Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIB2
  • Mouse genes Trib2
  • Rat genes Trib2
  • Zfish genes trib2,trib3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trib2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRIB2	IPI	UniProtKB:Q9HBI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB2	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Trib2	IDA		Mouse	MGI:MGI:3722453|PMID:17576771
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Trib2	IDA		Mouse	MGI:MGI:4457446|PMID:20410507
Molecular Function	GO:0055106	ubiquitin-protein transferase regulator activity	Trib2	IDA		Mouse	MGI:MGI:4457446|PMID:20410507
Biological Process	GO:0007368	determination of left/right symmetry	trib3	IMP	ZFIN:ZDB-MRPHLNO-151120-1	Zfish	PMID:24292884
Biological Process	GO:0001947	heart looping	trib3	IMP	ZFIN:ZDB-MRPHLNO-151120-1	Zfish	PMID:24292884
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Trib2	IMP		Mouse	MGI:MGI:3722453|PMID:17576771
Biological Process	GO:0032693	negative regulation of interleukin-10 production	TRIB2	IMP		Human	PMID:18643775
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Trib2	IDA		Mouse	MGI:MGI:4457446|PMID:20410507

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern