Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOX
  • Mouse genes Tox
  • Rat genes Tox
  • Zfish genes tox
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tox

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	Tox	IDA		Mouse	MGI:MGI:5632052|PMID:25527292
Molecular Function	GO:0005515	protein binding	TOX	IPI	UniProtKB:P59990	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOX	IPI	UniProtKB:Q13588	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOX	IPI	UniProtKB:Q6PEX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOX	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOX	IPI	UniProtKB:Q96MA1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOX	IPI	UniProtKB:Q92876	Human	PMID:32814053
Cellular Component	GO:0005634	nucleus	Tox	IDA		Mouse	MGI:MGI:2159528|PMID:11850626
Biological Process	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	Tox	IMP		Mouse	MGI:MGI:3773459|PMID:18195075
Biological Process	GO:0002362	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment	Tox	IMP		Mouse	MGI:MGI:3773459|PMID:18195075
Biological Process	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	Tox	IMP		Mouse	MGI:MGI:2159528|PMID:11850626
Biological Process	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	Tox	IMP		Mouse	MGI:MGI:3045816|PMID:15078895
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Tox	IMP		Mouse	MGI:MGI:5632052|PMID:25527292
Biological Process	GO:0048535	lymph node development	Tox	IMP	MGI:MGI:3773716	Mouse	PMID:20818394
Biological Process	GO:0030098	lymphocyte differentiation	Tox	IMP	MGI:MGI:3773716	Mouse	PMID:20818394
Biological Process	GO:0001779	natural killer cell differentiation	TOX	IMP		Human	PMID:21126536
Biological Process	GO:0002364	NK T cell lineage commitment	Tox	IMP		Mouse	MGI:MGI:3773459|PMID:18195075
Biological Process	GO:0048541	Peyer's patch development	Tox	IMP	MGI:MGI:3773716	Mouse	PMID:20818394
Biological Process	GO:1901537	positive regulation of DNA demethylation	Tox	IMP		Mouse	MGI:MGI:3045816|PMID:15078895
Biological Process	GO:0032825	positive regulation of natural killer cell differentiation	Tox	IMP	MGI:MGI:3773716	Mouse	PMID:20818394
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	Tox	IMP		Mouse	MGI:MGI:5632052|PMID:25527292
Biological Process	GO:0010976	positive regulation of neuron projection development	Tox	IMP		Mouse	MGI:MGI:5632052|PMID:25527292
Biological Process	GO:1902232	regulation of positive thymic T cell selection	Tox	IMP		Mouse	MGI:MGI:3773459|PMID:18195075

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern