Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRAF3
  • Mouse genes Traf3
  • Rat genes Traf3
  • Zfish genes traf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Traf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TRAF3	IPI	UniProtKB:Q13114	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q8TDR0	Human	PMID:10791955
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q92844	Human	PMID:12005438
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9HAV5	Human	PMID:12270937
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q92844	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9HAV5	Human	PMID:15280356
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P12931	Human	PMID:19419966
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q7Z434	Human	PMID:19893624
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9NWF9	Human	PMID:19893624
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P61964	Human	PMID:20080758
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q15326	Human	PMID:20138174
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q96CV9	Human	PMID:20174559
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P36941	Human	PMID:20732415
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:A2APF7	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P15314	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q92844	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9QYP6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P15056	Human	PMID:23153539
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O43353	Human	PMID:23333941
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9Y2R2	Human	PMID:23871208
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O00463	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9UHD2	Human	PMID:27135603
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P04406	Human	PMID:27387501
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O00571	Human	PMID:27980081
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q14164|UniProtKB:Q14653	Human	PMID:27980081
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q7Z434	Human	PMID:27980081
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O95721	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P36941	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q99558	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9HAV5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q92844	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q99558	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q99558	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O00463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O95721	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P28062-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P54725	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q0D2K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q13546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q17RL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q52MB2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q5T681	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q6ZSB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q86UB2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q8IYE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q8N9N2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q8NAM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q96HA1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q96PC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q99558	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9UKD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9Y547	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9Y692	Human	PMID:32514408
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:O43353	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q99558	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9UHD2	Human	PMID:33372174
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q92844	Human	PMID:34084167
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:Q9UHD2	Human	PMID:34084167
Molecular Function	GO:0005515	protein binding	TRAF3	IPI	UniProtKB:P25942	Human	PMID:7527023
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:Q80UF7|UniProtKB:Q9UHD2	Mouse	MGI:MGI:5918298|PMID:16306936
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:Q9Y2R2	Mouse	MGI:MGI:5562517|PMID:23871208
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:P22366|UniProtKB:Q80UF7	Mouse	MGI:MGI:4839450|PMID:16306937
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:P39429	Mouse	MGI:MGI:5009780|PMID:20818435
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:Q8VCF0	Mouse	MGI:MGI:5508627|PMID:16858409
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:O35305	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:Q9UHD2	Mouse	MGI:MGI:6467691|PMID:27094905
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:P22366	Mouse	MGI:MGI:5305352|PMID:22011580
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:B2RUR8	Mouse	MGI:MGI:5474156|PMID:23334419
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:Q3UDK1	Mouse	MGI:MGI:3831253|PMID:18849341
Molecular Function	GO:0005515	protein binding	Traf3	IPI	UniProtKB:P48453|UniProtKB:P63328	Mouse	MGI:MGI:6216148|PMID:26029823
Molecular Function	GO:0005515	protein binding	Traf3	IPI	PR:E9Q5R7	Mouse	PMID:22503542
Molecular Function	GO:0019901	protein kinase binding	Traf3	IPI	UniProtKB:Q99558	Mouse	MGI:MGI:4835145|PMID:17158868
Molecular Function	GO:0019903	protein phosphatase binding	TRAF3	IPI	UniProtKB:Q9Y2R2	Human	PMID:23871208
Molecular Function	GO:0031996	thioesterase binding	TRAF3	IPI	UniProtKB:Q93009	Human	PMID:11279055
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	TRAF3	IPI	UniProtKB:Q9NP84	Human	PMID:11728344
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF3	IDA		Human	PMID:19898473
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TRAF3	IPI	UniProtKB:O94972	Human	PMID:11279055
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRAF3	IDA		Human	PMID:19898473
Cellular Component	GO:0035631	CD40 receptor complex	Traf3	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Traf3	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0005768	endosome	TRAF3	IDA		Human	PMID:18222170
Cellular Component	GO:0005739	mitochondrion	TRAF3	IDA		Human	PMID:19898473
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	TRAF3	IMP		Human	PMID:20185819
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Traf3	IMP		Mouse	MGI:MGI:3722053|PMID:17015635
Biological Process	GO:0032481	positive regulation of type I interferon production	TRAF3	IDA		Human	PMID:19898473
Biological Process	GO:0001817	regulation of cytokine production	Traf3	IMP		Mouse	MGI:MGI:4839450|PMID:16306937
Biological Process	GO:0050688	regulation of defense response to virus	Traf3	IMP		Mouse	MGI:MGI:4839450|PMID:16306937
Biological Process	GO:0032648	regulation of interferon-beta production	Traf3	IMP		Mouse	MGI:MGI:4839450|PMID:16306937
Biological Process	GO:0030162	regulation of proteolysis	TRAF3	IMP		Human	PMID:20185819
Biological Process	GO:0030162	regulation of proteolysis	Traf3	IDA		Mouse	MGI:MGI:4835145|PMID:17158868
Biological Process	GO:0030162	regulation of proteolysis	Traf3	IMP		Mouse	MGI:MGI:3722053|PMID:17015635
Biological Process	GO:0001878	response to yeast	traf3	IDA		Zfish	PMID:23947337
Biological Process	GO:0002224	toll-like receptor signaling pathway	Traf3	IMP		Mouse	MGI:MGI:4839450|PMID:16306937
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	TRAF3	IMP		Human	PMID:20185819
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	Traf3	IMP		Mouse	MGI:MGI:3722053|PMID:17015635

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern