Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNKS2
  • Mouse genes Tnks2
  • Rat genes Tnks2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnks2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	TNKS2	IPI	UniProtKB:Q9NWT6	Human	PMID:21251231
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	TNKS2	IDA		Human	PMID:19759537
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	TNKS2	IDA		Human	PMID:21478859
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	TNKS2	IDA		Human	PMID:11739745
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	TNKS2	IDA		Human	PMID:25043379
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9C0C2	Human	PMID:11854288
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P14652	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P54274	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q13698	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q14980	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9BZL4	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9C0C2	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9UIQ6	Human	PMID:12080061
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:O15169	Human	PMID:19759537
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9Y2T1	Human	PMID:19759537
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NWT6	Human	PMID:21251231
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:O15169	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:O15234	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9H2G9	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9Y2T1	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P78314	Human	PMID:22153076
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q06649	Human	PMID:22153076
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:O15169	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:O43815	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P11274	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P14652	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P54274	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P78314	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q06649	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q13698	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q14980	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q6V0I7	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q92698	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9BZL4	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9C0C2	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NRI5	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NWV8	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9UIQ6	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:O15084	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q7Z6K5-1	Human	PMID:26774128
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NWT6	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NWT6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NWV8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	TNKS2	IPI	UniProtKB:P14652	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	Tnks2	IPI	RGD:727803	Rat	PMID:27441654|RGD:13628742
Cellular Component	GO:0005737	cytoplasm	TNKS2	IDA		Human	PMID:11278563
Cellular Component	GO:0005635	nuclear envelope	TNKS2	IDA		Human	PMID:11454873
Cellular Component	GO:0005634	nucleus	TNKS2	IDA		Human	PMID:11739745
Cellular Component	GO:0000242	pericentriolar material	TNKS2	IDA		Human	PMID:11454873
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TNKS2	IDA		Human	PMID:11454873
Biological Process	GO:0035264	multicellular organism growth	Tnks2	IMP	MGI:MGI:3621819	Mouse	PMID:16507985
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	TNKS2	IMP		Human	PMID:25939383
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	TNKS2	IMP		Human	PMID:19759537
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	TNKS2	IMP		Human	PMID:25939383
Biological Process	GO:1904355	positive regulation of telomere capping	TNKS2	IDA		Human	PMID:21531765
Biological Process	GO:1904355	positive regulation of telomere capping	TNKS2	IMP		Human	PMID:25939383
Biological Process	GO:0070213	protein auto-ADP-ribosylation	TNKS2	IDA		Human	PMID:21478859
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	TNKS2	IMP		Human	PMID:11739745
Biological Process	GO:0070212	protein poly-ADP-ribosylation	TNKS2	IDA		Human	PMID:25043379
Biological Process	GO:0000209	protein polyubiquitination	TNKS2	IDA		Human	PMID:19759537
Biological Process	GO:0000209	protein polyubiquitination	TNKS2	IDA		Human	PMID:21478859
Biological Process	GO:0040014	regulation of multicellular organism growth	Tnks2	IMP	MGI:MGI:3621924	Mouse	PMID:16507984

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern