Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM2
  • Mouse genes Trim2
  • Rat genes Trim2
  • Zfish genes trim2a,trim2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:O88498	Human	PMID:21478148
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q6NSJ5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q9BSL1	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q96Q77	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q9BSL1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q8IZL9	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:O75382	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:O75382	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q6NSJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q96JB2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q96MP8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q96Q77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:Q9BSL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM2	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Trim2	IPI	UniProtKB:P08551	Mouse	MGI:MGI:3813391|PMID:18687884
Molecular Function	GO:0005515	protein binding	Trim2	IPI	UniProtKB:O54918	Mouse	MGI:MGI:5294518|PMID:21478148
Molecular Function	GO:0005515	protein binding	Trim2	IPI	PR:Q99104	Mouse	PMID:11432975
Molecular Function	GO:0005515	protein binding	Trim2	IPI	UniProtKB:O54918	Rat	PMID:21478148|RGD:8554586
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim2	IDA		Mouse	PMID:18687884
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim2	IDA		Mouse	PMID:21478148
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Trim2	IDA		Mouse	MGI:MGI:5294518|PMID:21478148
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Trim2	IDA		Mouse	MGI:MGI:3813391|PMID:18687884
Cellular Component	GO:0005737	cytoplasm	TRIM2	IDA		Human	PMID:11331580
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Trim2	IEP		Mouse	PMID:20439489
Biological Process	GO:0030099	myeloid cell differentiation	trim2a	IMP	ZFIN:ZDB-MRPHLNO-130410-10	Zfish	PMID:23072875
Biological Process	GO:0030099	myeloid cell differentiation	trim2a	IMP	ZFIN:ZDB-MRPHLNO-130410-9	Zfish	PMID:23072875
Biological Process	GO:0060215	primitive hemopoiesis	trim2a	IMP	ZFIN:ZDB-MRPHLNO-130410-9	Zfish	PMID:23072875
Biological Process	GO:0060215	primitive hemopoiesis	trim2a	IMP	ZFIN:ZDB-MRPHLNO-130410-10	Zfish	PMID:23072875
Biological Process	GO:0043523	regulation of neuron apoptotic process	Trim2	IMP		Mouse	MGI:MGI:3813391|PMID:18687884
Biological Process	GO:0043523	regulation of neuron apoptotic process	Trim2	IMP		Rat	PMID:21478148|RGD:8554586

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern