Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPK1
  • Mouse genes Tpk1
  • Rat genes Tpk1
  • Zfish genes tpk1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TPK1	IPI	UniProtKB:Q9H3S4	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	TPK1	IPI	UniProtKB:Q9H3S4	Human	PMID:29892012
Molecular Function	GO:0042802	identical protein binding	TPK1	IPI	UniProtKB:Q9H3S4	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	TPK1	IPI	UniProtKB:Q9H3S4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TPK1	IPI	UniProtKB:O14841	Human	PMID:32296183
Molecular Function	GO:0004788	thiamine diphosphokinase activity	TPK1	IDA		Human	PMID:11342111
Molecular Function	GO:0004788	thiamine diphosphokinase activity	Tpk1	IDA		Mouse	PMID:10567383
Biological Process	GO:0009229	thiamine diphosphate biosynthetic process	TPK1	IDA		Human	PMID:11342111
Biological Process	GO:0006772	thiamine metabolic process	Tpk1	IDA		Mouse	PMID:10567383

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern