Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TNS3
  • Mouse genes Tns3
  • Rat genes Tns3
  • Zfish genes tns3.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tns3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005091	guanyl-nucleotide exchange factor adaptor activity	Tns3	IDA		Mouse	PMID:27505886
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P21860	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:Q96QB1	Human	PMID:17190795
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P12830	Human	PMID:19732724
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P12931	Human	PMID:19732724
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P56945	Human	PMID:19732724
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:Q05397	Human	PMID:19732724
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	TNS3	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Tns3	IPI	PR:B2RY04	Mouse	PMID:27505886
Molecular Function	GO:0005515	protein binding	Tns3	IPI	PR:O54890	Mouse	PMID:27505886
Cellular Component	GO:0005829	cytosol	TNS3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	TNS3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	TNS3	HDA		Human	PMID:21423176
Cellular Component	GO:0002102	podosome	Tns3	IDA		Mouse	PMID:27505886
Biological Process	GO:0045453	bone resorption	Tns3	IMP		Mouse	PMID:27505886
Biological Process	GO:0008283	cell population proliferation	Tns3	IMP	MGI:MGI:3574415	Mouse	PMID:15733665
Biological Process	GO:0043542	endothelial cell migration	Tns3	IMP	MGI:MGI:3574415	Mouse	PMID:15733665
Biological Process	GO:0048286	lung alveolus development	Tns3	IMP	MGI:MGI:3574415	Mouse	PMID:15733665
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Tns3	IMP		Mouse	PMID:27505886
Biological Process	GO:0071800	podosome assembly	Tns3	IMP		Mouse	PMID:27505886
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tns3	IMP	MGI:MGI:3574415	Mouse	PMID:15733665
Biological Process	GO:1905099	positive regulation of guanyl-nucleotide exchange factor activity	Tns3	IDA		Mouse	PMID:27505886
Biological Process	GO:0035022	positive regulation of Rac protein signal transduction	Tns3	IPI	PR:B2RY04	Mouse	PMID:27505886

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern