Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNNC2
  • Mouse genes Tnnc2
  • Rat genes Tnnc2
  • Zfish genes tnnc2.1,tnnc2.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnnc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	TNNC2	IDA		Human	PMID:17194691
Molecular Function	GO:0005515	protein binding	TNNC2	IPI	UniProtKB:Q6FGX2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TNNC2	IPI	UniProtKB:P19429	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TNNC2	IPI	UniProtKB:Q86TI0	Human	PMID:32296183
Cellular Component	GO:0005861	troponin complex	TNNC2	IDA		Human	PMID:17194691
Biological Process	GO:0014823	response to activity	tnnc2.2	IDA		Zfish	PMID:16966387
Biological Process	GO:0003009	skeletal muscle contraction	TNNC2	IDA		Human	PMID:17194691

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern