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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tob1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tob1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:A5YKK6HumanPMID:18377426
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:O75175HumanPMID:18377426
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q13148HumanPMID:18377426
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q96LI5HumanPMID:18377426
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q9UIV1HumanPMID:18377426
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q9UIV1HumanPMID:19276069
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:P11940HumanPMID:20595394
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q9UIV1HumanPMID:20595394
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q17RY0HumanPMID:21336257
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q8NE35HumanPMID:21336257
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q9UIV1HumanPMID:21336257
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:A5YKK6HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:O75175HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q96LI5HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q9UIV1HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q9UIV1HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:P06396HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:P22607HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:Q13148HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingTOB1IPIUniProtKB:P11940HumanPMID:35044719
Molecular FunctionGO:0005515protein bindingTob1IPIUniProtKB:P57737MouseMGI:MGI:4936782|PMID:21130766
Molecular FunctionGO:0005515protein bindingTob1IPIPR:P97471MousePMID:11163184
Molecular FunctionGO:0005515protein bindingTob1IPIPR:P70340MousePMID:11163184
Molecular FunctionGO:0005515protein bindingTob1IPIPR:Q9JIW5MousePMID:11163184
Molecular FunctionGO:0005515protein bindingTob1IPIPR:P97454MousePMID:11163184
Molecular FunctionGO:0005515protein bindingtob1aIPIRefSeq:NP_058049ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIRefSeq:NP_001036125ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIZFIN:ZDB-GENE-030128-4ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIRefSeq:NP_032565ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIRefSeq:NP_032566ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIZFIN:ZDB-GENE-000509-3ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIZFIN:ZDB-GENE-040426-2575ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIRefSeq:NP_032568ZfishPMID:16890162
Molecular FunctionGO:0005515protein bindingtob1aIPIRefSeq:NP_034884ZfishPMID:16890162
Molecular FunctionGO:0030971receptor tyrosine kinase bindingTOB1IDAHumanPMID:8632892
Molecular FunctionGO:0046332SMAD bindingTob1IDAMousePMID:11163184
Molecular FunctionGO:0003714transcription corepressor activityTob1IDAMousePMID:11163184
Molecular FunctionGO:0140416transcription regulator inhibitor activitytob1aIMPZFIN:ZDB-MRPHLNO-071205-3ZfishPMID:16890162
Molecular FunctionGO:0140416transcription regulator inhibitor activitytob1aIGIZFIN:ZDB-GENE-040426-2575ZfishPMID:16890162
Cellular ComponentGO:0030014CCR4-NOT complexTOB1IDAHumanPMID:21336257
Cellular ComponentGO:0005737cytoplasmTob1IDAMousePMID:11163184
Cellular ComponentGO:0005737cytoplasmtob1aIDAZfishPMID:16890162
Cellular ComponentGO:0005634nucleustob1aIDAZfishPMID:16890162
Biological ProcessGO:0030509BMP signaling pathwaytob1aIDAZfishPMID:16890162
Biological ProcessGO:0009953dorsal/ventral pattern formationtob1aIMPZFIN:ZDB-MRPHLNO-071205-3ZfishPMID:16890162
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayTob1IDAMousePMID:11163184
Biological ProcessGO:0008285negative regulation of cell population proliferationTOB1IDAHumanPMID:19276069
Biological ProcessGO:0008285negative regulation of cell population proliferationTOB1IDAHumanPMID:8632892
Biological ProcessGO:0060212negative regulation of nuclear-transcribed mRNA poly(A) tail shorteningTOB1IDAHumanPMID:18377426
Biological ProcessGO:0045668negative regulation of osteoblast differentiationTob1IMPMGI:MGI:1933294MousePMID:11163184
Biological ProcessGO:0017148negative regulation of translationTOB1IDAHumanPMID:23236473
Biological ProcessGO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayTOB1IDAHumanPMID:21336257
Biological ProcessGO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shorteningTOB1IDAHumanPMID:21336257
Biological ProcessGO:0060390regulation of SMAD protein signal transductionTob1IDAMousePMID:11163184

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory