Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPRKB
  • Mouse genes Tprkb
  • Rat genes Tprkb
  • Zfish genes tprkb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tprkb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q14657,UniProtKB:Q96S44,UniProtKB:Q9BXV9,UniProtKB:Q9NPF4	Human	PMID:27903914
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:28805828
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:32707033
Molecular Function	GO:0019901	protein kinase binding	TPRKB	IPI	UniProtKB:Q96S44	Human	PMID:12659830
Cellular Component	GO:0005737	cytoplasm	TPRKB	IDA		Human	PMID:28805828
Cellular Component	GO:0005829	cytosol	TPRKB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	TPRKB	IDA		Human	PMID:12659830
Cellular Component	GO:0000408	EKC/KEOPS complex	TPRKB	IDA		Human	PMID:27903914
Cellular Component	GO:0000408	EKC/KEOPS complex	TPRKB	IDA		Human	PMID:28805828
Cellular Component	GO:0005634	nucleus	TPRKB	IDA		Human	PMID:12659830
Cellular Component	GO:0005634	nucleus	TPRKB	IDA		Human	PMID:28805828
Biological Process	GO:0002949	tRNA threonylcarbamoyladenosine modification	TPRKB	IDA		Human	PMID:28805828

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern