Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D
  • Mouse genes Tnfrsf10b
  • Rat genes Tnfrsf10b
  • Zfish genes hdr,tnfrsfa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfrsf10b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TNFRSF10A	IDA		Human	PMID:19090789
Molecular Function	GO:0002020	protease binding	TNFRSF10A	IPI	UniProtKB:Q14790	Human	PMID:21785459
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q14790	Human	PMID:17047155
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q96P48	Human	PMID:18165900
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:P49841	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q13490	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:P50591	Human	PMID:19427028
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q14790	Human	PMID:19427028
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:P50591	Human	PMID:20103630
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q14790	Human	PMID:20103630
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q13158	Human	PMID:21785459
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q14790	Human	PMID:21785459
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q99497	Human	PMID:21785459
Molecular Function	GO:0005515	protein binding	TNFRSF10A	IPI	UniProtKB:Q08380	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:10549288
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P49840	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P49841	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:Q13158|UniProtKB:Q14790	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:Q13490	Human	PMID:18846110
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:19427028
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:20097879
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:20103630
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:21459798
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:21525171
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:21822306
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:22266862
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P50591	Human	PMID:23678861
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:Q12797-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10B	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:O14863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:O60883	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:O95279	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:P00387	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:P10620	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:P48051	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q13113	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q8WWH4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q96A49	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q96B21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q96KC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10C	IPI	UniProtKB:Q9Y676	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:A0A384ME17	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:C9JCN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:O43561-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:O95236-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:P09455	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:P49585	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:P53367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q05329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q5VYK3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q7Z6M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q8IWE2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q8IY26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q8WY91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q92504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q969Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q96LZ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9BT40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9BW92	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9H5X1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9HC62	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9NQG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9NTN9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9P2R7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9UGP5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF10D	IPI	UniProtKB:Q9UKF7-2	Human	PMID:32296183
Molecular Function	GO:0036463	TRAIL receptor activity	TNFRSF10B	IDA		Human	PMID:28362429
Cellular Component	GO:0009986	cell surface	TNFRSF10A	IDA		Human	PMID:22952982
Cellular Component	GO:0009986	cell surface	TNFRSF10B	IDA		Human	PMID:22952982
Cellular Component	GO:0005829	cytosol	TNFRSF10A	IDA		Human	PMID:22240897
Cellular Component	GO:0005794	Golgi apparatus	TNFRSF10A	IDA		Human	PMID:22240897
Cellular Component	GO:0016020	membrane	Tnfrsf10b	IDA		Rat	PMID:12490136|RGD:2290501
Cellular Component	GO:0045121	membrane raft	TNFRSF10A	IDA		Human	PMID:19090789
Cellular Component	GO:0005886	plasma membrane	TNFRSF10A	IDA		Human	PMID:22240897
Cellular Component	GO:0005886	plasma membrane	hdr	IDA		Zfish	PMID:10934476
Biological Process	GO:0071260	cellular response to mechanical stimulus	TNFRSF10A	IEP		Human	PMID:19593445
Biological Process	GO:0071260	cellular response to mechanical stimulus	TNFRSF10B	IEP		Human	PMID:19593445
Biological Process	GO:0002357	defense response to tumor cell	TNFRSF10B	IDA		Human	PMID:28362429
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	TNFRSF10A	IDA		Human	PMID:21785459
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Tnfrsf10b	IMP		Rat	PMID:19934367|RGD:4142856
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	TNFRSF10B	IMP		Human	PMID:15322075
Biological Process	GO:0008584	male gonad development	Tnfrsf10b	IEP		Rat	PMID:12021051|RGD:634235
Biological Process	GO:0043065	positive regulation of apoptotic process	tnfrsfa	IDA		Zfish	PMID:16888647
Biological Process	GO:0043065	positive regulation of apoptotic process	hdr	IDA		Zfish	PMID:16888647
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	hdr	IMP	ZFIN:ZDB-MRPHLNO-060215-5	Zfish	PMID:16413388
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TNFRSF10B	IEP		Human	PMID:12761501
Biological Process	GO:0034976	response to endoplasmic reticulum stress	TNFRSF10B	IDA		Human	PMID:15322075
Biological Process	GO:0014070	response to organic cyclic compound	Tnfrsf10b	IEP		Rat	PMID:12490136|RGD:2290501
Biological Process	GO:0010033	response to organic substance	Tnfrsf10b	IEP		Rat	PMID:17434926|RGD:2290499
Biological Process	GO:0036462	TRAIL-activated apoptotic signaling pathway	TNFRSF10A	IMP		Human	PMID:19090789
Biological Process	GO:0036462	TRAIL-activated apoptotic signaling pathway	TNFRSF10A	IDA		Human	PMID:21785459

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern