Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFRSF12A
  • Mouse genes Tnfrsf12a
  • Rat genes Tnfrsf12a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfrsf12a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q12933	Human	PMID:11728344
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q13077	Human	PMID:11728344
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q13114	Human	PMID:11728344
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q9BUZ4	Human	PMID:11728344
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q9Y4K3	Human	PMID:11728344
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q12933	Human	PMID:21525013
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q13490	Human	PMID:21525013
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:O43508	Human	PMID:23438059
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q9BRI3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q9BRI3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFRSF12A	IPI	UniProtKB:Q9BYR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tnfrsf12a	IPI	PR:P63001	Mouse	PMID:14573547
Cellular Component	GO:0009986	cell surface	Tnfrsf12a	IDA		Mouse	PMID:12821115
Cellular Component	GO:0005886	plasma membrane	Tnfrsf12a	IDA		Mouse	PMID:10551889
Cellular Component	GO:0001726	ruffle	Tnfrsf12a	IDA		Mouse	PMID:14573547
Biological Process	GO:0007155	cell adhesion	Tnfrsf12a	IDA		Mouse	PMID:10551889
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Tnfrsf12a	IDA		Mouse	PMID:12821115
Biological Process	GO:0043065	positive regulation of apoptotic process	TNFRSF12A	IDA		Human	PMID:21525013
Biological Process	GO:0045773	positive regulation of axon extension	Tnfrsf12a	IDA		Mouse	PMID:14573547
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	TNFRSF12A	IMP		Human	PMID:21525013
Biological Process	GO:0045765	regulation of angiogenesis	Tnfrsf12a	IDA		Mouse	MGI:MGI:5572898|PMID:11728344
Biological Process	GO:0061041	regulation of wound healing	TNFRSF12A	IDA		Human	PMID:11728344
Biological Process	GO:0006931	substrate-dependent cell migration, cell attachment to substrate	Tnfrsf12a	IDA		Mouse	PMID:10551889

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern