Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOB2
  • Mouse genes Tob2
  • Rat genes Tob2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tob2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	Tob2	IPI	PR:P48281	Mouse	PMID:18358842
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q60809	Human	PMID:19838187
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:P11940	Human	PMID:23340509
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q60809	Human	PMID:23340509
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:O14503	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q8TAP6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q9UFF9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q9UIV1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q9UIV1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:Q9UIV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOB2	IPI	UniProtKB:P11940	Human	PMID:35044719
Cellular Component	GO:0005829	cytosol	TOB2	IDA		Human	GO_REF:0000052
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Tob2	IMP	MGI:MGI:3789484	Mouse	PMID:18358842
Biological Process	GO:0030316	osteoclast differentiation	Tob2	IMP	MGI:MGI:3789484	Mouse	PMID:18358842
Biological Process	GO:0045778	positive regulation of ossification	Tob2	IMP	MGI:MGI:3789484	Mouse	PMID:18358842
Biological Process	GO:0010468	regulation of gene expression	Tob2	IMP	MGI:MGI:3789484	Mouse	PMID:18358842

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern