Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNNT3
  • Mouse genes Tnnt3
  • Rat genes Tnnt3
  • Zfish genes tnnt3a,tnnt3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tnnt3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	TNNT3	IDA		Human	PMID:17194691
Molecular Function	GO:0048306	calcium-dependent protein binding	TNNT3	IDA		Human	PMID:8987992
Molecular Function	GO:0005523	tropomyosin binding	TNNT3	IDA		Human	PMID:9724539
Molecular Function	GO:0005523	tropomyosin binding	TNNT3	IMP		Human	PMID:8987992
Molecular Function	GO:0030172	troponin C binding	TNNT3	IPI	UniProtKB:P02586	Human	PMID:8987992
Molecular Function	GO:0030172	troponin C binding	TNNT3	IPI	UniProtKB:P02586	Human	PMID:9724539
Molecular Function	GO:0031013	troponin I binding	TNNT3	IPI	UniProtKB:P02643	Human	PMID:15507453
Molecular Function	GO:0031013	troponin I binding	TNNT3	IPI	UniProtKB:P48788	Human	PMID:17194691
Molecular Function	GO:0031013	troponin I binding	TNNT3	IPI	UniProtKB:P02586	Human	PMID:8987992
Cellular Component	GO:0005861	troponin complex	TNNT3	IDA		Human	PMID:17194691
Cellular Component	GO:0005861	troponin complex	TNNT3	IDA		Human	PMID:8987992
Cellular Component	GO:0005861	troponin complex	TNNT3	IDA		Human	PMID:9724539
Cellular Component	GO:0005861	troponin complex	Tnnt3	IDA		Rat	PMID:16192301|RGD:1599030
Biological Process	GO:0030239	myofibril assembly	tnnt3a	IMP	ZFIN:ZDB-MRPHLNO-110228-3	Zfish	PMID:21245197
Biological Process	GO:0030239	myofibril assembly	tnnt3b	IMP	ZFIN:ZDB-MRPHLNO-110228-4	Zfish	PMID:21245197
Biological Process	GO:1903612	positive regulation of calcium-dependent ATPase activity	TNNT3	IDA		Human	PMID:8987992
Biological Process	GO:1903612	positive regulation of calcium-dependent ATPase activity	TNNT3	IDA		Human	PMID:9724539
Biological Process	GO:0043462	regulation of ATP-dependent activity	TNNT3	IDA		Human	PMID:17194691
Biological Process	GO:0006937	regulation of muscle contraction	Tnnt3	IDA		Rat	PMID:16192301|RGD:1599030
Biological Process	GO:0006942	regulation of striated muscle contraction	TNNT3	IDA		Human	PMID:17194691
Biological Process	GO:0006942	regulation of striated muscle contraction	Tnnt3	IMP		Rat	PMID:16839517|RGD:1599483
Biological Process	GO:0045214	sarcomere organization	tnnt3a	IGI	ZFIN:ZDB-MRPHLNO-110228-1,ZFIN:ZDB-MRPHLNO-110228-3,ZFIN:ZDB-MRPHLNO-110228-4	Zfish	PMID:21245197
Biological Process	GO:0045214	sarcomere organization	tnnt3a	IMP	ZFIN:ZDB-MRPHLNO-110228-3	Zfish	PMID:21245197
Biological Process	GO:0045214	sarcomere organization	tnnt3b	IMP	ZFIN:ZDB-MRPHLNO-110228-4	Zfish	PMID:21245197
Biological Process	GO:0045214	sarcomere organization	tnnt3b	IGI	ZFIN:ZDB-MRPHLNO-110228-1,ZFIN:ZDB-MRPHLNO-110228-3,ZFIN:ZDB-MRPHLNO-110228-4	Zfish	PMID:21245197
Biological Process	GO:0003009	skeletal muscle contraction	TNNT3	IDA		Human	PMID:17194691

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern