Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFAIP8
  • Mouse genes Tnfaip8
  • Rat genes Tnfaip8
  • Zfish genes tnfaip8l1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfaip8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	TNFAIP8	IMP		Human	PMID:10644768
Molecular Function	GO:0140313	molecular sequestering activity	Tnfaip8	EXP		Mouse	MGI:MGI:7294457|PMID:28740220
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9NPJ6	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9H8W4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q8NBZ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q96CG3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9NPJ6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9NZ81	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q56P03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q86V38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q96JC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q96S99	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9NPJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFAIP8	IPI	UniProtKB:Q9NZ81	Human	PMID:32296183
Molecular Function	GO:0036094	small molecule binding	Tnfaip8	EXP		Mouse	MGI:MGI:7294457|PMID:28740220
Cellular Component	GO:0005737	cytoplasm	TNFAIP8	IDA		Human	PMID:14724590
Cellular Component	GO:0005654	nucleoplasm	TNFAIP8	IDA		Human	GO_REF:0000052
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Tnfaip8	IMP		Mouse	PMID:20824097
Biological Process	GO:0032611	interleukin-1 beta production	Tnfaip8	IMP		Mouse	PMID:20824097
Biological Process	GO:0043065	positive regulation of apoptotic process	TNFAIP8	IMP		Human	PMID:10644768

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern