Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFSF12,TNFSF12-TNFSF13
  • Mouse genes Tnfsf12
  • Rat genes Tnfsf12
  • Zfish genes tnfsf12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfsf12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:Q8N302	Human	PMID:14961121
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:Q6SIX7	Human	PMID:23438059
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:Q9NP84	Human	PMID:23438059
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:Q9UPY3	Human	PMID:29657270
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:P35638	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TNFSF12	IPI	UniProtKB:P06493	Human	PMID:32814053
Cellular Component	GO:0005576	extracellular region	Tnfsf12	IDA		Mouse	PMID:12821115
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TNFSF12	IDA		Human	PMID:14961121
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Tnfsf12	IDA		Mouse	PMID:12821115
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	TNFSF12	IDA		Human	PMID:21525013
Biological Process	GO:0045732	positive regulation of protein catabolic process	TNFSF12	IDA		Human	PMID:17389268

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern