Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPI1
  • Mouse genes Tpi1
  • Rat genes LOC500959,Tpi1
  • Zfish genes tpi1a,tpi1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpi1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016853	isomerase activity	Tpi1	IDA		Mouse	PMID:566475
Molecular Function	GO:0005515	protein binding	TPI1	IPI	UniProtKB:P12004	Human	PMID:20849852
Molecular Function	GO:0005515	protein binding	TPI1	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TPI1	IPI	UniProtKB:P21754	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	TPI1	IPI	UniProtKB:Q12836	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	TPI1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tpi1	IPI	UniProtKB:Q9CPW0	Mouse	PMID:25707359
Molecular Function	GO:0005515	protein binding	Tpi1	IPI	RGD:69099	Rat	PMID:16170200|RGD:1599585
Molecular Function	GO:0042803	protein homodimerization activity	TPI1	IDA		Human	PMID:18562316
Molecular Function	GO:0004807	triose-phosphate isomerase activity	TPI1	IDA		Human	PMID:18562316
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:3443296
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:176725
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:19289113
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:2693209
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:566476
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:15155459
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	MGI:MGI:62142
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:17023274
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IMP	MGI:MGI:2183489	Mouse	PMID:3796661
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:204065
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Mouse	PMID:8417789
Molecular Function	GO:0004807	triose-phosphate isomerase activity	Tpi1	IDA		Rat	PMID:1834654|RGD:1599371
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TPI1	IPI	UniProtKB:O60260	Human	PMID:19725078
Cellular Component	GO:0005829	cytosol	Tpi1	IDA		Mouse	PMID:12581871
Cellular Component	GO:0005829	cytosol	Tpi1	IDA		Rat	PMID:1834654|RGD:1599371
Cellular Component	GO:0070062	extracellular exosome	TPI1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TPI1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	TPI1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	TPI1	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	TPI1	HDA		Human	PMID:23580065
Cellular Component	GO:0005634	nucleus	TPI1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Tpi1	IDA		Rat	PMID:15942958|RGD:1598733
Biological Process	GO:0061621	canonical glycolysis	Tpi1	IGI	MGI:MGI:3780541	Mouse	PMID:30174313
Biological Process	GO:0005975	carbohydrate metabolic process	Tpi1	IDA		Rat	PMID:1834654|RGD:1599371
Biological Process	GO:0009790	embryo development	Tpi1	IMP	MGI:MGI:2183490	Mouse	PMID:2693209
Biological Process	GO:0009790	embryo development	Tpi1	IMP	MGI:MGI:2183489	Mouse	PMID:2693209
Biological Process	GO:0006094	gluconeogenesis	Tpi1	IDA		Mouse	PMID:31891762
Biological Process	GO:0006006	glucose metabolic process	Tpi1	IDA		Mouse	PMID:2693209
Biological Process	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process	TPI1	IDA		Human	PMID:18562316
Biological Process	GO:0019682	glyceraldehyde-3-phosphate metabolic process	Tpi1	IDA		Mouse	MGI:MGI:3054313|PMID:15155459
Biological Process	GO:0007275	multicellular organism development	Tpi1	IMP		Mouse	PMID:3796661

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern