Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFAIP6
  • Mouse genes Tnfaip6
  • Rat genes Tnfaip6
  • Zfish genes tnfaip6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfaip6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	TNFAIP6	IDA		Human	PMID:26468290
Molecular Function	GO:0106435	carboxylesterase activity	TNFAIP6	IDA		Human	PMID:16873769
Molecular Function	GO:0106435	carboxylesterase activity	TNFAIP6	IDA		Human	PMID:20463016
Molecular Function	GO:0001968	fibronectin binding	TNFAIP6	IDA		Human	PMID:18042364
Molecular Function	GO:0005540	hyaluronic acid binding	TNFAIP6	IDA		Human	PMID:26468290
Molecular Function	GO:0005540	hyaluronic acid binding	TNFAIP6	IDA		Human	PMID:26823460
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P12643	Human	PMID:16771708
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P02751	Human	PMID:18042364
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:O14788	Human	PMID:18586671
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P12643:PRO_0000033825	Human	PMID:18586671
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P43026:PRO_0000033913	Human	PMID:18586671
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:Q6KF10:PRO_0000042253	Human	PMID:18586671
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P26022	Human	PMID:22267482
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P10145	Human	PMID:24501198
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P19827	Human	PMID:26468290
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:O14625:PRO_0000005106	Human	PMID:27044744
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P13500:PRO_0000005146	Human	PMID:27044744
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:P80098:PRO_0000005183	Human	PMID:27044744
Molecular Function	GO:0005515	protein binding	TNFAIP6	IPI	UniProtKB:Q99731:PRO_0000005214	Human	PMID:27044744
Cellular Component	GO:0005576	extracellular region	TNFAIP6	IDA		Human	PMID:1730767
Cellular Component	GO:0005615	extracellular space	Tnfaip6	IDA		Rat	PMID:22912904|RGD:7777188
Biological Process	GO:1905590	fibronectin fibril organization	TNFAIP6	IDA		Human	PMID:18042364
Biological Process	GO:0030212	hyaluronan metabolic process	TNFAIP6	IDA		Human	PMID:20463016
Biological Process	GO:0030212	hyaluronan metabolic process	TNFAIP6	IDA		Human	PMID:26468290
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	TNFAIP6	IDA		Human	PMID:16771708
Biological Process	GO:0050728	negative regulation of inflammatory response	TNFAIP6	IDA		Human	PMID:21569482
Biological Process	GO:0090024	negative regulation of neutrophil chemotaxis	TNFAIP6	IDA		Human	PMID:24501198
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	TNFAIP6	IDA		Human	PMID:16771708
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	TNFAIP6	IDA		Human	PMID:18586671
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	TNFAIP6	IDA		Human	PMID:18586671
Biological Process	GO:0001550	ovarian cumulus expansion	Tnfaip6	IMP		Mouse	MGI:MGI:6204879|PMID:26468290
Biological Process	GO:0030728	ovulation	Tnfaip6	IEP		Rat	PMID:11089543|RGD:7777189
Biological Process	GO:0030335	positive regulation of cell migration	Tnfaip6	IMP		Rat	PMID:22912904|RGD:7777188
Biological Process	GO:1903911	positive regulation of receptor clustering	TNFAIP6	IDA		Human	PMID:26823460

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern