Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNIP2
  • Mouse genes Tnip2
  • Rat genes Tnip2
  • Zfish genes tnip2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnip2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	TNIP2	IDA		Human	PMID:18212736
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q15831	Human	PMID:12595760
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q15831	Human	PMID:12753905
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q9Y6K9	Human	PMID:14653779
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P41279	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q04864	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P19838-1	Human	PMID:15169888
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P21580	Human	PMID:15169888
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P41279	Human	PMID:15169888
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P21580	Human	PMID:15474016
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P19838	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q9Y6K9	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P19838	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P41279	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q04864	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P21580	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:Q9Y6K9	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	TNIP2	IPI	UniProtKB:P19838	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Tnip2	IPI	PR:Q02858	Mouse	PMID:20060382
Molecular Function	GO:0005515	protein binding	Tnip2	IPI	PR:Q60769	Mouse	PMID:11390377
Molecular Function	GO:0019901	protein kinase binding	TNIP2	IDA		Human	PMID:21784860
Cellular Component	GO:0005737	cytoplasm	Tnip2	IDA		Mouse	PMID:11390377
Cellular Component	GO:0005829	cytosol	TNIP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TNIP2	IDA		Human	GO_REF:0000052
Biological Process	GO:0023035	CD40 signaling pathway	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Tnip2	IDA		Mouse	PMID:11390377
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	TNIP2	IDA		Human	PMID:12933576
Biological Process	GO:0050871	positive regulation of B cell activation	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TNIP2	IDA		Human	PMID:21784860
Biological Process	GO:0043032	positive regulation of macrophage activation	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TNIP2	IDA		Human	PMID:12753905
Biological Process	GO:0050821	protein stabilization	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0034134	toll-like receptor 2 signaling pathway	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345
Biological Process	GO:0034162	toll-like receptor 9 signaling pathway	Tnip2	IMP		Mouse	MGI:MGI:3656197|PMID:16633345

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern