Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRAF4
  • Mouse genes Traf4
  • Rat genes Traf4
  • Zfish genes traf4a,traf4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Traf4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TRAF4	IPI	UniProtKB:Q9BUZ4	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	TRAF4	IPI	UniProtKB:Q9BUZ4	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	TRAF4	IPI	UniProtKB:Q9BUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P07174	Human	PMID:10514511
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9Y6R4	Human	PMID:16157600
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O43294	Human	PMID:16330715
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P14598	Human	PMID:16330715
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9HCE7-2	Human	PMID:19937093
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O00308	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13895	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q7L5A3	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9E7P0	Human	PMID:22014111
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N9I9	Human	PMID:22493164
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O60341	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A8KA13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:E9PJI5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O00308	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O75052	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P11441	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P17036	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P29597	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P47897	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P47897-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P63165	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13084	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13625-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13895	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q7Z3B3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q86U76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8IX06	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8IX15-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N7F7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8TBE0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q96BU6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q96D16	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q96EA4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9H0M0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9H8Y8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NPH2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NXW9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P0N9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P0T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9Y2W2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NPH2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A0A0S2Z4Q4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A0A0S2Z5G4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A0A0S2Z5X4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:B4DE54	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O14964	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N9N5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N9N5-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q08379	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P0N9	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P17980	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q7L5A3	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9H8Y8	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13084	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N7F7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NXW9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P0N9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A0A0U1RQF7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A2BDE7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O00167-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O00308	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O43559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O60341	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P09067	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P11441	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P14598	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P14678-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P17036	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P17980	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P47897	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P50570	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P52435	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q01664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q05516	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13360-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q13895	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q15427	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q15599	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q6IQ23-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q6P2H3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q7L5A3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q86X51	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N7F7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N9I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8NCA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8TBE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q92824-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q96PV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9BQQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9BRJ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9BUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9C0D7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9H1A7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9HCK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NP66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NSD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9NYA3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P0N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P0T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9P2A4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9UBP5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9UJ78-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9UPG8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9Y2P0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q9Y4B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O14656-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:O14773	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P22314	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF4	IPI	UniProtKB:Q8N187	Human	PMID:32814053
Molecular Function	GO:0019901	protein kinase binding	Traf4	IPI	UniProtKB:O08648	Mouse	MGI:MGI:4821077|PMID:16157600
Molecular Function	GO:0031996	thioesterase binding	TRAF4	IPI	UniProtKB:Q93009	Human	PMID:11279055
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	TRAF4	IPI	UniProtKB:Q9NP84	Human	PMID:11728344
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TRAF4	IPI	UniProtKB:O94972	Human	PMID:11279055
Molecular Function	GO:0050699	WW domain binding	TRAF4	IPI	UniProtKB:Q9HCE7	Human	PMID:19937093
Cellular Component	GO:0005737	cytoplasm	TRAF4	IDA		Human	PMID:16157600
Cellular Component	GO:0005829	cytosol	TRAF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	TRAF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TRAF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TRAF4	IDA		Human	PMID:18087216
Biological Process	GO:0045198	establishment of epithelial cell apical/basal polarity	traf4a	IMP	ZFIN:ZDB-GENO-200624-2	Zfish	PMID:29961393
Biological Process	GO:0002072	optic cup morphogenesis involved in camera-type eye development	traf4a	IMP	ZFIN:ZDB-GENO-200624-2	Zfish	PMID:29961393
Biological Process	GO:0003405	optic vesicle elongation	traf4a	IMP	ZFIN:ZDB-GENO-200624-2	Zfish	PMID:29961393
Biological Process	GO:0046330	positive regulation of JNK cascade	TRAF4	IDA		Human	PMID:16157600
Biological Process	GO:0045860	positive regulation of protein kinase activity	TRAF4	IDA		Human	PMID:16157600
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Traf4	IMP	MGI:MGI:2158361	Mouse	PMID:10934170
Biological Process	GO:0030323	respiratory tube development	Traf4	IMP	MGI:MGI:2158361	Mouse	PMID:10934170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern