Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Trim28

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TRIM28
- Mouse genes Trim28
- Rat genes Trim28
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim28

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	TRIM28	IDA		Human	PMID:27029610
Molecular Function	GO:0070087	chromo shadow domain binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:15882967
Molecular Function	GO:0003677	DNA binding	TRIM28	IDA		Human	PMID:9016654
Molecular Function	GO:0003677	DNA binding	Trim28	IDA		Mouse	PMID:22495301
Molecular Function	GO:0003677	DNA binding	Trim28	IDA		Mouse	PMID:22801370
Molecular Function	GO:0035851	Krueppel-associated box domain binding	TRIM28	IDA		Human	PMID:17512541
Molecular Function	GO:0035851	Krueppel-associated box domain binding	TRIM28	IDA		Human	PMID:23665872
Molecular Function	GO:1990841	promoter-specific chromatin binding	TRIM28	IDA		Human	PMID:24623306
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P23198	Human	PMID:10330177
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:10330177
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P83917	Human	PMID:10330177
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q13185	Human	PMID:10330177
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:O75376	Human	PMID:11013263
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q12873	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P21506	Human	PMID:17512541
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q01094	Human	PMID:17704056
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9Y2P7	Human	PMID:18060868
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9H4L7	Human	PMID:18675275
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q8C6P8	Human	PMID:18854139
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P62136	Human	PMID:20424263
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P62140	Human	PMID:20424263
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q15303	Human	PMID:20858735
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P43356	Human	PMID:20864041
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P43357	Human	PMID:20864041
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P43360	Human	PMID:20864041
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9HCI5	Human	PMID:20864041
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9UBF1	Human	PMID:20864041
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q13185	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q96GC6	Human	PMID:21170338
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P43357	Human	PMID:21277283
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9UBF1	Human	PMID:21277283
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9H4L7	Human	PMID:21549307
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q12873	Human	PMID:21642969
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q13185	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q8TF47-3	Human	PMID:23543754
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P21506	Human	PMID:23665872
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q14587-1	Human	PMID:23665872
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q96RE9	Human	PMID:23665872
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9BQF6	Human	PMID:24018422
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9Y2K1	Human	PMID:24657165
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P83917	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P46100	Human	PMID:27029610
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9R194	Human	PMID:27123980
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:P45973	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q13185	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q9BQF6	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:Q6NUN9-1	Human	PMID:31856708
Molecular Function	GO:0005515	protein binding	TRIM28	IPI	UniProtKB:O14978	Human	PMID:32051553
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:P20263\|UniProtKB:P45481	Mouse	MGI:MGI:4457953\|PMID:20508149
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:O35613	Mouse	MGI:MGI:5644194\|PMID:25938714
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:Q6PR54	Mouse	MGI:MGI:5584328\|PMID:24735877
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:Q9WVE0	Mouse	MGI:MGI:5004983\|PMID:21518874
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:O54943	Mouse	MGI:MGI:5569417\|PMID:24413057
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:E9PYI1	Mouse	MGI:MGI:5908508\|PMID:27658112
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:Q99020	Mouse	MGI:MGI:3698386\|PMID:17273560
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:P97784\|UniProtKB:Q9R194	Mouse	MGI:MGI:6253084\|PMID:27123980
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:Q8BHZ5	Mouse	MGI:MGI:6202149\|PMID:30017584
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:P51179	Mouse	MGI:MGI:5644023\|PMID:19321449
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:P22829\|UniProtKB:Q06219	Mouse	MGI:MGI:5644023\|PMID:19321449
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:P12813	Mouse	MGI:MGI:5644023\|PMID:19321449
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:Q91YK2	Mouse	PMID:19710015
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:Q9JL10	Mouse	PMID:11331592
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:E9PYI1	Mouse	PMID:22110054
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:P83917	Mouse	PMID:8978696
Molecular Function	GO:0005515	protein binding	Trim28	IPI	MGI:MGI:99200	Mouse	PMID:10347202
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:Q7TPL6	Mouse	PMID:19850934
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:Q62318	Mouse	PMID:19270682
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:P83917	Mouse	PMID:10562550
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:Q8BTB4	Mouse	PMID:15469996
Molecular Function	GO:0005515	protein binding	Trim28	IPI	UniProtKB:Q9JIC0	Mouse	PMID:15322135
Molecular Function	GO:0005515	protein binding	Trim28	IPI	PR:Q9JJG5	Mouse	PMID:11331592
Molecular Function	GO:0004672	protein kinase activity	Trim28	IDA		Mouse	PMID:10562550
Molecular Function	GO:0003723	RNA binding	TRIM28	HDA		Human	PMID:22681889
Molecular Function	GO:0019789	SUMO transferase activity	TRIM28	EXP		Human	PMID:17298944
Molecular Function	GO:0003713	transcription coactivator activity	Trim28	IDA		Mouse	MGI:MGI:3698386\|PMID:17273560
Molecular Function	GO:0003713	transcription coactivator activity	Trim28	IDA		Mouse	MGI:MGI:5644023\|PMID:19321449
Molecular Function	GO:0003713	transcription coactivator activity	Trim28	IDA		Mouse	PMID:11331592
Molecular Function	GO:0003714	transcription corepressor activity	TRIM28	IDA		Human	PMID:8769649
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TRIM28	IDA		Human	PMID:18082607
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRIM28	IDA		Human	PMID:18082607
Molecular Function	GO:0008270	zinc ion binding	TRIM28	IDA		Human	PMID:10653693
Molecular Function	GO:0008270	zinc ion binding	TRIM28	IDA		Human	PMID:11226167
Cellular Component	GO:0000785	chromatin	Trim28	IDA		Mouse	PMID:11331580
Cellular Component	GO:0000791	euchromatin	Trim28	IDA		Mouse	PMID:10562550
Cellular Component	GO:0000792	heterochromatin	Trim28	IDA		Mouse	PMID:10562550
Cellular Component	GO:0005654	nucleoplasm	TRIM28	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	Trim28	IDA		Mouse	PMID:10562550
Cellular Component	GO:0005634	nucleus	TRIM28	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	TRIM28	IDA		Human	PMID:8769649
Cellular Component	GO:0005634	nucleus	TRIM28	IDA		Human	PMID:9016654
Cellular Component	GO:0005634	nucleus	Trim28	IDA		Mouse	MGI:MGI:3698386\|PMID:17273560
Cellular Component	GO:0005634	nucleus	Trim28	IDA		Mouse	PMID:15469996
Cellular Component	GO:0005634	nucleus	Trim28	IDA		Mouse	PMID:19270682
Cellular Component	GO:0032991	protein-containing complex	TRIM28	IDA		Human	PMID:17512541
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Trim28	IDA		Mouse	MGI:MGI:3698386\|PMID:17273560
Biological Process	GO:0060028	convergent extension involved in axis elongation	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22110054
Biological Process	GO:0043045	DNA methylation involved in embryo development	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22495301
Biological Process	GO:0006281	DNA repair	TRIM28	IDA		Human	PMID:17178852
Biological Process	GO:0007566	embryo implantation	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22495301
Biological Process	GO:0060669	embryonic placenta morphogenesis	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22110054
Biological Process	GO:0001837	epithelial to mesenchymal transition	Trim28	IDA		Mouse	MGI:MGI:3698386\|PMID:17273560
Biological Process	GO:0001701	in utero embryonic development	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22495301
Biological Process	GO:0045087	innate immune response	TRIM28	IDA		Human	PMID:18248090
Biological Process	GO:0045087	innate immune response	Trim28	IDA		Mouse	PMID:19270682
Biological Process	GO:0045087	innate immune response	Trim28	IGI	MGI:MGI:2143362	Mouse	PMID:19270682
Biological Process	GO:1901536	negative regulation of DNA demethylation	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22495301
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TRIM28	IDA		Human	PMID:9016654
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trim28	IMP		Mouse	MGI:MGI:5004983\|PMID:21518874
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trim28	IDA		Mouse	PMID:10562550
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Trim28	IMP		Mouse	MGI:MGI:5440670\|PMID:20164836
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Trim28	IDA		Mouse	PMID:19270682
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Trim28	IGI	MGI:MGI:2143362	Mouse	PMID:19270682
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Trim28	IMP		Mouse	PMID:19270682
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Trim28	IGI	MGI:MGI:2142347	Mouse	PMID:22110054
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Trim28	IDA		Mouse	PMID:8986806
Biological Process	GO:0043388	positive regulation of DNA binding	Trim28	IMP		Mouse	PMID:19270682
Biological Process	GO:0043388	positive regulation of DNA binding	Trim28	IDA		Mouse	PMID:19270682
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	TRIM28	IMP		Human	PMID:24623306
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	Trim28	IMP		Mouse	MGI:MGI:5440670\|PMID:20164836
Biological Process	GO:0045739	positive regulation of DNA repair	TRIM28	IDA		Human	PMID:17178852
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Trim28	IDA		Mouse	MGI:MGI:3698386\|PMID:17273560
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Trim28	IDA		Mouse	PMID:11331592
Biological Process	GO:0032092	positive regulation of protein binding	Trim28	IDA		Rat	PMID:12748187\|RGD:1299608
Biological Process	GO:0042307	positive regulation of protein import into nucleus	TRIM28	IDA		Human	PMID:23665872
Biological Process	GO:0046777	protein autophosphorylation	Trim28	IDA		Mouse	PMID:10562550
Biological Process	GO:0006468	protein phosphorylation	Trim28	IDA		Mouse	PMID:10562550
Biological Process	GO:0016925	protein sumoylation	TRIM28	IDA		Human	PMID:18082607
Biological Process	GO:2000653	regulation of genetic imprinting	Trim28	IMP	MGI:MGI:1928907	Mouse	PMID:22495301
Biological Process	GO:0044790	suppression of viral release by host	TRIM28	IDA		Human	PMID:18248090

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.