Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tnfrsf1b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TNFRSF1B
- Mouse genes Tnfrsf1b
- Rat genes Tnfrsf1b
- Zfish genes tnfrsf1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfrsf1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:P42224	Human	PMID:10848577
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:P37198	Human	PMID:11244088
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:P01375	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:Q12933	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:P01375	Human	PMID:24070898
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:P28799	Human	PMID:24070898
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:Q9NQH7	Human	PMID:25609706
Molecular Function	GO:0005515	protein binding	TNFRSF1B	IPI	UniProtKB:Q12933	Human	PMID:8069916
Molecular Function	GO:0005515	protein binding	Tnfrsf1b	IPI	PR:P11679	Mouse	PMID:10747083
Molecular Function	GO:0005515	protein binding	Tnfrsf1b	IPI	PR:P05784	Mouse	PMID:10747083
Molecular Function	GO:0043120	tumor necrosis factor binding	TNFRSF1B	IPI	UniProtKB:P01375	Human	PMID:9435233
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	Tnfrsf1b	IPI	UniProtKB:P06804	Mouse	PMID:1645445
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	Tnfrsf1b	IPI	UniProtKB:P01374	Mouse	PMID:1645445
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	Tnfrsf1b	IDA		Rat	PMID:12376316\|RGD:628388
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TNFRSF1B	IPI	UniProtKB:O94972	Human	PMID:11279055
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TNFRSF1B	IPI	UniProtKB:Q12933	Human	PMID:11279055
Cellular Component	GO:0030424	axon	Tnfrsf1b	IDA		Rat	PMID:11240015\|RGD:5130963
Cellular Component	GO:0016020	membrane	Tnfrsf1b	IDA		Mouse	PMID:10747083
Cellular Component	GO:0016020	membrane	Tnfrsf1b	IDA		Rat	PMID:12376316\|RGD:628388
Cellular Component	GO:0045121	membrane raft	TNFRSF1B	IDA		Human	PMID:17010968
Cellular Component	GO:0045121	membrane raft	Tnfrsf1b	IDA		Mouse	MGI:MGI:3828392\|PMID:17010968
Cellular Component	GO:0043025	neuronal cell body	Tnfrsf1b	IDA		Rat	PMID:20715153\|RGD:5130921
Cellular Component	GO:0005634	nucleus	Tnfrsf1b	IDA		Rat	PMID:11240015\|RGD:5130963
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Tnfrsf1b	IDA		Rat	PMID:20715153\|RGD:5130921
Cellular Component	GO:0005886	plasma membrane	tnfrsf1b	IMP		Zfish	PMID:25416946
Cellular Component	GO:0043196	varicosity	Tnfrsf1b	IDA		Rat	PMID:20715153\|RGD:5130921
Biological Process	GO:0007568	aging	Tnfrsf1b	IEP		Rat	PMID:22666474\|RGD:7245943
Biological Process	GO:0003176	aortic valve development	Tnfrsf1b	IGI	UniProtKB:P25118	Mouse	MGI:MGI:6158728\|PMID:26491108
Biological Process	GO:0007166	cell surface receptor signaling pathway	Tnfrsf1b	IMP	MGI:MGI:1860087	Mouse	PMID:9551933
Biological Process	GO:0071363	cellular response to growth factor stimulus	Tnfrsf1b	IEP		Rat	PMID:20715153\|RGD:5130921
Biological Process	GO:0071222	cellular response to lipopolysaccharide	TNFRSF1B	IMP		Human	PMID:22480688
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Tnfrsf1b	IEP		Rat	PMID:11324713\|RGD:13825430
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Tnfrsf1b	IMP	MGI:MGI:1857262	Mouse	PMID:7990930
Biological Process	GO:0150098	glial cell-neuron signaling	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:0006955	immune response	Tnfrsf1b	IDA		Rat	PMID:12376316\|RGD:628388
Biological Process	GO:0006954	inflammatory response	Tnfrsf1b	IMP	MGI:MGI:1860087	Mouse	PMID:9551933
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Tnfrsf1b	IMP		Mouse	PMID:17242187
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Tnfrsf1b	IGI	UniProtKB:P25118	Mouse	MGI:MGI:6158728\|PMID:26491108
Biological Process	GO:0060548	negative regulation of cell death	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:0003332	negative regulation of extracellular matrix constituent secretion	Tnfrsf1b	IGI	UniProtKB:P25118	Mouse	MGI:MGI:6158728\|PMID:26491108
Biological Process	GO:0050728	negative regulation of inflammatory response	Tnfrsf1b	IMP	MGI:MGI:1857262	Mouse	PMID:11588035
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:1901215	negative regulation of neuron death	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:0038061	NIK/NF-kappaB signaling	tnfrsf1b	IMP		Zfish	PMID:25416946
Biological Process	GO:0032292	peripheral nervous system axon ensheathment	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:28379965
Biological Process	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	Tnfrsf1b	IGI	UniProtKB:P25118	Mouse	MGI:MGI:6158728\|PMID:26491108
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-3	Zfish	PMID:25540193
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:25416946
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	TNFRSF1B	IMP		Human	PMID:22480688
Biological Process	GO:0031643	positive regulation of myelination	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:0003177	pulmonary valve development	Tnfrsf1b	IGI	UniProtKB:P25118	Mouse	MGI:MGI:6158728\|PMID:26491108
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	tnfrsf1b	IGI	ZFIN:ZDB-MRPHLNO-080808-7,ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:22956347
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:22956347
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	tnfrsf1b	IGI	ZFIN:ZDB-MRPHLNO-080808-6,ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:22956347
Biological Process	GO:0002718	regulation of cytokine production involved in immune response	Tnfrsf1b	IGI	UniProtKB:Q9Z0D9	Mouse	MGI:MGI:5888814\|PMID:28052249
Biological Process	GO:1901532	regulation of hematopoietic progenitor cell differentiation	tnfrsf1b	IGI	ZFIN:ZDB-GENE-040426-2227	Zfish	PMID:25540193
Biological Process	GO:0031641	regulation of myelination	Tnfrsf1b	IGI	UniProtKB:Q9Z0D9	Mouse	MGI:MGI:5888814\|PMID:28052249
Biological Process	GO:0150077	regulation of neuroinflammatory response	Tnfrsf1b	IGI	UniProtKB:Q9Z0D9	Mouse	MGI:MGI:5888814\|PMID:28052249
Biological Process	GO:2001141	regulation of RNA biosynthetic process	Tnfrsf1b	IMP		Mouse	MGI:MGI:5775216\|PMID:27147664
Biological Process	GO:0002724	regulation of T cell cytokine production	Tnfrsf1b	IMP		Mouse	MGI:MGI:5888814\|PMID:28052249
Biological Process	GO:0042129	regulation of T cell proliferation	Tnfrsf1b	IMP		Mouse	MGI:MGI:5888814\|PMID:28052249
Biological Process	GO:0032496	response to lipopolysaccharide	Tnfrsf1b	IEP		Rat	PMID:21195213\|RGD:5130879
Biological Process	GO:0009615	response to virus	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:27351838
Biological Process	GO:0050779	RNA destabilization	Tnfrsf1b	IMP	MGI:MGI:1857262	Mouse	PMID:11588035
Biological Process	GO:0001944	vasculature development	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-2	Zfish	PMID:22956347
Biological Process	GO:0001944	vasculature development	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-1	Zfish	PMID:22956347
Biological Process	GO:0001944	vasculature development	tnfrsf1b	IMP	ZFIN:ZDB-MRPHLNO-130620-3	Zfish	PMID:22956347

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.