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Comparative GO Graph (mouse, human, rat)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Trim28

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim28
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingTRIM28IDAHumanPMID:27029610
Molecular FunctionGO:0070087chromo shadow domain bindingTRIM28IPIUniProtKB:P45973HumanPMID:15882967
Molecular FunctionGO:0003677DNA bindingTRIM28IDAHumanPMID:9016654
Molecular FunctionGO:0003677DNA bindingTrim28IDAMousePMID:22495301
Molecular FunctionGO:0003677DNA bindingTrim28IDAMousePMID:22801370
Molecular FunctionGO:0035851Krueppel-associated box domain bindingTRIM28IDAHumanPMID:17512541
Molecular FunctionGO:0035851Krueppel-associated box domain bindingTRIM28IDAHumanPMID:23665872
Molecular FunctionGO:1990841promoter-specific chromatin bindingTRIM28IDAHumanPMID:24623306
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P23198HumanPMID:10330177
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P45973HumanPMID:10330177
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P83917HumanPMID:10330177
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q13185HumanPMID:10330177
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:O75376HumanPMID:11013263
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q12873HumanPMID:16169070
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P21506HumanPMID:17512541
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q01094HumanPMID:17704056
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9Y2P7HumanPMID:18060868
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9H4L7HumanPMID:18675275
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q8C6P8HumanPMID:18854139
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P45973HumanPMID:19498464
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P62136HumanPMID:20424263
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P62140HumanPMID:20424263
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P45973HumanPMID:20562864
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q15303HumanPMID:20858735
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P43356HumanPMID:20864041
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P43357HumanPMID:20864041
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P43360HumanPMID:20864041
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9HCI5HumanPMID:20864041
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9UBF1HumanPMID:20864041
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q13185HumanPMID:20936779
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q96GC6HumanPMID:21170338
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P43357HumanPMID:21277283
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9UBF1HumanPMID:21277283
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9H4L7HumanPMID:21549307
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q12873HumanPMID:21642969
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P45973HumanPMID:21888893
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q13185HumanPMID:21888893
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q8TF47-3HumanPMID:23543754
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P21506HumanPMID:23665872
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q14587-1HumanPMID:23665872
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q96RE9HumanPMID:23665872
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9BQF6HumanPMID:24018422
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9Y2K1HumanPMID:24657165
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P45973HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P83917HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P46100HumanPMID:27029610
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9R194HumanPMID:27123980
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:P45973HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q13185HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q9BQF6HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:Q6NUN9-1HumanPMID:31856708
Molecular FunctionGO:0005515protein bindingTRIM28IPIUniProtKB:O14978HumanPMID:32051553
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:P20263|UniProtKB:P45481MouseMGI:MGI:4457953|PMID:20508149
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:O35613MouseMGI:MGI:5644194|PMID:25938714
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:Q6PR54MouseMGI:MGI:5584328|PMID:24735877
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:Q9WVE0MouseMGI:MGI:5004983|PMID:21518874
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:O54943MouseMGI:MGI:5569417|PMID:24413057
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:E9PYI1MouseMGI:MGI:5908508|PMID:27658112
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:Q99020MouseMGI:MGI:3698386|PMID:17273560
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:P97784|UniProtKB:Q9R194MouseMGI:MGI:6253084|PMID:27123980
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:Q8BHZ5MouseMGI:MGI:6202149|PMID:30017584
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:P51179MouseMGI:MGI:5644023|PMID:19321449
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:P22829|UniProtKB:Q06219MouseMGI:MGI:5644023|PMID:19321449
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:P12813MouseMGI:MGI:5644023|PMID:19321449
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:Q91YK2MousePMID:19710015
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:Q9JL10MousePMID:11331592
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:E9PYI1MousePMID:22110054
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:P83917MousePMID:8978696
Molecular FunctionGO:0005515protein bindingTrim28IPIMGI:MGI:99200MousePMID:10347202
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:Q7TPL6MousePMID:19850934
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:Q62318MousePMID:19270682
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:P83917MousePMID:10562550
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:Q8BTB4MousePMID:15469996
Molecular FunctionGO:0005515protein bindingTrim28IPIUniProtKB:Q9JIC0MousePMID:15322135
Molecular FunctionGO:0005515protein bindingTrim28IPIPR:Q9JJG5MousePMID:11331592
Molecular FunctionGO:0004672protein kinase activityTrim28IDAMousePMID:10562550
Molecular FunctionGO:0003723RNA bindingTRIM28HDAHumanPMID:22681889
Molecular FunctionGO:0019789SUMO transferase activityTRIM28EXPHumanPMID:17298944
Molecular FunctionGO:0003713transcription coactivator activityTrim28IDAMouseMGI:MGI:3698386|PMID:17273560
Molecular FunctionGO:0003713transcription coactivator activityTrim28IDAMouseMGI:MGI:5644023|PMID:19321449
Molecular FunctionGO:0003713transcription coactivator activityTrim28IDAMousePMID:11331592
Molecular FunctionGO:0003714transcription corepressor activityTRIM28IDAHumanPMID:8769649
Molecular FunctionGO:0031625ubiquitin protein ligase bindingTRIM28IDAHumanPMID:18082607
Molecular FunctionGO:0004842ubiquitin-protein transferase activityTRIM28IDAHumanPMID:18082607
Molecular FunctionGO:0008270zinc ion bindingTRIM28IDAHumanPMID:10653693
Molecular FunctionGO:0008270zinc ion bindingTRIM28IDAHumanPMID:11226167
Cellular ComponentGO:0000785chromatinTrim28IDAMousePMID:11331580
Cellular ComponentGO:0000791euchromatinTrim28IDAMousePMID:10562550
Cellular ComponentGO:0000792heterochromatinTrim28IDAMousePMID:10562550
Cellular ComponentGO:0005654nucleoplasmTRIM28IDAHumanGO_REF:0000052
Cellular ComponentGO:0005654nucleoplasmTrim28IDAMousePMID:10562550
Cellular ComponentGO:0005634nucleusTRIM28IDAHumanPMID:25593309
Cellular ComponentGO:0005634nucleusTRIM28IDAHumanPMID:8769649
Cellular ComponentGO:0005634nucleusTRIM28IDAHumanPMID:9016654
Cellular ComponentGO:0005634nucleusTrim28IDAMouseMGI:MGI:3698386|PMID:17273560
Cellular ComponentGO:0005634nucleusTrim28IDAMousePMID:15469996
Cellular ComponentGO:0005634nucleusTrim28IDAMousePMID:19270682
Cellular ComponentGO:0032991protein-containing complexTRIM28IDAHumanPMID:17512541
Cellular ComponentGO:0090575RNA polymerase II transcription regulator complexTrim28IDAMouseMGI:MGI:3698386|PMID:17273560
Biological ProcessGO:0060028convergent extension involved in axis elongationTrim28IMPMGI:MGI:1928907MousePMID:22110054
Biological ProcessGO:0043045DNA methylation involved in embryo developmentTrim28IMPMGI:MGI:1928907MousePMID:22495301
Biological ProcessGO:0006281DNA repairTRIM28IDAHumanPMID:17178852
Biological ProcessGO:0007566embryo implantationTrim28IMPMGI:MGI:1928907MousePMID:22495301
Biological ProcessGO:0060669embryonic placenta morphogenesisTrim28IMPMGI:MGI:1928907MousePMID:22110054
Biological ProcessGO:0001837epithelial to mesenchymal transitionTrim28IDAMouseMGI:MGI:3698386|PMID:17273560
Biological ProcessGO:0001701in utero embryonic developmentTrim28IMPMGI:MGI:1928907MousePMID:22495301
Biological ProcessGO:0045087innate immune responseTRIM28IDAHumanPMID:18248090
Biological ProcessGO:0045087innate immune responseTrim28IDAMousePMID:19270682
Biological ProcessGO:0045087innate immune responseTrim28IGIMGI:MGI:2143362MousePMID:19270682
Biological ProcessGO:1901536negative regulation of DNA demethylationTrim28IMPMGI:MGI:1928907MousePMID:22495301
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionTRIM28IDAHumanPMID:9016654
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionTrim28IMPMouseMGI:MGI:5004983|PMID:21518874
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionTrim28IDAMousePMID:10562550
Biological ProcessGO:0045869negative regulation of single stranded viral RNA replication via double stranded DNA intermediateTrim28IMPMouseMGI:MGI:5440670|PMID:20164836
Biological ProcessGO:0045869negative regulation of single stranded viral RNA replication via double stranded DNA intermediateTrim28IDAMousePMID:19270682
Biological ProcessGO:0045869negative regulation of single stranded viral RNA replication via double stranded DNA intermediateTrim28IGIMGI:MGI:2143362MousePMID:19270682
Biological ProcessGO:0045869negative regulation of single stranded viral RNA replication via double stranded DNA intermediateTrim28IMPMousePMID:19270682
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IITrim28IGIMGI:MGI:2142347MousePMID:22110054
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IITrim28IDAMousePMID:8986806
Biological ProcessGO:0043388positive regulation of DNA bindingTrim28IMPMousePMID:19270682
Biological ProcessGO:0043388positive regulation of DNA bindingTrim28IDAMousePMID:19270682
Biological ProcessGO:0090309positive regulation of DNA methylation-dependent heterochromatin formationTRIM28IMPHumanPMID:24623306
Biological ProcessGO:0090309positive regulation of DNA methylation-dependent heterochromatin formationTrim28IMPMouseMGI:MGI:5440670|PMID:20164836
Biological ProcessGO:0045739positive regulation of DNA repairTRIM28IDAHumanPMID:17178852
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionTrim28IDAMouseMGI:MGI:3698386|PMID:17273560
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionTrim28IDAMousePMID:11331592
Biological ProcessGO:0032092positive regulation of protein bindingTrim28IDARatPMID:12748187|RGD:1299608
Biological ProcessGO:0042307positive regulation of protein import into nucleusTRIM28IDAHumanPMID:23665872
Biological ProcessGO:0046777protein autophosphorylationTrim28IDAMousePMID:10562550
Biological ProcessGO:0006468protein phosphorylationTrim28IDAMousePMID:10562550
Biological ProcessGO:0016925protein sumoylationTRIM28IDAHumanPMID:18082607
Biological ProcessGO:2000653regulation of genetic imprintingTrim28IMPMGI:MGI:1928907MousePMID:22495301
Biological ProcessGO:0044790suppression of viral release by hostTRIM28IDAHumanPMID:18248090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory