Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRAF7
  • Mouse genes Traf7
  • Rat genes Traf7
  • Zfish genes traf7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Traf7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRAF7	IPI	UniProtKB:Q99759	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TRAF7	IPI	UniProtKB:Q99759	Human	PMID:15001576
Molecular Function	GO:0005515	protein binding	TRAF7	IPI	UniProtKB:Q9ERK0	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TRAF7	IPI	UniProtKB:Q99759	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Traf7	IPI	PR:P06876	Mouse	PMID:16162816
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRAF7	IDA		Human	PMID:14743216
Cellular Component	GO:0005829	cytosol	Traf7	IDA		Mouse	PMID:16162816
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TRAF7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Traf7	IDA		Mouse	PMID:16162816
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Traf7	IDA		Mouse	PMID:16162816
Cellular Component	GO:0005886	plasma membrane	TRAF7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000151	ubiquitin ligase complex	TRAF7	IDA		Human	PMID:14743216
Biological Process	GO:0006915	apoptotic process	TRAF7	IDA		Human	PMID:15001576
Biological Process	GO:0071354	cellular response to interleukin-6	Traf7	IDA		Mouse	PMID:16162816
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Traf7	IDA		Mouse	PMID:16162816
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	TRAF7	IMP		Human	PMID:15001576
Biological Process	GO:0043410	positive regulation of MAPK cascade	TRAF7	IDA		Human	PMID:15001576
Biological Process	GO:0043410	positive regulation of MAPK cascade	TRAF7	IDA		Human	PMID:14743216
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Traf7	IMP		Rat	PMID:30100091|RGD:151356968
Biological Process	GO:0033235	positive regulation of protein sumoylation	Traf7	IDA		Mouse	PMID:16162816
Biological Process	GO:0016567	protein ubiquitination	TRAF7	IDA		Human	PMID:14743216
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	TRAF7	IMP		Human	PMID:29961569
Biological Process	GO:0032880	regulation of protein localization	Traf7	IDA		Mouse	PMID:16162816

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern