Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPST2
  • Mouse genes Tpst2
  • Rat genes Tpst2
  • Zfish genes tpst2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpst2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042803	protein homodimerization activity	TPST2	IPI	UniProtKB:O60704	Human	PMID:23481380
Molecular Function	GO:0008476	protein-tyrosine sulfotransferase activity	TPST2	IDA		Human	PMID:23481380
Molecular Function	GO:0008476	protein-tyrosine sulfotransferase activity	TPST2	IDA		Human	PMID:9733778
Molecular Function	GO:0008476	protein-tyrosine sulfotransferase activity	Tpst2	IMP	MGI:MGI:3512111	Mouse	PMID:17046811
Cellular Component	GO:0005783	endoplasmic reticulum	TPST2	IDA		Human	GO_REF:0000054
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	Tpst2	IMP	MGI:MGI:3512111	Mouse	PMID:21339297
Biological Process	GO:0006478	peptidyl-tyrosine sulfation	TPST2	IDA		Human	PMID:23481380
Biological Process	GO:0006478	peptidyl-tyrosine sulfation	TPST2	IDA		Human	PMID:9733778
Biological Process	GO:0006478	peptidyl-tyrosine sulfation	Tpst2	IMP	MGI:MGI:3512111	Mouse	PMID:17046811
Biological Process	GO:0060468	prevention of polyspermy	Tpst2	IMP	MGI:MGI:3512111	Mouse	PMID:21339297

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern