Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIB3
  • Mouse genes Trib3
  • Rat genes Trib3
  • Zfish genes trib3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trib3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Trib3	IPI	UniProtKB:Q13085	Mouse	MGI:MGI:3630230|PMID:16794074
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P18848	Human	PMID:12743605
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P35638	Human	PMID:15775988
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P41182	Human	PMID:16147992
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P35638	Human	PMID:17872950
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P18848	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O14744	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P18848	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q96KN7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P18848	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q96KN7-4	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q99750	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:A0A024R8A9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:A6NJB7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O14929	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O15197-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P09067	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P09234	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P18848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P25791-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P41182	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P51687	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P51800-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P52597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P56524-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P62993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P78358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:P78412	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q0VAL7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q13111	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q13515	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q14005-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q2WGJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q3B820	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q5T8A7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q6NZ36-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q6P5X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q6W0C5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q7Z3Y9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q7Z5V6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8IVT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8IYX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8NEA6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8WUN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q92824-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q96BZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q96KN3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q96NU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q99697-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q99932-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9BRU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9BXF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9BYG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9C086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9H6L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9HC52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9NRW3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9NUL5-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9NWQ4-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9ULX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9UM07	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q9Y242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRIB3	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Trib3	IPI	UniProtKB:O00763	Mouse	MGI:MGI:3630230|PMID:16794074
Molecular Function	GO:0005515	protein binding	Trib3	IPI	UniProtKB:P31750	Mouse	MGI:MGI:3687885|PMID:12791994
Molecular Function	GO:0005515	protein binding	Trib3	IPI	UniProtKB:Q06507	Mouse	MGI:MGI:2662632|PMID:12749859
Molecular Function	GO:0019901	protein kinase binding	TRIB3	IPI	UniProtKB:P31749	Human	PMID:12791994
Molecular Function	GO:0019901	protein kinase binding	TRIB3	IPI	UniProtKB:O14733	Human	PMID:15299019
Molecular Function	GO:0019901	protein kinase binding	TRIB3	IPI	UniProtKB:Q02750	Human	PMID:15299019
Molecular Function	GO:0019901	protein kinase binding	Trib3	IPI	UniProtKB:P31750|UniProtKB:Q60823	Mouse	MGI:MGI:3687885|PMID:12791994
Molecular Function	GO:0003714	transcription corepressor activity	Trib3	IDA		Mouse	PMID:12749859
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Trib3	IPI	UniProtKB:Q9R1A8	Mouse	MGI:MGI:3630230|PMID:16794074
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Trib3	IDA		Mouse	MGI:MGI:4457446|PMID:20410507
Molecular Function	GO:0055106	ubiquitin-protein transferase regulator activity	Trib3	IDA		Mouse	MGI:MGI:4457446|PMID:20410507
Cellular Component	GO:0005654	nucleoplasm	TRIB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Trib3	IDA		Mouse	PMID:12749859
Biological Process	GO:0032869	cellular response to insulin stimulus	Trib3	IDA		Mouse	MGI:MGI:3687885|PMID:12791994
Biological Process	GO:0007368	determination of left/right symmetry	trib3	IMP	ZFIN:ZDB-MRPHLNO-151120-1	Zfish	PMID:24292884
Biological Process	GO:0006351	DNA-templated transcription	Trib3	IDA		Mouse	MGI:MGI:2662632|PMID:12749859
Biological Process	GO:0001947	heart looping	trib3	IMP	ZFIN:ZDB-MRPHLNO-151120-1	Zfish	PMID:24292884
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	TRIB3	IDA		Human	PMID:15775988
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TRIB3	IMP		Human	PMID:15775988
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trib3	IDA		Mouse	MGI:MGI:2662632|PMID:12749859
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Trib3	IMP		Mouse	MGI:MGI:3722453|PMID:17576771
Biological Process	GO:0045717	negative regulation of fatty acid biosynthetic process	Trib3	IMP		Mouse	MGI:MGI:3630230|PMID:16794074
Biological Process	GO:0006469	negative regulation of protein kinase activity	TRIB3	IDA		Human	PMID:12791994
Biological Process	GO:0006469	negative regulation of protein kinase activity	Trib3	IDA		Mouse	MGI:MGI:3687885|PMID:12791994
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TRIB3	IDA		Human	PMID:15775988
Biological Process	GO:0032092	positive regulation of protein binding	Trib3	IDA		Mouse	MGI:MGI:3630230|PMID:16794074
Biological Process	GO:0051443	positive regulation of ubiquitin-protein transferase activity	Trib3	IDA		Mouse	MGI:MGI:3630230|PMID:16794074
Biological Process	GO:0010506	regulation of autophagy	Trib3	IMP		Rat	PMID:28694771|RGD:14390049
Biological Process	GO:0010827	regulation of glucose transmembrane transport	Trib3	IDA		Mouse	MGI:MGI:3687885|PMID:12791994
Biological Process	GO:0043405	regulation of MAP kinase activity	TRIB3	IDA		Human	PMID:15299019
Biological Process	GO:0034976	response to endoplasmic reticulum stress	TRIB3	IDA		Human	PMID:15775988

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern