Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNFSF18
  • Mouse genes Tnfsf18
  • Rat genes Tnfsf18
  • Zfish genes tnfsf18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnfsf18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TNFSF18	IPI	UniProtKB:Q9UNG2	Human	PMID:18040044
Molecular Function	GO:0042802	identical protein binding	TNFSF18	IPI	UniProtKB:Q9UNG2	Human	PMID:18378892
Molecular Function	GO:0042802	identical protein binding	Tnfsf18	IPI	UniProtKB:Q7TS55	Mouse	MGI:MGI:3772964|PMID:18182486
Molecular Function	GO:0042802	identical protein binding	Tnfsf18	IPI	UniProtKB:Q7TS55	Mouse	MGI:MGI:3772722|PMID:18178614
Molecular Function	GO:0005515	protein binding	TNFSF18	IPI	UniProtKB:Q9Y5U5	Human	PMID:18040044
Molecular Function	GO:0005515	protein binding	TNFSF18	IPI	UniProtKB:Q9Y5U5	Human	PMID:18378892
Molecular Function	GO:0005515	protein binding	TNFSF18	IPI	UniProtKB:Q2M3D2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tnfsf18	IPI	UniProtKB:O35714	Mouse	MGI:MGI:3772964|PMID:18182486
Molecular Function	GO:0005515	protein binding	Tnfsf18	IPI	UniProtKB:O35714	Mouse	MGI:MGI:3690151|PMID:14647196
Molecular Function	GO:0032813	tumor necrosis factor receptor superfamily binding	Tnfsf18	IDA		Mouse	MGI:MGI:5306317|PMID:14521928
Cellular Component	GO:0009986	cell surface	Tnfsf18	IDA		Mouse	MGI:MGI:5306317|PMID:14521928
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	tnfsf18	IMP	ZFIN:ZDB-MRPHLNO-101109-4	Zfish	PMID:19598108
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	tnfsf18	IMP	ZFIN:ZDB-MRPHLNO-101109-3	Zfish	PMID:19598108
Biological Process	GO:2000329	negative regulation of T-helper 17 cell lineage commitment	Tnfsf18	IMP		Mouse	MGI:MGI:5551556|PMID:24107315
Biological Process	GO:0045785	positive regulation of cell adhesion	TNFSF18	IMP	UniProtKB:Q9Y5U5	Human	PMID:23892569
Biological Process	GO:0045785	positive regulation of cell adhesion	Tnfsf18	IMP	UniProtKB:O35714	Mouse	MGI:MGI:5634881|PMID:23892569
Biological Process	GO:0050729	positive regulation of inflammatory response	Tnfsf18	IMP		Mouse	MGI:MGI:5551556|PMID:24107315
Biological Process	GO:0002687	positive regulation of leukocyte migration	TNFSF18	IMP	UniProtKB:Q9Y5U5	Human	PMID:23892569
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	Tnfsf18	IMP		Mouse	MGI:MGI:5551556|PMID:24107315
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	Tnfsf18	IMP		Mouse	MGI:MGI:5551556|PMID:24107315
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Tnfsf18	IMP		Mouse	MGI:MGI:5306317|PMID:14521928
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	TNFSF18	IMP	UniProtKB:Q9Y5U5	Human	PMID:23892569
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	tnfsf18	IMP	ZFIN:ZDB-MRPHLNO-101109-3	Zfish	PMID:19598108
Biological Process	GO:2000508	regulation of dendritic cell chemotaxis	Tnfsf18	IMP		Mouse	MGI:MGI:5551556|PMID:24107315
Biological Process	GO:0043254	regulation of protein-containing complex assembly	Tnfsf18	IMP		Mouse	MGI:MGI:5551556|PMID:24107315
Biological Process	GO:0042129	regulation of T cell proliferation	Tnfsf18	IDA		Mouse	MGI:MGI:2682525|PMID:14608036
Biological Process	GO:0002309	T cell proliferation involved in immune response	Tnfsf18	IDA		Mouse	MGI:MGI:2682525|PMID:14608036
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	Tnfsf18	IMP		Mouse	MGI:MGI:5306317|PMID:14521928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern