Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRAF6
  • Mouse genes Traf6
  • Rat genes Traf6
  • Zfish genes traf6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Traf6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042826	histone deacetylase binding	TRAF6	IPI	UniProtKB:Q13547	Human	PMID:18093978
Molecular Function	GO:0042802	identical protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:19465916
Molecular Function	GO:0042802	identical protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:22493164
Molecular Function	GO:0042802	identical protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43318	Human	PMID:10094049
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q15750	Human	PMID:10094049
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9QZH6	Human	PMID:10465784
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P07174	Human	PMID:10514511
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q86VP1	Human	PMID:10920205
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q66677	Human	PMID:11238466
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P37198	Human	PMID:11244088
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43791	Human	PMID:11279055
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O94972	Human	PMID:11279055
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q93009	Human	PMID:11279055
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P51617	Human	PMID:11397809
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P21580	Human	PMID:11463333
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q6GQQ9	Human	PMID:11463333
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UGI0	Human	PMID:11463333
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P51617	Human	PMID:11518704
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9NYJ8	Human	PMID:11518704
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9NP84	Human	PMID:11728344
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8TD23	Human	PMID:11751921
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P25942	Human	PMID:12140561
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P51617	Human	PMID:12242293
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9HAV5	Human	PMID:12270937
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43734	Human	PMID:12459498
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43318	Human	PMID:12496252
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q6IA17	Human	PMID:12925853
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8IUC6	Human	PMID:14530355
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8IUC6	Human	PMID:14982987
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P19525	Human	PMID:15121867
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UDY8	Human	PMID:15125833
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9HAV5	Human	PMID:15280356
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q01220	Human	PMID:15998638
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q12933	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P14778	Human	PMID:16286467
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P32121	Human	PMID:16378096
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P49407	Human	PMID:16378096
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9Y4K3	Human	PMID:16378096
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13501	Human	PMID:16874300
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8V2D1	Human	PMID:16932746
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9NYA1	Human	PMID:17124500
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13501	Human	PMID:17389358
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9BYM8	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P0CG48	Human	PMID:17703191
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q86VP1	Human	PMID:17703191
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UDY8	Human	PMID:17948050
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P10242	Human	PMID:18093978
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P46060	Human	PMID:18093978
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P0CG48	Human	PMID:18239685
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q86VP1	Human	PMID:18239685
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P10221	Human	PMID:18682563
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P36897	Human	PMID:18758450
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9BVN2-2	Human	PMID:19365808
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P61088	Human	PMID:19465916
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P51668	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P61077	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P61088	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P62837	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9NYJ8	Human	PMID:19675569
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P31749	Human	PMID:19713527
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P31751	Human	PMID:19713527
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43318	Human	PMID:19820695
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P0CG48	Human	PMID:19820695
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9Y6R0	Human	PMID:20079715
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P61964	Human	PMID:20080758
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O94826	Human	PMID:20628368
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P25942	Human	PMID:20676093
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O00463	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43734	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q12933	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13077	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P07174	Human	PMID:21541365
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q12933	Human	PMID:21782231
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O14879	Human	PMID:21813773
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43187	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q7Z434	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43187	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13077	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q86VP1	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9NYJ8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O00463	Human	PMID:22493164
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UDY8	Human	PMID:22528498
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UKE5	Human	PMID:22904686
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q7Z434	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O75385	Human	PMID:23524951
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9C0C7	Human	PMID:23524951
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9C0C7-3	Human	PMID:23524951
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O00463	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43734	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O75604	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P07947	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8N1B4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8WWZ3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UNA4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8IUC6	Human	PMID:25736436
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q14694	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q5D1E8	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q92844	Human	PMID:25861989
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q96CG3	Human	PMID:26068852
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q7Z434	Human	PMID:26385923
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O00463	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13077	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q96CG3	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P61088	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O43187	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13077	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9HAV5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O00463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:O94888	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P07947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P24278	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P54725	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P62837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q5VVQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8IWQ3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8N3F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8NA54	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q96DC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9HAC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:Q9Y616	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P04271	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P09936	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF6	IPI	UniProtKB:P43405-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q3UDK1	Mouse	MGI:MGI:3773782|PMID:16221674
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q9EQY0	Mouse	MGI:MGI:5516130|PMID:23942232
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q9QXD8	Mouse	MGI:MGI:3698661|PMID:17092936
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q62227	Mouse	MGI:MGI:5086034|PMID:21725320
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:P22366	Mouse	MGI:MGI:4839450|PMID:16306937
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:P35235	Mouse	MGI:MGI:5432331|PMID:22522491
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q62406-1|UniProtKB:Q8K4B2|UniProtKB:Q8N7N6|UniProtKB:Q9QZH6	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q793I8	Mouse	MGI:MGI:3687915|PMID:12566447
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q8C0E5	Mouse	MGI:MGI:3687919|PMID:12459498
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q9QZH6	Mouse	MGI:MGI:5006867|PMID:21525932
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q8K4B2	Mouse	MGI:MGI:5553230|PMID:23376919
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q96CG3	Mouse	MGI:MGI:6695670|PMID:15047173
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q8CBB9	Mouse	MGI:MGI:4943343|PMID:21435586
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:O35305	Mouse	MGI:MGI:1334074|PMID:10097072
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:P27512	Mouse	MGI:MGI:84147|PMID:8910514
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q8N7N6	Mouse	MGI:MGI:5291883|PMID:21822257
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:P22366	Mouse	MGI:MGI:5305352|PMID:22011580
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q61084	Mouse	MGI:MGI:3028350|PMID:14661019
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q3UKC1	Mouse	MGI:MGI:3774717|PMID:18239685
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q9QZH6	Mouse	MGI:MGI:1344119|PMID:10465784
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:P17879	Mouse	MGI:MGI:3629375|PMID:16697380
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q3UDK1	Mouse	MGI:MGI:3831253|PMID:18849341
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q61084	Mouse	MGI:MGI:5508260|PMID:16362041
Molecular Function	GO:0005515	protein binding	Traf6	IPI	UniProtKB:Q60943	Mouse	PMID:19825828
Molecular Function	GO:0005515	protein binding	Traf6	IPI	PR:Q5DU56	Mouse	PMID:22863753
Molecular Function	GO:0005515	protein binding	Traf6	IPI	PR:Q8BXR6	Mouse	PMID:23042151
Molecular Function	GO:0043422	protein kinase B binding	TRAF6	IPI	UniProtKB:Q9Y243	Human	PMID:19713527
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	TRAF6	IDA		Human	PMID:23776175
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF6	IDA		Human	PMID:15125833
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF6	IDA		Human	PMID:17135271
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF6	IDA		Human	PMID:19713527
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF6	IDA		Human	PMID:23514740
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRAF6	IDA		Human	PMID:26839314
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Traf6	IDA		Mouse	PMID:16252010
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Traf6	IMP		Mouse	PMID:23042151
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRAF6	EXP		Human	PMID:15361868
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRAF6	EXP		Human	PMID:17135271
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRAF6	EXP		Human	PMID:17728323
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRAF6	EXP		Human	PMID:26620909
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Traf6	IDA		Mouse	MGI:MGI:3610521|PMID:16252010
Molecular Function	GO:0034450	ubiquitin-ubiquitin ligase activity	TRAF6	IDA		Human	PMID:15465037
Molecular Function	GO:0034450	ubiquitin-ubiquitin ligase activity	TRAF6	IDA		Human	PMID:18758450
Cellular Component	GO:0035631	CD40 receptor complex	Traf6	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0005737	cytoplasm	TRAF6	IDA		Human	PMID:22851693
Cellular Component	GO:0005737	cytoplasm	TRAF6	IDA		Human	PMID:16378096
Cellular Component	GO:0005737	cytoplasm	TRAF6	IDA		Human	PMID:18093978
Cellular Component	GO:0005737	cytoplasm	Traf6	IDA		Rat	PMID:27538408|RGD:151347179
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Traf6	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0005829	cytosol	Traf6	IDA		Mouse	MGI:MGI:3694380|PMID:16831874
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	TRAF6	IDA		Human	PMID:23514740
Cellular Component	GO:0005811	lipid droplet	Traf6	IDA		Mouse	MGI:MGI:4943343|PMID:21435586
Cellular Component	GO:0005634	nucleus	TRAF6	IDA		Human	PMID:18093978
Cellular Component	GO:0048471	perinuclear region of cytoplasm	TRAF6	IDA		Human	PMID:11751921
Cellular Component	GO:0005886	plasma membrane	TRAF6	IDA		Human	PMID:18093978
Cellular Component	GO:0032991	protein-containing complex	TRAF6	IDA		Human	PMID:23776175
Cellular Component	GO:0032991	protein-containing complex	Traf6	IDA		Rat	PMID:20967881|RGD:5130945
Biological Process	GO:0007250	activation of NF-kappaB-inducing kinase activity	TRAF6	IMP		Human	PMID:15125833
Biological Process	GO:0032147	activation of protein kinase activity	TRAF6	IDA		Human	PMID:17135271
Biological Process	GO:0009887	animal organ morphogenesis	Traf6	IMP	MGI:MGI:2675469	Mouse	PMID:15705807
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Traf6	IMP	MGI:MGI:2678775	Mouse	PMID:14499111
Biological Process	GO:0046849	bone remodeling	Traf6	IMP		Mouse	MGI:MGI:2181820|PMID:10421844
Biological Process	GO:0045453	bone resorption	Traf6	IMP		Mouse	MGI:MGI:1335941|PMID:10215628
Biological Process	GO:0048468	cell development	Traf6	IMP	MGI:MGI:2675469	Mouse	PMID:15705807
Biological Process	GO:1904385	cellular response to angiotensin	Traf6	IEP		Rat	PMID:27249171|RGD:155646134
Biological Process	GO:0071345	cellular response to cytokine stimulus	TRAF6	IMP		Human	PMID:25515214
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Traf6	IEP		Rat	PMID:27249171|RGD:155646134
Biological Process	GO:0071222	cellular response to lipopolysaccharide	TRAF6	IDA		Human	PMID:23776175
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Traf6	IMP		Rat	PMID:15890643|RGD:1579817
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	TRAF6	IDA		Human	PMID:26839314
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Traf6	IMP		Mouse	MGI:MGI:4442152|PMID:17633018
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Traf6	IGI	MGI:MGI:2444070	Mouse	PMID:22863753
Biological Process	GO:0006955	immune response	Traf6	IMP	MGI:MGI:2675469	Mouse	PMID:15705807
Biological Process	GO:0001701	in utero embryonic development	Traf6	IMP	MGI:MGI:4840586	Mouse	PMID:27996060
Biological Process	GO:0045087	innate immune response	traf6	IMP	ZFIN:ZDB-MRPHLNO-101208-2	Zfish	PMID:20851470
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	Traf6	IMP		Mouse	MGI:MGI:2181820|PMID:10421844
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	Traf6	IMP		Rat	PMID:20967881|RGD:5130945
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf6	IMP		Mouse	PMID:19825828
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf6	IDA		Mouse	PMID:19825828
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	TRAF6	IDA		Human	PMID:35183823
Biological Process	GO:0007254	JNK cascade	Traf6	IMP		Rat	PMID:15890643|RGD:1579817
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Traf6	IGI	MGI:MGI:2385852	Mouse	PMID:26458771
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Traf6	IMP		Mouse	PMID:26458771
Biological Process	GO:0043011	myeloid dendritic cell differentiation	Traf6	IMP	MGI:MGI:2678775	Mouse	PMID:14499111
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TRAF6	IMP		Human	PMID:18093978
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TRAF6	IMP		Human	PMID:18093978
Biological Process	GO:0001843	neural tube closure	Traf6	IMP		Mouse	MGI:MGI:2181331|PMID:11007897
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Traf6	IMP	MGI:MGI:2675469	Mouse	PMID:14699584
Biological Process	GO:0001503	ossification	Traf6	IMP	MGI:MGI:1859953	Mouse	PMID:10215628
Biological Process	GO:0030316	osteoclast differentiation	Traf6	IMP		Mouse	MGI:MGI:2181820|PMID:10421844
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	TRAF6	IMP		Human	PMID:12296995
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	traf6	IDA		Zfish	PMID:15829296
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TRAF6	IDA		Human	PMID:17135271
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Traf6	IMP		Mouse	MGI:MGI:5499721|PMID:20345905
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Traf6	IMP		Mouse	MGI:MGI:3054342|PMID:15322147
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Traf6	IGI	MGI:MGI:2444070	Mouse	PMID:22863753
Biological Process	GO:0032735	positive regulation of interleukin-12 production	Traf6	IMP	MGI:MGI:2678775	Mouse	PMID:14499111
Biological Process	GO:0032743	positive regulation of interleukin-2 production	TRAF6	IMP		Human	PMID:15125833
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Traf6	IMP	MGI:MGI:2678775	Mouse	PMID:14499111
Biological Process	GO:0043507	positive regulation of JUN kinase activity	TRAF6	IDA		Human	PMID:11751921
Biological Process	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	TRAF6	IMP		Human	PMID:25515214
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Traf6	IMP		Mouse	MGI:MGI:1335941|PMID:10215628
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRAF6	IDA		Human	PMID:11279055
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRAF6	IDA		Human	PMID:11751921
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRAF6	IMP		Human	PMID:12296995
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRAF6	IDA		Human	PMID:16378096
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Traf6	IMP		Mouse	MGI:MGI:5499721|PMID:20345905
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TRAF6	IMP		Human	PMID:25515214
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	TRAF6	IDA		Human	PMID:17135271
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Traf6	IMP		Rat	PMID:15890643|RGD:1579817
Biological Process	GO:0002726	positive regulation of T cell cytokine production	TRAF6	IMP		Human	PMID:15125833
Biological Process	GO:0042102	positive regulation of T cell proliferation	Traf6	IMP		Mouse	MGI:MGI:2181820|PMID:10421844
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TRAF6	IDA		Human	PMID:11751921
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	TRAF6	IDA		Human	PMID:11751921
Biological Process	GO:0051865	protein autoubiquitination	TRAF6	IDA		Human	PMID:23776175
Biological Process	GO:0051865	protein autoubiquitination	TRAF6	IDA		Human	PMID:17135271
Biological Process	GO:0051865	protein autoubiquitination	TRAF6	IDA		Human	PMID:18093978
Biological Process	GO:0070534	protein K63-linked ubiquitination	TRAF6	IGI	UniProtKB:P0CG47	Human	PMID:17135271
Biological Process	GO:0070534	protein K63-linked ubiquitination	TRAF6	IGI	UniProtKB:P0CG47	Human	PMID:19675569
Biological Process	GO:0070534	protein K63-linked ubiquitination	TRAF6	IDA		Human	PMID:19713527
Biological Process	GO:0070534	protein K63-linked ubiquitination	TRAF6	IDA		Human	PMID:21068390
Biological Process	GO:0070534	protein K63-linked ubiquitination	TRAF6	IDA		Human	PMID:23524951
Biological Process	GO:0070534	protein K63-linked ubiquitination	Traf6	IDA		Mouse	MGI:MGI:3610521|PMID:16252010
Biological Process	GO:0000209	protein polyubiquitination	TRAF6	IDA		Human	PMID:15125833
Biological Process	GO:0000209	protein polyubiquitination	TRAF6	IDA		Human	PMID:19675569
Biological Process	GO:0000209	protein polyubiquitination	Traf6	IMP		Mouse	PMID:19825828
Biological Process	GO:0016567	protein ubiquitination	Traf6	IGI	MGI:MGI:97072	Mouse	PMID:22095711
Biological Process	GO:0016567	protein ubiquitination	Traf6	IDA		Mouse	PMID:23042151
Biological Process	GO:0002637	regulation of immunoglobulin production	Traf6	IDA		Mouse	PMID:12958312
Biological Process	GO:0009617	response to bacterium	traf6	IDA		Zfish	PMID:15829296
Biological Process	GO:0070555	response to interleukin-1	TRAF6	IDA		Human	PMID:17135271
Biological Process	GO:0002931	response to ischemia	Traf6	IEP		Rat	PMID:27538408|RGD:151347179
Biological Process	GO:0009615	response to virus	traf6	IDA		Zfish	PMID:15829296
Biological Process	GO:0007165	signal transduction	Traf6	IDA		Mouse	PMID:12958312
Biological Process	GO:0050852	T cell receptor signaling pathway	TRAF6	IMP		Human	PMID:15125833
Biological Process	GO:0050852	T cell receptor signaling pathway	TRAF6	IDA		Human	PMID:23514740
Biological Process	GO:0042088	T-helper 1 type immune response	Traf6	IMP	MGI:MGI:2678775	Mouse	PMID:14499111

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern