Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOR1A
  • Mouse genes Tor1a
  • Rat genes Tor1a
  • Zfish genes tor1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tor1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	TOR1A	IDA		Human	PMID:23569223
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	TOR1A	IDA		Human	PMID:15505207
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	TOR1A	IMP		Human	PMID:24930953
Molecular Function	GO:0008092	cytoskeletal protein binding	TOR1A	IPI	UniProtKB:P08670	Human	PMID:16361107
Molecular Function	GO:0008092	cytoskeletal protein binding	TOR1A	IPI	UniProtKB:P08670	Human	PMID:18827015
Molecular Function	GO:0008092	cytoskeletal protein binding	TOR1A	IPI	UniProtKB:Q15149	Human	PMID:18827015
Molecular Function	GO:0008092	cytoskeletal protein binding	Tor1a	IPI	UniProtKB:P20152|UniProtKB:Q9QXS1	Mouse	MGI:MGI:3814961|PMID:18827015
Molecular Function	GO:0042802	identical protein binding	TOR1A	IPI	UniProtKB:O14656	Human	PMID:20015956
Molecular Function	GO:0042802	identical protein binding	TOR1A	IMP		Human	PMID:24930953
Molecular Function	GO:0042802	identical protein binding	Tor1a	IPI	PR:Q9ER39	Mouse	PMID:20015956
Molecular Function	GO:0019894	kinesin binding	TOR1A	IPI	UniProtKB:Q07866	Human	PMID:14970196
Molecular Function	GO:0019894	kinesin binding	Tor1a	IDA		Rat	PMID:14970196|RGD:1304300
Molecular Function	GO:0019894	kinesin binding	Tor1a	IPI	UniProtKB:P37285	Rat	PMID:14970196|RGD:1304300
Molecular Function	GO:0051787	misfolded protein binding	Tor1a	IPI	UniProtKB:O70258	Mouse	MGI:MGI:3712415|PMID:17200151
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:O14657	Human	PMID:15147511
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q01959	Human	PMID:15505207
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q8NFQ8	Human	PMID:15767459
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:O95295	Human	PMID:18167355
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q6ZMZ3	Human	PMID:18827015
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:O95295	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q8WXE9	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q9BT78	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q5JTV8	Human	PMID:23569223
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q8NFQ8	Human	PMID:23569223
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:P60409	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:P22692	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q6PCB6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q96FT7-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TOR1A	IPI	UniProtKB:Q9UNS2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tor1a	IPI	UniProtKB:Q4FZC9	Mouse	MGI:MGI:3814961|PMID:18827015
Molecular Function	GO:0005515	protein binding	Tor1a	IPI	PR:Q921T2	Mouse	PMID:20457914
Molecular Function	GO:0005515	protein binding	Tor1a	IPI	PR:Q69ZK5	Mouse	PMID:19535332
Molecular Function	GO:0005515	protein binding	Tor1a	IPI	PR:Q921T2	Mouse	PMID:15767459
Molecular Function	GO:0005515	protein binding	Tor1a	IPI	MGI:MGI:3582695	Mouse	PMID:15767459
Molecular Function	GO:0005515	protein binding	Tor1a	IPI	UniProtKB:D4AB66	Rat	PMID:21102408|RGD:8554353
Cellular Component	GO:0005737	cytoplasm	Tor1a	IDA		Mouse	PMID:11730696
Cellular Component	GO:0005737	cytoplasm	Tor1a	IDA		Rat	PMID:12671990|RGD:634735
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Tor1a	IDA		Rat	PMID:14970196|RGD:1304300
Cellular Component	GO:0005829	cytosol	tor1	IDA		Zfish	PMID:23028827
Cellular Component	GO:0005783	endoplasmic reticulum	TOR1A	IDA		Human	PMID:12671990
Cellular Component	GO:0005783	endoplasmic reticulum	Tor1a	IDA		Mouse	PMID:15767459
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TOR1A	IDA		Human	PMID:17037984
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TOR1A	IDA		Human	PMID:20015956
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Tor1a	IDA		Mouse	PMID:20015956
Cellular Component	GO:0070062	extracellular exosome	TOR1A	HDA		Human	PMID:19199708
Cellular Component	GO:0042406	extrinsic component of endoplasmic reticulum membrane	TOR1A	IDA		Human	PMID:17037984
Cellular Component	GO:0030426	growth cone	Tor1a	IDA		Rat	PMID:14970196|RGD:1304300
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TOR1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Tor1a	IDA		Rat	PMID:12671990|RGD:634735
Cellular Component	GO:0016020	membrane	TOR1A	IDA		Human	PMID:23569223
Cellular Component	GO:0043005	neuron projection	Tor1a	IDA		Rat	PMID:12671990|RGD:634735
Cellular Component	GO:0005635	nuclear envelope	Tor1a	IDA		Mouse	PMID:20457914
Cellular Component	GO:0005635	nuclear envelope	tor1	IDA		Zfish	PMID:23028827
Cellular Component	GO:0031965	nuclear membrane	TOR1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Tor1a	IDA		Mouse	PMID:11730696
Cellular Component	GO:0030141	secretory granule	Tor1a	IDA		Rat	PMID:18167355|RGD:8554821
Cellular Component	GO:0008021	synaptic vesicle	TOR1A	IDA		Human	PMID:21102408
Cellular Component	GO:0008021	synaptic vesicle	Tor1a	IDA		Rat	PMID:21102408|RGD:8554353
Biological Process	GO:0007155	cell adhesion	TOR1A	IMP		Human	PMID:16361107
Biological Process	GO:0061077	chaperone-mediated protein folding	TOR1A	IDA		Human	PMID:20169475
Biological Process	GO:0071712	ER-associated misfolded protein catabolic process	Tor1a	IDA		Mouse	MGI:MGI:3712415|PMID:17200151
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	TOR1A	IMP		Human	PMID:16361107
Biological Process	GO:0031175	neuron projection development	TOR1A	IMP		Human	PMID:16361107
Biological Process	GO:0031175	neuron projection development	TOR1A	IMP		Human	PMID:24930953
Biological Process	GO:0006998	nuclear envelope organization	Tor1a	IMP	MGI:MGI:3623421	Mouse	PMID:16364897
Biological Process	GO:0006998	nuclear envelope organization	Tor1a	IMP	MGI:MGI:3623422	Mouse	PMID:16364897
Biological Process	GO:0071763	nuclear membrane organization	Tor1a	IMP	MGI:MGI:3623422	Mouse	PMID:20080676
Biological Process	GO:0071763	nuclear membrane organization	Tor1a	IGI	MGI:MGI:1353605	Mouse	PMID:20457914
Biological Process	GO:0071763	nuclear membrane organization	Tor1a	IMP	MGI:MGI:3623421	Mouse	PMID:20457914
Biological Process	GO:0071763	nuclear membrane organization	Tor1a	IGI	MGI:MGI:3582693	Mouse	PMID:20457914
Biological Process	GO:0071763	nuclear membrane organization	Tor1a	IMP	MGI:MGI:3623421	Mouse	PMID:20080676
Biological Process	GO:0006996	organelle organization	Tor1a	IMP		Mouse	MGI:MGI:3814961|PMID:18827015
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	TOR1A	IMP		Human	PMID:21102408
Biological Process	GO:0000338	protein deneddylation	TOR1A	IMP		Human	PMID:21102408
Biological Process	GO:0034504	protein localization to nucleus	TOR1A	IMP	UniProtKB:Q6ZMZ3	Human	PMID:18827015
Biological Process	GO:0034504	protein localization to nucleus	Tor1a	IMP	UniProtKB:Q4FZC9	Mouse	MGI:MGI:3814961|PMID:18827015
Biological Process	GO:0051584	regulation of dopamine uptake involved in synaptic transmission	TOR1A	IDA		Human	PMID:15505207
Biological Process	GO:2000008	regulation of protein localization to cell surface	TOR1A	IMP		Human	PMID:15505207
Biological Process	GO:0006979	response to oxidative stress	Tor1a	IDA		Rat	PMID:12671990|RGD:634735
Biological Process	GO:0048499	synaptic vesicle membrane organization	TOR1A	IMP		Human	PMID:24930953
Biological Process	GO:0048489	synaptic vesicle transport	TOR1A	IMP		Human	PMID:18167355
Biological Process	GO:0044319	wound healing, spreading of cells	Tor1a	IMP		Mouse	MGI:MGI:3814961|PMID:18827015

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern