Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TREX2
  • Mouse genes Trex2
  • Rat genes Trex2
  • Zfish genes plex9.1,plex9.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trex2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008296	3'-5'-DNA exonuclease activity	TREX2	IDA		Human	PMID:11279105
Molecular Function	GO:0003677	DNA binding	TREX2	EXP		Human	PMID:15661738
Molecular Function	GO:0000287	magnesium ion binding	TREX2	IDA		Human	PMID:11279105
Molecular Function	GO:0060090	molecular adaptor activity	TREX2	EXP		Human	PMID:15661738
Molecular Function	GO:0005515	protein binding	TREX2	IPI	UniProtKB:Q14696	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	TREX2	IPI	UniProtKB:Q91XB0	Human	PMID:11279105
Biological Process	GO:0006259	DNA metabolic process	TREX2	IDA		Human	PMID:11279105

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern