Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC51,LRTOMT,TOMT
  • Mouse genes Tomt
  • Rat genes Lrtomt
  • Zfish genes tomt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tomt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016206	catechol O-methyltransferase activity	Tomt	IDA		Mouse	MGI:MGI:3799635|PMID:18794526
Molecular Function	GO:0005515	protein binding	Tomt	IPI	UniProtKB:Q8R4P5	Mouse	MGI:MGI:6119970|PMID:28534737
Molecular Function	GO:0005515	protein binding	Tomt	IPI	UniProtKB:Q4KL25|UniProtKB:Q8K467|UniProtKB:Q8R4P4|UniProtKB:Q8R4P5|UniProtKB:Q99PJ1	Mouse	MGI:MGI:6100205|PMID:28504928
Cellular Component	GO:0045177	apical part of cell	Tomt	IDA		Mouse	MGI:MGI:6100205|PMID:28504928
Cellular Component	GO:0016323	basolateral plasma membrane	tomt	IDA		Zfish	PMID:28534737|ZFIN:ZDB-PUB-170524-6
Cellular Component	GO:0005737	cytoplasm	Tomt	IDA		Mouse	MGI:MGI:6100205|PMID:28504928
Cellular Component	GO:0005783	endoplasmic reticulum	Tomt	IDA		Mouse	MGI:MGI:6100205|PMID:28504928
Cellular Component	GO:0005783	endoplasmic reticulum	tomt	IDA		Zfish	PMID:28534737|ZFIN:ZDB-PUB-170524-6
Cellular Component	GO:0005794	Golgi apparatus	tomt	IDA		Zfish	PMID:28534737|ZFIN:ZDB-PUB-170524-6
Biological Process	GO:0031223	auditory behavior	tomt	IMP		Zfish	PMID:28534737|ZFIN:ZDB-PUB-170524-6
Biological Process	GO:0060117	auditory receptor cell development	Tomt	IMP		Mouse	MGI:MGI:3799635|PMID:18794526
Biological Process	GO:0042424	catecholamine catabolic process	Tomt	IDA		Mouse	MGI:MGI:3799635|PMID:18794526
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	tomt	IMP	ZFIN:ZDB-GENO-010427-5	Zfish	PMID:9491988
Biological Process	GO:0006897	endocytosis	tomt	IMP		Zfish	PMID:10526320
Biological Process	GO:0035315	hair cell differentiation	tomt	IMP		Zfish	PMID:10526320
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	tomt	IMP	ZFIN:ZDB-GENO-170823-8	Zfish	PMID:28534737
Biological Process	GO:0048884	neuromast development	tomt	IMP	ZFIN:ZDB-GENO-010427-5	Zfish	PMID:9491988
Biological Process	GO:1904591	positive regulation of protein import	Tomt	IMP		Mouse	MGI:MGI:6100205|PMID:28504928
Biological Process	GO:0007605	sensory perception of sound	Tomt	IMP		Mouse	MGI:MGI:3799635|PMID:18794526
Biological Process	GO:0007605	sensory perception of sound	Tomt	IMP		Mouse	MGI:MGI:6100205|PMID:28504928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern