Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPPP
  • Mouse genes Tppp
  • Rat genes Tppp
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tppp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003924	GTPase activity	TPPP	IDA		Human	PMID:21316364
Molecular Function	GO:0000287	magnesium ion binding	TPPP	IDA		Human	PMID:21316364
Molecular Function	GO:0140490	microtubule nucleator activity	TPPP	IDA		Human	PMID:31522887
Molecular Function	GO:0140677	molecular function activator activity	TPPP	IDA		Human	PMID:22484033
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:P37840	Human	PMID:15590652
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:P37840	Human	PMID:17027006
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:P53667	Human	PMID:18028908
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:Q9UBN7	Human	PMID:20308065
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:P53671	Human	PMID:22328514
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:Q13464	Human	PMID:23093407
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:P37840	Human	PMID:27671864
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:Q02539	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:Q02539	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:Q8NC26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:P45880	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TPPP	IPI	UniProtKB:Q8N7X4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tppp	IPI	UniProtKB:P37377	Rat	PMID:15590652|RGD:8554005
Molecular Function	GO:0046983	protein dimerization activity	TPPP	IDA		Human	PMID:22484033
Molecular Function	GO:0042803	protein homodimerization activity	TPPP	IDA		Human	PMID:26289831
Molecular Function	GO:0015631	tubulin binding	TPPP	IDA		Human	PMID:17105200
Cellular Component	GO:0005737	cytoplasm	TPPP	IDA		Human	PMID:18028908
Cellular Component	GO:0005737	cytoplasm	Tppp	IDA		Mouse	MGI:MGI:4361981|PMID:18028908
Cellular Component	GO:0005829	cytosol	TPPP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	TPPP	IDA		Human	PMID:31522887
Cellular Component	GO:0005874	microtubule	TPPP	IDA		Human	PMID:18028908
Cellular Component	GO:0005874	microtubule	Tppp	IDA		Mouse	MGI:MGI:4361981|PMID:18028908
Cellular Component	GO:0097427	microtubule bundle	TPPP	IDA		Human	PMID:17105200
Cellular Component	GO:0005739	mitochondrion	TPPP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	TPPP	IDA		Human	PMID:22328514
Cellular Component	GO:0043209	myelin sheath	Tppp	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005634	nucleus	TPPP	IDA		Human	PMID:18028908
Cellular Component	GO:0005634	nucleus	Tppp	IDA		Mouse	MGI:MGI:4361981|PMID:18028908
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TPPP	IDA		Human	PMID:15590652
Cellular Component	GO:0150051	postsynaptic Golgi apparatus	Tppp	IDA		Rat	PMID:31522887|RGD:14995310
Biological Process	GO:0030953	astral microtubule organization	TPPP	IDA		Human	PMID:22328514
Biological Process	GO:0001578	microtubule bundle formation	TPPP	IDA		Human	PMID:17105200
Biological Process	GO:0001578	microtubule bundle formation	TPPP	IDA		Human	PMID:26289831
Biological Process	GO:0051418	microtubule nucleation by microtubule organizing center	TPPP	IDA		Human	PMID:31522887
Biological Process	GO:0046785	microtubule polymerization	TPPP	IDA		Human	PMID:18028908
Biological Process	GO:0046785	microtubule polymerization	Tppp	IDA		Mouse	MGI:MGI:4361981|PMID:18028908
Biological Process	GO:0032288	myelin assembly	Tppp	IMP		Mouse	MGI:MGI:6368053|PMID:31522887
Biological Process	GO:0032288	myelin assembly	Tppp	IMP		Rat	PMID:19606501|RGD:14995315
Biological Process	GO:1904428	negative regulation of tubulin deacetylation	TPPP	IDA		Human	PMID:20308065
Biological Process	GO:1904428	negative regulation of tubulin deacetylation	TPPP	IDA		Human	PMID:23093407
Biological Process	GO:0014003	oligodendrocyte development	Tppp	IMP		Mouse	MGI:MGI:6368053|PMID:31522887
Biological Process	GO:0048709	oligodendrocyte differentiation	Tppp	IMP		Mouse	MGI:MGI:6368053|PMID:31522887
Biological Process	GO:0031643	positive regulation of myelination	Tppp	IMP		Mouse	MGI:MGI:6368053|PMID:31522887
Biological Process	GO:0031643	positive regulation of myelination	Tppp	IMP		Rat	PMID:19606501|RGD:14995315
Biological Process	GO:0032273	positive regulation of protein polymerization	TPPP	IDA		Human	PMID:15590652
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	TPPP	IDA		Human	PMID:23093407

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern