDA		Zfish	PMID:29572872
Biological Process	GO:0042742	defense response to bacterium	tnfa	IDA		Zfish	PMID:19047404
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Tnf	IGI	MGI:MGI:104797	Mouse	PMID:9834074
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	Tnf	IMP		Rat	PMID:16675114|RGD:7387300
Biological Process	GO:0048566	embryonic digestive tract development	TNF	IEP		Human	PMID:20875417
Biological Process	GO:0072577	endothelial cell apoptotic process	Tnf	IDA		Mouse	MGI:MGI:5796069|PMID:26808574
Biological Process	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	Tnf	IDA		Mouse	PMID:11241200
Biological Process	GO:0030198	extracellular matrix organization	Tnf	IDA		Mouse	PMID:15381731
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	TNF	IDA		Human	PMID:11577081
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	TNF	IDA		Human	PMID:16611992
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Tnf	IGI	MGI:MGI:108212	Mouse	PMID:19498109
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Tnf	IGI	MGI:MGI:1261423	Mouse	PMID:22089168
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Tnf	IGI	MGI:MGI:104798	Mouse	PMID:22089168
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	TNF	IDA		Human	PMID:10521396
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	TNF	IDA		Human	PMID:18202225
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	TNF	IDA		Human	PMID:18676776
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Tnf	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Tnf	IGI	MGI:MGI:1096330	Mouse	PMID:12431371
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Tnf	IGI	MGI:MGI:1928487	Mouse	PMID:20080598
Biological Process	GO:0031101	fin regeneration	tnfa	IMP	ZFIN:ZDB-MRPHLNO-171010-5	Zfish	PMID:28796253
Biological Process	GO:0006006	glucose metabolic process	Tnf	IDA		Mouse	PMID:12068289
Biological Process	GO:0006959	humoral immune response	Tnf	IMP	MGI:MGI:2149024	Mouse	PMID:8879212
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Tnf	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Tnf	IDA		Mouse	PMID:12867038
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Tnf	IDA		Mouse	PMID:16260493
Biological Process	GO:0006955	immune response	tnfb	IDA		Zfish	PMID:29572872
Biological Process	GO:0006955	immune response	tnfa	IDA		Zfish	PMID:29572872
Biological Process	GO:0006955	immune response	tnfa	IDA		Zfish	PMID:15752547
Biological Process	GO:0006954	inflammatory response	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0006954	inflammatory response	TNF	IDA		Human	PMID:21147091
Biological Process	GO:0006954	inflammatory response	TNF	IDA		Human	PMID:22267480
Biological Process	GO:0006954	inflammatory response	Tnf	IGI	MGI:MGI:2687194	Mouse	PMID:21148126
Biological Process	GO:0006954	inflammatory response	Tnf	IGI	MGI:MGI:893592	Mouse	PMID:21148126
Biological Process	GO:0006954	inflammatory response	tnfa	IGI	ZFIN:ZDB-GENO-150617-6,ZFIN:ZDB-MRPHLNO-110621-1	Zfish	PMID:25730872
Biological Process	GO:0090594	inflammatory response to wounding	Tnf	IDA		Mouse	PMID:27830702
Biological Process	GO:0032635	interleukin-6 production	Tnf	IDA		Mouse	PMID:11894098
Biological Process	GO:0060729	intestinal epithelial structure maintenance	tnfa	IGI	ZFIN:ZDB-GENO-150617-6,ZFIN:ZDB-MRPHLNO-110621-1	Zfish	PMID:25730872
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Tnf	IDA		Mouse	PMID:17242187
Biological Process	GO:0007254	JNK cascade	Tnf	IDA		Mouse	PMID:20080598
Biological Process	GO:0007254	JNK cascade	Tnf	IDA		Mouse	PMID:16260493
Biological Process	GO:0007254	JNK cascade	Tnf	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0007254	JNK cascade	Tnf	IGI	MGI:MGI:1341850	Mouse	PMID:17015619
Biological Process	GO:0050900	leukocyte migration	Tnf	IDA		Mouse	PMID:15034066
Biological Process	GO:0002523	leukocyte migration involved in inflammatory response	Tnf	IEP		Rat	PMID:27939985|RGD:15036816
Biological Process	GO:0050901	leukocyte tethering or rolling	TNF	IDA		Human	PMID:10820279
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	TNF	IDA		Human	PMID:21147091
Biological Process	GO:0001889	liver development	tnfa	IMP	ZFIN:ZDB-MRPHLNO-171212-1	Zfish	PMID:27366683
Biological Process	GO:0001889	liver development	tnfa	IMP	ZFIN:ZDB-MRPHLNO-110301-5	Zfish	PMID:21064033
Biological Process	GO:0001889	liver development	tnfb	IMP	ZFIN:ZDB-MRPHLNO-110301-6	Zfish	PMID:21064033
Biological Process	GO:0097421	liver regeneration	Tnf	IEP		Rat	PMID:9178702|RGD:14995465
Biological Process	GO:0002281	macrophage activation involved in immune response	Tnf	IMP		Mouse	MGI:MGI:7387167|PMID:29849090
Biological Process	GO:0000165	MAPK cascade	TNF	IMP		Human	PMID:21147091
Biological Process	GO:0001774	microglial cell activation	Tnf	IDA		Mouse	MGI:MGI:6274957|PMID:22950459
Biological Process	GO:0007275	multicellular organism development	Tnf	IMP	MGI:MGI:1860953	Mouse	PMID:9368616
Biological Process	GO:0097527	necroptotic signaling pathway	TNF	IDA		Human	PMID:11101870
Biological Process	GO:0097527	necroptotic signaling pathway	TNF	IDA		Human	PMID:22265413
Biological Process	GO:0097527	necroptotic signaling pathway	TNF	IDA		Human	PMID:22265414
Biological Process	GO:0097527	necroptotic signaling pathway	TNF	IDA		Human	PMID:22817896
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:108212	Mouse	PMID:21052097
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:1261423	Mouse	PMID:22037414
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:108212	Mouse	PMID:19498109
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:1346877	Mouse	PMID:21052097
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:1336166	Mouse	PMID:21368763
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:1261423	Mouse	PMID:21368763
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:2154952	Mouse	PMID:21368763
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:2154952	Mouse	PMID:19498109
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:1197009	Mouse	PMID:21052097
Biological Process	GO:0097527	necroptotic signaling pathway	Tnf	IGI	MGI:MGI:1921506	Mouse	PMID:22037414
Biological Process	GO:0010693	negative regulation of alkaline phosphatase activity	Tnf	IDA		Mouse	MGI:MGI:5285024|PMID:21689636
Biological Process	GO:1900222	negative regulation of amyloid-beta clearance	Tnf	IGI	UniProtKB:P01580,UniProtKB:P15261	Mouse	MGI:MGI:3697769|PMID:17255335
Biological Process	GO:0043066	negative regulation of apoptotic process	Tnf	IDA		Rat	PMID:9395232|RGD:14696805
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	TNF	IGI	RNAcentral:URS0000330617_9606	Human	PMID:31124343
Biological Process	GO:1903347	negative regulation of bicellular tight junction assembly	TNF	IDA		Human	PMID:25816133
Biological Process	GO:0120190	negative regulation of bile acid secretion	Tnf	IDA		Rat	PMID:12563244|RGD:14995483
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	TNF	IDA		Human	PMID:22499991
Biological Process	GO:0061048	negative regulation of branching involved in lung morphogenesis	TNF	IDA		Human	PMID:17350185
Biological Process	GO:0008285	negative regulation of cell population proliferation	Tnf	IDA		Rat	PMID:15476580|RGD:1580212
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	TNF	IGI	RNAcentral:URS0000330617_9606	Human	PMID:31124343
Biological Process	GO:0002719	negative regulation of cytokine production involved in immune response	TNF	IDA		Human	PMID:10443688
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TNF	IDA		Human	PMID:16895791
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TNF	IDA		Human	PMID:17350185
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	Tnf	IDA		Mouse	MGI:MGI:5796069|PMID:26808574
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	TNF	IDA		Human	PMID:10666185
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Tnf	IDA		Rat	PMID:10757205|RGD:13825251
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:22499991
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:20164187
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:31124343
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:31824476
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:15345745
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:22267480
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IGI	UniProtKB:Q16539	Human	PMID:24299952
Biological Process	GO:0010629	negative regulation of gene expression	TNF	IDA		Human	PMID:26371161
Biological Process	GO:0010629	negative regulation of gene expression	Tnf	IDA		Mouse	PMID:26427354
Biological Process	GO:0046325	negative regulation of glucose import	Tnf	IDA		Mouse	PMID:12068289
Biological Process	GO:0046325	negative regulation of glucose import	Tnf	IDA		Rat	PMID:14764603|RGD:1580214
Biological Process	GO:0010459	negative regulation of heart rate	Tnf	IMP		Rat	PMID:7875478|RGD:14975128
Biological Process	GO:0032715	negative regulation of interleukin-6 production	TNF	IDA		Human	PMID:10443688
Biological Process	GO:0002037	negative regulation of L-glutamate import across plasma membrane	Tnf	IDA		Rat	PMID:15713255|RGD:1580210
Biological Process	GO:0050995	negative regulation of lipid catabolic process	TNF	IDA		Human	PMID:19032770
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	Tnf	IDA		Mouse	MGI:MGI:5796069|PMID:26808574
Biological Process	GO:0031642	negative regulation of myelination	Tnf	IMP		Rat	PMID:23982745|RGD:10450590
Biological Process	GO:0045662	negative regulation of myoblast differentiation	Tnf	IMP		Mouse	PMID:23844157
Biological Process	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	TNF	IDA		Human	PMID:25816133
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Tnf	IDA		Mouse	MGI:MGI:5285024|PMID:21689636
Biological Process	GO:0090324	negative regulation of oxidative phosphorylation	Tnf	IDA		Rat	PMID:8903396|RGD:14995471
Biological Process	GO:0043242	negative regulation of protein-containing complex disassembly	TNF	IDA		Human	PMID:17389591
Biological Process	GO:2000272	negative regulation of signaling receptor activity	TNF	IDA		Human	PMID:10443688
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	Tnf	IMP		Rat	PMID:7875478|RGD:14975128
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TNF	IDA		Human	PMID:1618860
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TNF	IDA		Human	PMID:15345745
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Tnf	IDA		Mouse	MGI:MGI:5285024|PMID:21689636
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Tnf	IDA		Mouse	PMID:9305915
Biological Process	GO:0061044	negative regulation of vascular wound healing	TNF	IDA		Human	PMID:22499991
Biological Process	GO:0045071	negative regulation of viral genome replication	TNF	IDA		Human	PMID:10490959
Biological Process	GO:0038061	NIK/NF-kappaB signaling	tnfa	IMP		Zfish	PMID:25416946
Biological Process	GO:0030316	osteoclast differentiation	Tnf	IGI	MGI:MGI:99484	Mouse	PMID:15485831
Biological Process	GO:0030316	osteoclast differentiation	Tnf	IGI	MGI:MGI:1100089	Mouse	PMID:15485831
Biological Process	GO:0032292	peripheral nervous system axon ensheathment	tnfa	IMP	ZFIN:ZDB-MRPHLNO-110621-1	Zfish	PMID:28379965
Biological Process	GO:0045760	positive regulation of action potential	Tnf	IDA		Rat	PMID:12684490|RGD:7421501
Biological Process	GO:1902004	positive regulation of amyloid-beta formation	Tnf	IDA		Mouse	MGI:MGI:3697769|PMID:17255335
Biological Process	GO:0043065	positive regulation of apoptotic process	TNF	IDA		Human	PMID:16723520
Biological Process	GO:0043065	positive regulation of apoptotic process	TNF	IDA		Human	PMID:17389591
Biological Process	GO:0043065	positive regulation of apoptotic process	TNF	IDA		Human	PMID:22173242
Biological Process	GO:0043065	positive regulation of apoptotic process	TNF	IMP		Human	PMID:9343261
Biological Process	GO:0043065	positive regulation of apoptotic process	Tnf	IMP		Rat	PMID:16269520|RGD:1580205
Biological Process	GO:0043065	positive regulation of apoptotic process	Tnf	IMP		Rat	PMID:24598936|RGD:10450586
Biological Process	GO:2000334	positive regulation of blood microparticle formation	TNF	IDA		Human	PMID:24998411
Biological Process	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	TNF	IDA		Human	PMID:1690216
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	TNF	IDA		Human	PMID:16803872
Biological Process	GO:0045785	positive regulation of cell adhesion	TNF	IMP		Human	PMID:23892569
Biological Process	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	TNF	IDA		Human	PMID:20551324
Biological Process	GO:0032722	positive regulation of chemokine production	TNF	IDA		Human	PMID:10490959
Biological Process	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	Tnf	IGI	MGI:MGI:104797	Mouse	PMID:9834074
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	TNF	IDA		Human	PMID:11577081
Biological Process	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Tnf	IMP		Rat	PMID:12131680|RGD:14995454
Biological Process	GO:0001819	positive regulation of cytokine production	TNF	IDA		Human	PMID:10443688
Biological Process	GO:0001819	positive regulation of cytokine production	TNF	IDA		Human	PMID:17922812
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	TNF	IDA		Human	PMID:31824476
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	TNF	IGI	RNAcentral:URS00004DA9DB_9606	Human	PMID:23608026
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	Tnf	IDA		Rat	PMID:9395232|RGD:14696805
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TNF	IDA		Human	PMID:14512626
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TNF	IDA		Human	PMID:17350185
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tnf	IDA		Mouse	PMID:12761567
Biological Process	GO:0031622	positive regulation of fever generation	Tnf	IDA		Mouse	MGI:MGI:4413614|PMID:19940926
Biological Process	GO:0032724	positive regulation of fractalkine production	Tnf	IDA		Rat	PMID:12729461|RGD:13673777
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:25327529
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:28159925
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:31824476
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:23608026
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:11085990
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IMP		Human	PMID:16203728
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:21559518
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:22267480
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:22952837
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:23817958
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IMP		Human	PMID:23892569
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IGI	RNAcentral:URS00001C770D_9606	Human	PMID:24299952
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:24998411
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:26371161
Biological Process	GO:0010628	positive regulation of gene expression	TNF	IDA		Human	PMID:31124343
Biological Process	GO:0010628	positive regulation of gene expression	Tnf	IDA		Mouse	MGI:MGI:3697769|PMID:17255335
Biological Process	GO:0010628	positive regulation of gene expression	Tnf	IDA		Mouse	MGI:MGI:6272248|PMID:18941241
Biological Process	GO:0010628	positive regulation of gene expression	Tnf	IDA		Rat	PMID:25158758|RGD:10054077
Biological Process	GO:0010628	positive regulation of gene expression	Tnf	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:0010628	positive regulation of gene expression	Tnf	IMP		Rat	PMID:9111198|RGD:14995469
Biological Process	GO:0060252	positive regulation of glial cell proliferation	TNF	IGI	UniProtKB:P01584	Human	PMID:1752215
Biological Process	GO:0060252	positive regulation of glial cell proliferation	TNF	IDA		Human	PMID:2104886
Biological Process	GO:0051798	positive regulation of hair follicle development	Tnf	IMP		Mouse	MGI:MGI:3624581|PMID:16702408
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	tnfa	IMP	ZFIN:ZDB-MRPHLNO-110621-1	Zfish	PMID:25416946
Biological Process	GO:2000347	positive regulation of hepatocyte proliferation	Tnf	IDA		Rat	PMID:17557910|RGD:14995481
Biological Process	GO:2000347	positive regulation of hepatocyte proliferation	Tnf	IMP		Rat	PMID:9111198|RGD:14995469
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	TNF	IDA		Human	PMID:10604883
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	TNF	IDA		Human	PMID:20551324
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	Tnf	IDA		Mouse	MGI:MGI:5796069|PMID:26808574
Biological Process	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	Tnf	IGI	MGI:MGI:104797	Mouse	PMID:9834074
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TNF	IDA		Human	PMID:15310755
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TNF	IDA		Human	PMID:17922812
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tnf	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tnf	IDA		Mouse	PMID:22089168
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tnf	IDA		Mouse	PMID:16260493
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tnf	IDA		Mouse	PMID:12867038
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tnf	IGI	RGD:3171	Rat	PMID:12631113|RGD:1580306
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tnf	IDA		Rat	PMID:12729461|RGD:13673777
Biological Process	GO:1903721	positive regulation of I-kappaB phosphorylation	TNF	IDA		Human	PMID:31124343
Biological Process	GO:0050729	positive regulation of inflammatory response	Tnf	IMP		Rat	PMID:16269520|RGD:1580205
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	TNF	IDA		Human	PMID:31124343
Biological Process	GO:0032741	positive regulation of interleukin-18 production	Tnf	IMP		Rat	PMID:16269520|RGD:1580205
Biological Process	GO:0150129	positive regulation of interleukin-33 production	TNF	IDA		Human	PMID:31824476
Biological Process	GO:0032755	positive regulation of interleukin-6 production	TNF	IDA		Human	PMID:24299952
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tnf	IDA		Mouse	PMID:11894098
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tnf	IMP		Rat	PMID:10454827|RGD:14985258
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Tnf	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TNF	IDA		Human	PMID:23608026
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TNF	IGI	RNAcentral:URS00004DA9DB_9606	Human	PMID:23608026
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TNF	IDA		Human	PMID:31824476
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TNF	IDA		Human	PMID:20551324
Biological Process	GO:0032757	positive regulation of interleukin-8 production	TNF	IMP		Human	PMID:24790089
Biological Process	GO:0046330	positive regulation of JNK cascade	Tnf	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0046330	positive regulation of JNK cascade	Tnf	IDA		Mouse	PMID:20080598
Biological Process	GO:0046330	positive regulation of JNK cascade	Tnf	IDA		Mouse	PMID:16260493
Biological Process	GO:0043507	positive regulation of JUN kinase activity	TNF	IDA		Human	PMID:17389591
Biological Process	GO:1904999	positive regulation of leukocyte adhesion to arterial endothelial cell	TNF	IDA		Human	PMID:22267480
Biological Process	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	TNF	IDA		Human	PMID:26371161
Biological Process	GO:0043406	positive regulation of MAP kinase activity	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0043406	positive regulation of MAP kinase activity	TNF	IDA		Human	PMID:12813029
Biological Process	GO:0043406	positive regulation of MAP kinase activity	TNF	IDA		Human	PMID:17389591
Biological Process	GO:0043406	positive regulation of MAP kinase activity	TNF	IDA		Human	PMID:18440775
Biological Process	GO:0043410	positive regulation of MAPK cascade	TNF	IDA		Human	PMID:15310755
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	TNF	IDA		Human	PMID:18373975
Biological Process	GO:1902895	positive regulation of miRNA transcription	TNF	IDA		Human	PMID:22499991
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	Tnf	IMP		Rat	PMID:12713870|RGD:1580297
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Tnf	IDA		Mouse	MGI:MGI:6274957|PMID:22950459
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Tnf	IMP		Rat	PMID:14999074|RGD:1580294
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Tnf	IMP		Rat	PMID:23262920|RGD:10450589
Biological Process	GO:1902565	positive regulation of neutrophil activation	Tnf	IMP		Rat	PMID:8283134|RGD:14995443
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:15790681
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:10383454
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:11374864
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:16280327
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:16611992
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:20551324
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IMP		Human	PMID:24790089
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TNF	IDA		Human	PMID:25193116
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Tnf	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TNF	IDA		Human	PMID:31124343
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TNF	IDA		Human	PMID:17922812
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TNF	IDA		Human	PMID:20041225
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Tnf	IMP		Mouse	MGI:MGI:5285024|PMID:21689636
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	TNF	IDA		Human	PMID:8383325
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	Tnf	IMP		Rat	PMID:9537427|RGD:14985259
Biological Process	GO:0051173	positive regulation of nitrogen compound metabolic process	Tnf	IGI	ComplexPortal:CPX-1062,UniProtKB:P01579|ComplexPortal:CPX-1062,UniProtKB:P01580	Mouse	MGI:MGI:6305053|PMID:7715705
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	TNF	IDA		Human	PMID:17888176
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	TNF	IDA		Human	PMID:17389591
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	TNF	IDA		Human	PMID:18440775
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	Tnf	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:0050766	positive regulation of phagocytosis	TNF	IMP		Human	PMID:18201371
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Tnf	IMP		Rat	PMID:12729461|RGD:13673777
Biological Process	GO:0071803	positive regulation of podosome assembly	TNF	IDA		Human	PMID:15220135
Biological Process	GO:0043068	positive regulation of programmed cell death	TNF	IDA		Human	PMID:16611992
Biological Process	GO:0045732	positive regulation of protein catabolic process	TNF	IDA		Human	PMID:18632959
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Tnf	IDA		Mouse	PMID:20080598
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Tnf	IMP		Rat	PMID:12729461|RGD:13673777
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	TNF	IDA		Human	PMID:19366699
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	Tnf	IMP		Mouse	MGI:MGI:6202006|PMID:16547515
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	Tnf	IMP		Rat	PMID:11910117|RGD:1580308
Biological Process	GO:0001934	positive regulation of protein phosphorylation	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0001934	positive regulation of protein phosphorylation	TNF	IDA		Human	PMID:16723520
Biological Process	GO:0001934	positive regulation of protein phosphorylation	TNF	IDA		Human	PMID:17389591
Biological Process	GO:0051222	positive regulation of protein transport	TNF	IDA		Human	PMID:15310755
Biological Process	GO:0051222	positive regulation of protein transport	Tnf	IDA		Rat	PMID:12118012|RGD:1580307
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	TNF	IDA		Human	PMID:12813029
Biological Process	GO:0043243	positive regulation of protein-containing complex disassembly	TNF	IDA		Human	PMID:12813029
Biological Process	GO:0043243	positive regulation of protein-containing complex disassembly	TNF	IDA		Human	PMID:17389591
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	Tnf	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	TNF	IDA		Human	PMID:16518841
Biological Process	GO:1901671	positive regulation of superoxide dismutase activity	TNF	IDA		Human	PMID:22836756
Biological Process	GO:0050806	positive regulation of synaptic transmission	Tnf	IMP		Mouse	MGI:MGI:6202006|PMID:16547515
Biological Process	GO:0050806	positive regulation of synaptic transmission	Tnf	IMP		Rat	PMID:11910117|RGD:1580308
Biological Process	GO:1901647	positive regulation of synoviocyte proliferation	TNF	IDA		Human	PMID:31124343
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TNF	IGI	UniProtKB:Q8K120	Human	PMID:16803872
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TNF	IDA		Human	PMID:15345745
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TNF	IDA		Human	PMID:20551324
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tnf	IDA		Mouse	PMID:19404405
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tnf	IGI	MGI:MGI:107656	Mouse	PMID:18025219
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tnf	IDA		Mouse	PMID:9305915
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tnf	IDA		Mouse	PMID:17670746
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tnf	IDA		Rat	PMID:12729461|RGD:13673777
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tnf	IMP		Rat	PMID:9834372|RGD:14688051
Biological Process	GO:0045994	positive regulation of translational initiation by iron	Tnf	IDA		Mouse	PMID:11588035
Biological Process	GO:0032729	positive regulation of type II interferon production	Tnf	IGI	MGI:MGI:104797	Mouse	PMID:9834074
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	Tnf	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	Tnf	IDA		Mouse	MGI:MGI:5796069|PMID:26808574
Biological Process	GO:0060557	positive regulation of vitamin D biosynthetic process	TNF	IDA		Human	PMID:1690216
Biological Process	GO:0070207	protein homotrimerization	tnfa	IPI	UniProtKB:Q6T9C7	Zfish	PMID:33989682
Biological Process	GO:0043491	protein kinase B signaling	TNF	IMP		Human	PMID:21147091
Biological Process	GO:0043491	protein kinase B signaling	Tnf	IDA		Mouse	PMID:20080598
Biological Process	GO:0072659	protein localization to plasma membrane	TNF	IDA		Human	PMID:25816133
Biological Process	GO:0031099	regeneration	tnfa	IMP	ZFIN:ZDB-MRPHLNO-090428-3	Zfish	PMID:23575850
Biological Process	GO:0060693	regulation of branching involved in salivary gland morphogenesis	Tnf	IMP		Mouse	PMID:11241200
Biological Process	GO:0060693	regulation of branching involved in salivary gland morphogenesis	Tnf	IDA		Mouse	PMID:11241200
Biological Process	GO:0042127	regulation of cell population proliferation	Tnf	IDA		Mouse	PMID:11799106
Biological Process	GO:0042127	regulation of cell population proliferation	Tnf	IDA		Rat	PMID:10757205|RGD:13825251
Biological Process	GO:2000351	regulation of endothelial cell apoptotic process	TNF	IMP		Human	PMID:10843670
Biological Process	GO:1903140	regulation of establishment of endothelial barrier	TNF	IDA		Human	PMID:25816133
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	TNF	IDA		Human	PMID:10748004
Biological Process	GO:0002637	regulation of immunoglobulin production	Tnf	IDA		Mouse	PMID:12958312
Biological Process	GO:0050727	regulation of inflammatory response	Tnf	IDA		Mouse	PMID:24349514
Biological Process	GO:0050796	regulation of insulin secretion	TNF	IDA		Human	PMID:8383325
Biological Process	GO:0045670	regulation of osteoclast differentiation	Tnf	IDA		Mouse	PMID:12490655
Biological Process	GO:0001932	regulation of protein phosphorylation	Tnf	IDA		Mouse	PMID:15169905
Biological Process	GO:0001932	regulation of protein phosphorylation	Tnf	IDA		Mouse	PMID:24349514
Biological Process	GO:0050708	regulation of protein secretion	Tnf	IDA		Mouse	PMID:19293336
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Tnf	IDA		Mouse	PMID:21052097
Biological Process	GO:0050807	regulation of synapse organization	Tnf	IMP		Mouse	MGI:MGI:6202006|PMID:16547515
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Tnf	IDA		Rat	PMID:12729461|RGD:13673777
Biological Process	GO:1905242	response to 3,3',5-triiodo-L-thyronine	Tnf	IEP		Rat	PMID:15019085|RGD:14995431
Biological Process	GO:0014823	response to activity	Tnf	IEP		Rat	PMID:20007518|RGD:4144081
Biological Process	GO:0046685	response to arsenic-containing substance	tnfa	IDA		Zfish	PMID:17400579
Biological Process	GO:0046685	response to arsenic-containing substance	tnfa	IDA		Zfish	PMID:16007375
Biological Process	GO:0009617	response to bacterium	Tnf	IEP		Rat	PMID:8769813|RGD:14995453
Biological Process	GO:0009617	response to bacterium	tnfa	IDA		Zfish	PMID:17400579
Biological Process	GO:0009617	response to bacterium	tnfa	IDA		Zfish	PMID:17804254
Biological Process	GO:0045471	response to ethanol	Tnf	IEP		Rat	PMID:27939985|RGD:15036816
Biological Process	GO:0043330	response to exogenous dsRNA	tnfa	IDA		Zfish	PMID:19201835
Biological Process	GO:0009750	response to fructose	Tnf	IEP		Rat	PMID:12364855|RGD:152176658
Biological Process	GO:0051384	response to glucocorticoid	TNF	IDA		Human	PMID:10443688
Biological Process	GO:1990268	response to gold nanoparticle	Tnf	IEP		Rat	PMID:23150627|RGD:7815044
Biological Process	GO:0140460	response to Gram-negative bacterium	Tnf	IEP		Rat	PMID:9466473|RGD:38508904
Biological Process	GO:0001666	response to hypoxia	Tnf	IEP		Rat	PMID:15197744|RGD:4143218
Biological Process	GO:0035900	response to isolation stress	Tnf	IEP		Rat	PMID:33411841|RGD:152998999
Biological Process	GO:1902065	response to L-glutamate	Tnf	IDA		Rat	PMID:15713255|RGD:1580210
Biological Process	GO:0032496	response to lipopolysaccharide	Tnf	IEP		Rat	PMID:11096136|RGD:8548521
Biological Process	GO:0032496	response to lipopolysaccharide	Tnf	IMP		Rat	PMID:25158758|RGD:10054077
Biological Process	GO:0032496	response to lipopolysaccharide	tnfa	IDA		Zfish	PMID:19201835
Biological Process	GO:0032496	response to lipopolysaccharide	tnfa	IDA		Zfish	PMID:17442590
Biological Process	GO:0036005	response to macrophage colony-stimulating factor	Tnf	IEP		Rat	PMID:24882100|RGD:151667420
Biological Process	GO:0009612	response to mechanical stimulus	Tnf	IEP		Rat	PMID:11834488|RGD:1598418
Biological Process	GO:0002237	response to molecule of bacterial origin	tnfa	IDA		Zfish	PMID:19201835
Biological Process	GO:0031667	response to nutrient levels	Tnf	IEP		Rat	PMID:17904344|RGD:38508905
Biological Process	GO:0014070	response to organic cyclic compound	Tnf	IEP		Rat	PMID:27939985|RGD:15036816
Biological Process	GO:0010033	response to organic substance	Tnf	IDA		Mouse	PMID:17475835
Biological Process	GO:1901554	response to paracetamol	Tnf	IEP		Rat	PMID:10378475|RGD:14994702
Biological Process	GO:0009314	response to radiation	Tnf	IEP		Rat	PMID:20458900|RGD:7394736
Biological Process	GO:0009615	response to virus	TNF	IDA		Human	PMID:10490959
Biological Process	GO:0009615	response to virus	tnfa	IMP	ZFIN:ZDB-MRPHLNO-110621-1	Zfish	PMID:27351838
Biological Process	GO:0009615	response to virus	tnfa	IDA		Zfish	PMID:25746990
Biological Process	GO:0009615	response to virus	tnfa	IDA		Zfish	PMID:17371995
Biological Process	GO:0009615	response to virus	tnfa	IDA		Zfish	PMID:16007375
Biological Process	GO:0009410	response to xenobiotic stimulus	Tnf	IEP		Rat	PMID:19925291|RGD:2315112
Biological Process	GO:0009410	response to xenobiotic stimulus	Tnf	IEP		Rat	PMID:29091898|RGD:15090820
Biological Process	GO:0030730	sequestering of triglyceride	TNF	IDA		Human	PMID:19032770
Biological Process	GO:0007165	signal transduction	Tnf	IDA		Rat	PMID:12077131|RGD:625484
Biological Process	GO:0003009	skeletal muscle contraction	Tnf	IEP		Rat	PMID:20007518|RGD:4144081
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway	Tnf	IMP		Rat	PMID:25158758|RGD:10054077
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	TNF	IMP		Human	PMID:10748004
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	TNF	IDA		Human	PMID:28159925
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	TNF	IDA		Human	PMID:31824476
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	Tnf	IDA		Mouse	PMID:3898078
Biological Process	GO:0032609	type II interferon production	Tnf	IGI	MGI:MGI:104797	Mouse	PMID:9834074
Biological Process	GO:0010573	vascular endothelial growth factor production	TNF	IDA		Human	PMID:12794819
Biological Process	GO:0042311	vasodilation	Tnf	IMP		Rat	PMID:16284227|RGD:1580206

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern